{"id":15074,"date":"2020-10-16T11:19:05","date_gmt":"2020-10-16T09:19:05","guid":{"rendered":"https:\/\/idibell.cat\/?p=15074"},"modified":"2020-10-16T11:19:05","modified_gmt":"2020-10-16T09:19:05","slug":"la-concentracio-de-polifenols-en-sang-no-esta-clarament-relacionada-amb-el-risc-de-patir-de-cancer-de-tiroides","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2020\/10\/la-concentracio-de-polifenols-en-sang-no-esta-clarament-relacionada-amb-el-risc-de-patir-de-cancer-de-tiroides\/","title":{"rendered":"La concentraci\u00f3 de polifenols en sang no est\u00e0 clarament relacionada amb el risc de patir de c\u00e0ncer de tiroides"},"content":{"rendered":"<p>El <strong>c\u00e0ncer de tiroides \u00e9s un dels c\u00e0ncers endocrins m\u00e9s comuns<\/strong>, en els \u00faltims temps la seva incid\u00e8ncia ha anat augmentat paulatinament i \u00e9s fins a tres vegades m\u00e9s freq\u00fcent en dones que en homes. Es coneixen pocs factors de risc relacionats amb aquest tipus de c\u00e0ncer, \u00a0el m\u00e9s destacats s\u00f3n l\u2019exc\u00e9s de pes, l\u2019exposici\u00f3 a radiaci\u00f3 o les malalties benignes de la gl\u00e0ndula tiroides. No obstant, el paper de la dieta en la carcinog\u00e8nesi de tiroides \u00e9s encara bastant desconegut.<\/p>\n<p>Els <strong>polifenols s\u00f3n compostos presents als aliments d\u2019origen vegetal que han demostrat tenir efecte anticarcinog\u00e8nic<\/strong> en models cel\u00b7lulars i animals. Entre les seves propietats biol\u00f2giques hi destaquen els efectes antioxidants o antiinflamatoris. A m\u00e9s, s\u2019ha demostrat que indueixen la mort cel\u00b7lular i aturen la proliferaci\u00f3 de les c\u00e8l\u00b7lules del c\u00e0ncer de tiroides. Tot i els esperan\u00e7adors resultats d\u2019aquests estudis <em>in vitro<\/em> i<em> in vivo<\/em>, falten estudis cl\u00ednics en humans i epidemiol\u00f2gics que demostrin l\u2019associaci\u00f3 d\u2019aquests polifenols amb un menor risc de desenvolupar c\u00e0ncer de tiroides. Les poques aproximacions que relacionen polifenols i c\u00e0ncer de tiroides estan fetes mesurant l\u2019exposici\u00f3 a trav\u00e9s d\u2019enquestes diet\u00e8tiques, amb les limitacions d\u2019exactitud que aix\u00f2 comporta.<\/p>\n<p>Un estudi liderat pel <a href=\"https:\/\/idibell.cat\/recerca\/area-de-cancer\/programa-depidemiologia-salut-publica-prevencio-del-cancer-i-cures-palliatives\/nutricio-i-cancer\/\">Grup de Nutrici\u00f3 i C\u00e0ncer<\/a> de l\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (<a href=\"https:\/\/idibell.cat\/\">IDIBELL<\/a>) i l\u2019Institut Catal\u00e0 d\u2019Oncologia (<a href=\"http:\/\/ico.gencat.cat\/ca\/inici\">ICO<\/a>), ha avaluat la relaci\u00f3 entre la concentraci\u00f3 en sang de polifenols i el risc de desenvolupar c\u00e0ncer de tiroides. \u201c<em>L\u2019objectiu de l\u2019estudi era determinar si els polifenols podien tenir un rol preventiu en el c\u00e0ncer de tiroides, i si la detecci\u00f3 d\u2019aquests en sang representava una mesura m\u00e9s fiable que els q\u00fcestionaris\u201d<\/em>, afirma el Dr. Ra\u00fcl Zamora, l\u00edder del projecte.<\/p>\n<p>El treball, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33021645\/\">publicat a la revista <em>The American Journal of Clinical Nutrition<\/em><\/a>, ha analitzat el nivell de polifenols en sang en 785 dones amb i sense c\u00e0ncer de tiroides, de la cohort europea EPIC (<a href=\"https:\/\/epic.iarc.fr\/\">European Prospective Investigation into Cancer and Nutrition<\/a>). Els resultats mostren que no hi ha una associaci\u00f3 clara entre el consum de polifenols i el risc de desenvolupar aquest tipus de c\u00e0ncer. No obstant, l\u2019estudi detecta tres polifenols concrets relacionats amb el consum de caf\u00e8 i cereals integrals: l\u2019\u00e0cid cafeic, l\u2019\u00e0cid 3,4-dihidroxifenilpropionic, i l\u2019\u00e0cid ferulic, que semblen estar relacionats amb una menor incid\u00e8ncia de c\u00e0ncer de tiroides, concretament el subtipus papil\u00b7lar. \u201c<em>Tot i que els resultats d\u2019aquest estudi no s\u00f3n concloents, es posa el focus en aquests compostos per aprofundir en la seva investigaci\u00f3 en estudis futurs\u201d<\/em>, assegura el Dr. Zamora.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tot i que en estudis previs in vitro els polifenols han mostrat activitat anticarcinog\u00e8nica, l\u2019estudi epidemiol\u00f2gic liderat per l\u2019IDIBELL i l\u2019ICO no ha trobat associaci\u00f3 entre la seva concentraci\u00f3 en sang i el c\u00e0ncer de tiroides.<\/p>\n","protected":false},"author":8,"featured_media":15076,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[332,369,454],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 14:51:42","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/15074"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=15074"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/15074\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/15076"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=15074"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=15074"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=15074"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}