{"id":14071,"date":"2020-08-18T12:40:44","date_gmt":"2020-08-18T10:40:44","guid":{"rendered":"https:\/\/idibell.cat\/?p=14071"},"modified":"2020-09-01T10:43:38","modified_gmt":"2020-09-01T08:43:38","slug":"edat-i-sexe-masculi-factors-clau-en-el-risc-de-mortalitat-dingres-hospitalari-per-la-covid-19","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2020\/08\/edat-i-sexe-masculi-factors-clau-en-el-risc-de-mortalitat-dingres-hospitalari-per-la-covid-19\/","title":{"rendered":"Edat i sexe mascul\u00ed, factors clau en el risc de mortalitat d&#8217;ingr\u00e9s hospitalari per la COVID-19"},"content":{"rendered":"<h6><strong>Un estudi dut a terme en 127 centres hospitalaris espanyols i amb la participaci\u00f3 de l\u2019IDIBELL suma una informaci\u00f3 completa sobre les complicacions i pron\u00f2stic dels primers 4.035 pacients amb COVID-19 ingressats al pa\u00eds.<\/strong><\/h6>\n<p>&nbsp;<\/p>\n<h6><\/h6>\n<h6><strong>La investigaci\u00f3 tamb\u00e9 ha perm\u00e8s identificar algunes variables que s&#8217;associen amb pitjor pron\u00f2stic, el que ser\u00e0 de gran utilitat per a la identificaci\u00f3 d&#8217;aquells pacients amb major risc de mort durant l&#8217;ingr\u00e9s.<\/strong><\/h6>\n<p>&nbsp;<\/p>\n<p>M\u00e9s de 500 professionals sanitaris de 127 centres hospitalaris, incl\u00f2s el Dr Jordi Carratal\u00e0, metge i investigador a l&#8217;Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) i l&#8217;Hospital Universitari de Bellvitge, han col\u00b7laborat en l&#8217;estudi COVID-19@Spain, promogut per la Societat Espanyola de Malalties Infeccioses i Microbiologia Cl\u00ednica (SEIMC) per determinar les caracter\u00edstiques epidemiol\u00f2giques i cl\u00edniques dels pacients hospitalitzats amb COVID-19 en tot el territori espanyol, i identificar els factors predictors de mort.<\/p>\n<p>La foto fixa i troballes d&#8217;aquesta cohort nacional, que va analitzar els primers 4.035 pacients amb COVID-19 ingressats des de l&#8217;inici de l&#8217;epid\u00e8mia fins el 17 de mar\u00e7 de 2020, mostra que l&#8217;edat mitjana va ser de 70 anys, el 25% tenia m\u00e9s de 80 anys, i el 61% eren homes. M\u00e9s del 70% tenia alguna malaltia subjacent i m\u00e9s del 25% patia com a m\u00ednim tres malalties de base. Les m\u00e9s freq\u00fcents van ser hipertensi\u00f3 arterial, cardiopatia cr\u00f2nica, diabetis, MPOC i obesitat.<\/p>\n<p>Els s\u00edmptomes m\u00e9s comuns van ser febre, tos, malestar general i dificultat per respirar. Durant l&#8217;hospitalitzaci\u00f3, un de cada tres pacients va desenvolupar s\u00edndrome del destret respiratori agut, el 18,5% van ingressar a la UCI i el 15,5% van ser sotmesos a ventilaci\u00f3 mec\u00e0nica. Van morir el 28% dels pacients i la mort va oc\u00f3rrer com a mitjana 10 dies despr\u00e9s de l&#8217;ingr\u00e9s. La mortalitat va ser de el 59,3% en els pacients amb destret respiratori, de l&#8217;54.9% en aquells amb edat igual o superior a 80 anys, de el 47,7% en aquells que tenien tres o m\u00e9s malalties subjacents, de l&#8217;45,7% aquells sotmesos a ventilaci\u00f3 mec\u00e0nica i de l&#8217;42,4% aquells ingressats a UCI.<\/p>\n<p>L&#8217;an\u00e0lisi estad\u00edstica va posar de manifest l&#8217;exist\u00e8ncia de 17 variables que es van associar amb major risc de mort, el m\u00e9s determinant dels quals va ser l&#8217;edat. Tamb\u00e9 es van associar amb major risc de mort el sexe mascul\u00ed, la pres\u00e8ncia d&#8217;algunes malalties subjacents (hipertensi\u00f3 arterial, obesitat, cirrosi hep\u00e0tica, malaltia neurol\u00f2gica cr\u00f2nica, c\u00e0ncer actiu i dem\u00e8ncia), algunes caracter\u00edstiques cl\u00edniques com dificultat respirat\u00f2ria o disminuci\u00f3 de la consci\u00e8ncia, la baixa oxigenaci\u00f3 de la sang i algunes proves de laboratori com el quocient neutr\u00f2fils\/limf\u00f2cits i la funci\u00f3 renal.<\/p>\n<p>Val la pena ressaltar que no hi va haver difer\u00e8ncies en la mortalitat ajustada per gravetat entre les diferents zones geogr\u00e0fiques, el que parla a favor de l&#8217;homogene\u00eftat en la qualitat assistencial al pa\u00eds.<\/p>\n<p>Fins a la data, s&#8217;han publicat tres cohorts nacionals de pacients hospitalitzats amb COVID-19, dues de la Xina i una de Regne Unit. En totes elles es va fer una descripci\u00f3 m\u00e9s o menys detallada dels pacients, la malaltia i l&#8217;evoluci\u00f3; per\u00f2, en cap de les tres es va examinar el paper de les proves de laboratori en el pron\u00f2stic de la malaltia.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Comit\u00e8 Cient\u00edfic<\/strong><\/p>\n<p>COVID-19@Spain compta amb un Comit\u00e8 Cient\u00edfic integrat per investigadors cl\u00ednics de diversos hospitals espanyols com l&#8217;Hospital Gregorio Mara\u00f1\u00f3n, l&#8217;Hospital La Paz i l&#8217;Hospital Infanta Leonor de Madrid; els Hospitals Verge Macarena i Verge del Roc\u00edo de Sevilla i l&#8217;IDIBELL\/Hospital de Bellvitge a Barcelona. El comit\u00e8 compta a m\u00e9s amb investigadors de el Centre Nacional d&#8217;Epidemiologia de l&#8217;Institut de Salut Carlos III i de la Fundaci\u00f3 SEIMC-GESIDA.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Un estudi amb la participaci\u00f3 de l\u2019IDIBELL suma una informaci\u00f3 completa sobre les complicacions i pron\u00f2stic dels primers 4.035 pacients amb COVID-19 ingressats al pa\u00eds.<\/p>\n","protected":false},"author":8,"featured_media":14072,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[391],"tags":[],"class_list":["post-14071","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-infeccions-respiratories-i-en-lhoste-immunocompromes"],"publishpress_future_action":{"enabled":false,"date":"2024-12-01 13:07:27","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/14071","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=14071"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/14071\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/14072"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=14071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=14071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=14071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}