Tres projectes d’investigaci\u00f3 de l’IDIBELL rebran finan\u00e7ament per part del fons Covid-19 impulsat des de l’Instituto de Salud Carlos III (ISCIII). Aquest fons va destinat a projectes de recerca que millorin a curt termini el coneixement del virus i la gesti\u00f3 de la malaltia, fins al moment s’han concedit fins a 126 projectes, dels 1500 presentats, que engloben el 90% del total de pressupost.<\/p>\n
Es tracta de projectes ja en marxa i de noves iniciatives centrades en \u00e0mbits diversos de la recerca de la Covid-19. Els tres projectes seleccionats de l’IDIBELL se centren en l’estudi de la biologia del virus, les manifestacions cl\u00edniques i les relacions amb altres malalties, i l’estudi de la seva immunitat. Aquests projectes han estat avaluats i seleccionats per un comit\u00e8 cientifico-t\u00e8cnic creat per a coordinar la concessi\u00f3 d’aquestes ajudes en concret.<\/p>\n
<\/p>\n
An\u00e0lisis del perfil transcript\u00f2mic de pacients amb Covid-19 (TRANSCOVID)<\/u><\/p>\n
El projecte TRANSCOVID analitzar\u00e0 els gens que expressen els pacients ingressats per Covid-19. L’equip del Dr. Jordi Carratal\u00e0, coordinador del programa de malalties infeccioses i trasplantaments de l’IDIBELL, pret\u00e9n definir i caracteritzar el perfil transcript\u00f2mic d’aquells pacients que desenvolupen la s\u00edndrome de la dificultat respirat\u00f2ria aguda, i aix\u00ed poder determinar els gens implicats en el desenvolupament m\u00e9s greu de la malaltia.<\/p>\n
<\/p>\n
Caracteritzaci\u00f3 del SARS-CoV-2 (COV-Immunity)<\/u><\/p>\n
El projecte del Dr. Oriol Bestard, investigador principal del grup de nefrologia i trasplantament renal de l’IDIBELL, t\u00e9 per objectiu caracteritzar la resposta immunit\u00e0ria de mem\u00f2ria cel\u00b7lular protectora que genera el virus en individus immunocompetents i en pacients immunodeprimits, com els pacients trasplantats o aquells amb processos neopl\u00e0sics actius. L’estudi se centrar\u00e0 a entendre la longevitat i capacitat protectora de la resposta immunit\u00e0ria adaptativa que es genera enfront al virus, alhora es definir\u00e0 la capacitat de variaci\u00f3 gen\u00e8tica i antig\u00e8nica del SARS-CoV-2.<\/p>\n
<\/p>\n
Definici\u00f3 del perfil immunitari de risc en la Covid-19<\/u><\/p>\n
El Dr. Jordi Bas, cap del departament d’immunologia de l’Hospital Universitari de Bellvitge, col\u00b7labora en un projecte coordinat, impulsat pel servei d’immunologia de l\u2019Hospital Vall d\u2019Hebron i participat tamb\u00e9 pel servei d\u2019Immunologia de l\u2019Hospital Germans Trias i Pujol. L’objectiu \u00e9s classificar l’estat de la resposta immunit\u00e0ria innata i adaptativa, i generar un algoritme pron\u00f2stic i d’orientaci\u00f3 terap\u00e8utica a partir de l\u2019estudi de l\u2019evoluci\u00f3 de les poblacions limfocit\u00e0ries, producci\u00f3 de citocines i identificaci\u00f3 de les vies moleculars de resposta immunit\u00e0ria activades<\/p>\n","protected":false},"excerpt":{"rendered":"
Els projectes se centren en l\u2019estudi de la biologia del virus, la immunitat que genera i les manifestacions cl\u00edniques de la malaltia.<\/p>\n","protected":false},"author":8,"featured_media":12911,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[339,479],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 20:53:44","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/12910"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=12910"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/12910\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/12911"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=12910"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=12910"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=12910"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}