{"id":12713,"date":"2020-05-07T12:00:20","date_gmt":"2020-05-07T10:00:20","guid":{"rendered":"https:\/\/idibell.cat\/?p=12713"},"modified":"2020-05-16T20:03:42","modified_gmt":"2020-05-16T18:03:42","slug":"estudien-la-concordanca-molecular-entre-els-tumors-primaris-de-cancer-colorectal-i-les-seves-respectives-metastasis-al-fetge","status":"publish","type":"post","link":"https:\/\/idibell.cat\/2020\/05\/estudien-la-concordanca-molecular-entre-els-tumors-primaris-de-cancer-colorectal-i-les-seves-respectives-metastasis-al-fetge\/","title":{"rendered":"Estudien la concordan\u00e7a molecular entre els tumors primaris de c\u00e0ncer colorectal i les seves respectives met\u00e0stasis al fetge"},"content":{"rendered":"

El c\u00e0ncer colorectal<\/strong> \u00e9s un dels c\u00e0ncers m\u00e9s comuns en tot el m\u00f3n, afecta fins a 1\u20192 bilions de persones l\u2019any, causant al voltant de 600.000 morts. La seva progressi\u00f3 acostuma a ser asimptom\u00e0tica, el que sovint comporta que el diagn\u00f2stic es faci quan ja s\u2019ha desenvolupat met\u00e0stasi<\/strong>. L\u2019elecci\u00f3 del tractament per combatre aquest tipus de c\u00e0ncer t\u00e9 en conte les caracter\u00edstiques del tumor, no obstant l\u2019obtenci\u00f3 de bi\u00f2psies del teixit metast\u00e0tic acostuma a ser complicada, i l\u2019elecci\u00f3 de tractament s\u2019acaba fent en base al an\u00e0lisi del tumor primari. Aix\u00ed doncs, con\u00e8ixer les caracter\u00edstiques del tumor primari \u00e9s suficient per determinar el tractament?<\/p>\n

Els equips del Dr. Ramon Salazar i del Dr. Alberto Villanueva, de l\u2019Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) i de l\u2019Institut Catal\u00e0 d\u2019Oncologia (ICO), han participat en un estudi, publicat a la revista International Journal of Cancer<\/em><\/a>, que ha analitzat i comparat els patrons d\u2019expressi\u00f3 g\u00e8nica de tumors primaris i les seves respectives met\u00e0stasi al fetge. Aquest tipus de classificaci\u00f3 divideix els tumors en subtipus moleculars<\/strong> en funci\u00f3 de l\u2019activaci\u00f3 de diferents processos biol\u00f2gics. S\u2019han analitzat fins a 82 parelles de tumors, i els resultats validen l\u2019an\u00e0lisi molecular dels tumors primaris com a indicador per l\u2019elecci\u00f3 de tractament. En conclusi\u00f3, aquest estudi posa de rellev\u00e0ncia que l\u2019origen del teixit pot tenir majors conseq\u00fc\u00e8ncies per a la medicina de precisi\u00f3 del c\u00e0ncer colorectal.<\/p>\n","protected":false},"excerpt":{"rendered":"

Investigadors del IDIBELL i del ICO participen en la classificaci\u00f3 en subtipus moleculars de parelles de c\u00e0ncer colorectals i met\u00e0stasi de fetge per definir-ne la seva correlaci\u00f3.<\/p>\n","protected":false},"author":8,"featured_media":12714,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[332,375,447,346],"tags":[],"class_list":["post-12713","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","category-colorectal","category-p-de-mecanismes-molelculars-i-terapia-experimental-en-oncologia-oncobell","category-quimioresistencia-tumoral-i-estromal"],"publishpress_future_action":{"enabled":false,"date":"2025-03-02 11:19:44","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/12713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=12713"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/posts\/12713\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/12714"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=12713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/categories?post=12713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=12713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}