{"id":3036,"date":"2019-10-10T04:53:16","date_gmt":"2019-10-10T02:53:16","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=3036"},"modified":"2024-11-21T11:23:12","modified_gmt":"2024-11-21T10:23:12","slug":"infeccions-de-dificil-tractament-i-us-dantimicrobians","status":"publish","type":"page","link":"https:\/\/idibell.cat\/recerca\/area-de-medicina-translacional\/programa-de-malalties-infeccioses-i-transplantaments\/infeccions-de-dificil-tractament-i-us-dantimicrobians\/","title":{"rendered":"Infeccions de dif\u00edcil tractament i \u00fas d\u2019antimicrobians"},"content":{"rendered":"\n<h1>\n\t\tInfeccions de dif\u00edcil tractament i \u00fas d&#8217;antimicrobians\n\t<\/h1>\n<h3>\n\t\tResum\n\t<\/h3>\n\t<p>El grup de recerca en infeccions de dif\u00edcil tractament i \u00fas d&#8217;antimicrobians engloba una s\u00e8rie de l\u00ednies de recerca cl\u00ednica i experimental diverses, per\u00f2 que tenen en com\u00fa la dificultat en aconseguir una efic\u00e0cia i una utilitzaci\u00f3 en medicaments antimicrobians \u00f2ptima. En tots els casos, l&#8217;objectiu d&#8217;estudi \u00e9s l&#8217;optimitzaci\u00f3 dels medicaments antimicrobians, els seus mecanismes d&#8217;acci\u00f3 i la seva capacitat d&#8217;arribar als organismes pat\u00f2gens.<\/p>\n<h2>632<\/h2>\n<h2>Publicacions<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/04\/lo.jpg\" alt=\"lo\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"lo\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">L\u00ednies estrat\u00e8giques<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\tInfeccions del SNC<br \/>\nInfeccions per P.aeruginosa multiresistent (MR)<br \/>\nOsteoartritis i infeccions associades a implants osteoarticulars<br \/>\n\u00das d&#8217;antimicrobians\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Publicacions seleccionades<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>P\u00e9rez Galera,S;Bravo Ferrer,JM;Paniagua,M;Kostyanev,T;de Kraker,M;Feifel,J;Sojo Dorado,J et al, <strong>Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)<\/strong>., EClinicalMedicine, 2023;57101871-101871, doi:10.1016\/j.eclinm.2023.101871<\/li>\n<li>Saiz Escobedo,L;Cadenas Jim\u00e9nez,I;Olmos,R;Carrera Salinas,A;Berbel,D;C\u00e0mara,J;Tubau,F et al, <strong>Detection of blaCTX-M-15 in an integrative and conjugative element in four extensively drug-resistant<i> Haemophilus<\/i><i> parainfluenzae<\/i> strains causing urethritis<\/strong>, Int. J. Antimicrob. Agents, 2023;62(5):106991-106991, doi:10.1016\/j.ijantimicag.2023.106991<\/li>\n<li>Benavent,E;Ulldemolins,M;El Haj,C;Rigo Bonnin,R;Yu,HD;Wang,LY;Wickremasinghe,H et al, <strong>Efficacy of meropenem extended infusion vs intermittent bolus monotherapy and in combination with colistin against Pseudomonas aeruginosa biofilm<\/strong>, Int. J. Antimicrob. Agents, 2023;62(2):106856-106856, doi:10.1016\/j.ijantimicag.2023.106856<\/li>\n<li>Lloberas,N;Griny\u00f3,JM;Colom,H;Vidal Alabr\u00f3,A;Fontova,P;Rigo Bonnin,R;Padr\u00f3,A et al, A prospective controlled, randomized clinical trial of kidney transplant recipients developed personalized tacrolimus dosing using model-based Bayesian Prediction, Kidney Int., 2023;104(4):840-850, doi:10.1016\/j.kint.2023.06.021<\/li>\n<li>Benavent,E;Kortajarena,X;Sobrino Diaz,B;Gasch,O;Rodr\u00edguez Pardo,D;Escudero Sanchez,R; Bahamonde,A et al, <strong>Vertebral osteomyelitis after spine instrumentation surgery: risk factors and management<\/strong>, J. Hosp. Infect., 2023;140102-109, doi:10.1016\/j.jhin.2023.07.008<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Projectes seleccionats<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>FIS23016. <strong>Problem\u00e1tica de la infecci\u00f3n asociada a biofilms de P. aeruginosa XDR\/DTR: evaluaci\u00f3n de alternativas terap\u00e9uticas y de su impacto en la estructura del biofilm y el resistoma<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 141.250\u20ac. 2024-2026. PI: Murillo Rubio, Oscar.<\/li>\n<li>19FIS018. <strong>Vasculitis cerebral post meningitis neumoc\u00f3cica: Factores relacionados y etiopatogenia<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 111.320\u20ac. 2019-2023. PI: Cabellos M\u00ednguez, Mar\u00eda del Carmen.<\/li>\n<li>19MEC020. <strong>AYUDAS PARA LA FORMACION DE DOCTORES DEL PROGRAMA NACIONAL DE FORMACION DE PROFESORADO UNIVERSITARIO (FPU). MINISTERIO DE EDUCACI\u00d3N Y FORMACI\u00d3N PROFESIONAL<\/strong>. Budget: 81.493,77\u20ac. 2019-2023. PI: Murillo Rubio, Oscar.<\/li>\n<li>20FIS009. <strong>Optimizing the treatment with beta-lactams against biofilm-related infections caused by Gramnegative bacilli: the need for redefining their pharmacodynamics<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 49.610\u20ac. 2020-2023. PI: Murillo Rubio, Oscar.<\/li>\n<li>20FIS006. <strong>Impacto de un programa de antibi\u00f3ticos con acceso a expertos en enfermedades infecciosas en atenci\u00f3n primaria: Estudio controlado no ciego con aleatorizaci\u00f3n por conglomerados (PROAP)<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 24.200\u20ac. 2020-2023. PI: Shaw Perujo, Evelyn.<\/li>\n<\/ul>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2019\/10\/murillo-rubio-oscar-150x150.jpg\" alt=\"Murillo Rubio, Oscar\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"murillo-rubio-oscar\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMurillo Rubio, Oscar\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:omurillo@idibell.cat\" title=\"omurillo@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tomurillo@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tInvestigadors principals\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2019\/10\/murillo-rubio-oscar-150x150.jpg\" alt=\"Murillo Rubio, Oscar\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"murillo-rubio-oscar\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMurillo Rubio, Oscar\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:omurillo@idibell.cat\" title=\"omurillo@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tomurillo@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2022\/05\/Arkaitz-Imaz-Vacas-150x150.jpg\" alt=\"Arkaitz-Imaz-Vacas\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Arkaitz-Imaz-Vacas\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tImaz Vacas, Arkaitz\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:aimaz@idibell.cat\" title=\"aimaz@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\taimaz@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2019\/10\/ariza-cardenal-xavier-150x150.jpg\" alt=\"ariza-cardenal-xavier\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"ariza-cardenal-xavier\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tAriza Cardenal, Xavier\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailtoxariza@idibell.cat\" title=\"xariza@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\txariza@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/12\/Carmen-Cabellos-Minguez-150x150.jpg\" alt=\"Carmen-Cabellos-Minguez\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Carmen-Cabellos-Minguez\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tCabellos M\u00ednguez, M. Carmen\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:mcabellos@idibell.cat\" title=\"mcabellos@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tmcabellos@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/04\/Evelyn-Shaw-Perujo-150x150.jpg\" alt=\"Evelyn-Shaw-Perujo\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Evelyn-Shaw-Perujo\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tShaw Perujo, Evelyn\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:eshaw@idibell.cat\" title=\"eshaw@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\teshaw@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tEquip\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tCaps de grup\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tInvestigadors\/es principals\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tInvestigadors\/es cl\u00ednics\/ques\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tInvestigadors\/es postdoctorals\t\t\t\t<\/a>\n\t\t\t\t\t\tCaps de grup\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Murillo Rubio, Oscar<\/li>\n<\/ul>\n\t\t\t\t\t\tInvestigadors\/es principals\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Ariza Cardenal, Xavier<\/li>\n<li>Cabellos M\u00ednguez, M Carmen<\/li>\n<li>Shaw Perujo, Evelyn<\/li>\n<li>Imaz Vacas, Arkaitz<\/li>\n<\/ul>\n\t\t\t\t\t\tInvestigadors\/es cl\u00ednics\/ques\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Cabo Cabo, Francisco<\/li>\n<li>Rigo Bonnin, Ra\u00fal<\/li>\n<li>Soldevila Boixader, Laura<\/li>\n<li>Tubau Quintano, Mari Fe<\/li>\n<li>Benavent Palomares, Eva<\/li>\n<li>Saumoy Linares, Maria<\/li>\n<\/ul>\n\t\t\t\t\t\tInvestigadors\/es postdoctorals\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>El Haj Hidalgo, Cristina<\/li>\n<\/ul>\n<h2>\n\t\tNot\u00edcies relacionades\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/24243\" content=\"Els resultats d'una recerca liderada a Bellvitge permetr\u00e0 avan\u00e7ar en la lluita contra la bacteri\u00e8mia\" \/><meta itemprop=\"datePublished\" content=\"2023-10-03\" \/><meta itemprop=\"dateModified\" content=\"2023-10-03\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" 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d&#8217;antimicrobians Resum El grup de recerca en infeccions de dif\u00edcil tractament i \u00fas d&#8217;antimicrobians engloba una s\u00e8rie de l\u00ednies de recerca cl\u00ednica i experimental diverses, per\u00f2 que tenen en com\u00fa la dificultat en aconseguir una efic\u00e0cia i una utilitzaci\u00f3 en medicaments antimicrobians \u00f2ptima. 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