{"id":2669,"date":"2019-10-07T14:19:01","date_gmt":"2019-10-07T12:19:01","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2669"},"modified":"2024-05-16T14:29:05","modified_gmt":"2024-05-16T12:29:05","slug":"fisiologia-i-patologia-de-la-relacio-funcional-glia-neurona","status":"publish","type":"page","link":"https:\/\/idibell.cat\/recerca\/area-de-medicina-translacional\/programa-de-gens-malaltia-i-terapia\/fisiologia-i-patologia-de-la-relacio-funcional-glia-neurona\/","title":{"rendered":"Fisiologia i patologia de la relaci\u00f3 funcional glia-neurona"},"content":{"rendered":"\n
El clorur \u00e9s l’ani\u00f3 m\u00e9s abundant en organismes. Els canals de clor de membrana plasm\u00e0tics de la fam\u00edlia CLC i LRRC8 s\u00f3n importants per a diverses funcions fisiol\u00f2giques, com ara la regulaci\u00f3 de l’excitabilitat a les c\u00e8l\u00b7lules nervioses i el m\u00fascul, tant per a la regulaci\u00f3 del volum cel\u00b7lular com per al transport transepitelial. Els rols fisiol\u00f2gics de diversos canals de clor s\u00f3n il\u00b7lustrats en malalties heredit\u00e0ries humanes causades per mutacions en els gens o subunitats auxiliars que regulen les seves funcions. L’objectiu del grup \u00e9s, doncs,\u00a0 intentar comprendre la regulaci\u00f3 del canal de clor per proporcionar solucions terap\u00e8utiques als pacients afectats. Utilitzem un enfocament multidisciplinari aplicant m\u00e8todes d’imatge, electrofisiologia i bioqu\u00edmica en models de ratolins i peix zebra.<\/p>\n
– 18MAR001. Development of novel inhibitors of the chloride channel LRRC8\/VRAC, a novel player in ischemia. (201710.30). FUNDACIO IDIBELL; FUNDACI\u00d3 LA MARAT\u00d3 DE TV3; UNIVERSITAT DE BARCELONA. Importe Concedido:199.936,53\u20ac 2018-2021. IP:ESTEVEZ POVEDANO,RAUL.<\/p>\n
– Regulation of chloride channels in health and disease. UB. MICINN. 242000 \u20ac. 2019-2021<\/p>\n
– Estudios iniciales para determinar la estructura 3D de MLC1. CIBERER. 40000 \u20ac 2020-2021<\/p>\n
– Characterization of a zebrafish model of myotonia congenita. CIBERER. 40000 \u20ac 2021-2022<\/p>\n\t\t\t\t\n
Fisiologia i patologia de la relaci\u00f3 funcional glia-neurona Resum El clorur \u00e9s l’ani\u00f3 m\u00e9s abundant en organismes. Els canals de clor de membrana plasm\u00e0tics de la fam\u00edlia CLC i LRRC8 s\u00f3n importants per a diverses funcions fisiol\u00f2giques, com ara la regulaci\u00f3 de l’excitabilitat a les c\u00e8l\u00b7lules nervioses i el m\u00fascul, tant per a la regulaci\u00f3 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":552,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-2669","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2024-12-29 09:16:29","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/2669","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=2669"}],"version-history":[{"count":6,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/2669\/revisions"}],"predecessor-version":[{"id":25654,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/2669\/revisions\/25654"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/552"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=2669"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}