{"id":2364,"date":"2019-10-05T20:19:55","date_gmt":"2019-10-05T18:19:55","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2364"},"modified":"2024-06-06T15:47:51","modified_gmt":"2024-06-06T13:47:51","slug":"transformacio-i-metastasi","status":"publish","type":"page","link":"https:\/\/idibell.cat\/recerca\/area-de-cancer\/programa-de-mecanismes-moleculars-i-terapia-experimental-en-oncologia-oncobell\/transformacio-i-metastasi\/","title":{"rendered":"Transformaci\u00f3 i met\u00e0stasi"},"content":{"rendered":"\n<h1>\n\t\tTransformaci\u00f3 i met\u00e0stasi\n\t<\/h1>\n<h3>\n\t\tResum\n\t<\/h3>\n\t<p>La recerca del grup t\u00e9 com a objectiu identificar noves dianes terap\u00e8utiques per al c\u00e0ncer que es puguin traduir directament en estrat\u00e8gies efectives de prevenci\u00f3 o tractament. Es volen comprendre les vies de senyalitzaci\u00f3 implicades en la regulaci\u00f3 de c\u00e8l\u00b7lules mare epitelials i el desenvolupament del teixit sa, les seves alteracions durant el c\u00e0ncer i la met\u00e0stasi, i les interaccions entre les c\u00e8l\u00b7lules tumorals i el seu\u00a0microambient.<\/p>\n<p>L&#8217;experi\u00e8ncia dels seus membres inclou el desenvolupament de la gl\u00e0ndula mam\u00e0ria, el c\u00e0ncer de mama i la immunologia.<\/p>\n<p>El grup t\u00e9 un enfocament multidisciplinari i utilitza models de ratol\u00ed modificats gen\u00e8ticament, mostres cl\u00edniques, xenoempelts derivats del pacient, organoides i cultius 3D, i t\u00e8cniques de biologia molecular i cel\u00b7lular per traduir la investigaci\u00f3 b\u00e0sica en resultats cl\u00ednicament rellevants.<\/p>\n<p>&nbsp;<\/p>\n<h2>147<\/h2>\n<h2>Publicacions<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/04\/608_gonzalez2.jpg\" alt=\"608_gonzalez2\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"608_gonzalez2\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">L\u00ednies estrat\u00e8giques<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\tIdentificar noves estrat\u00e8gies terap\u00e8utiques i mecanismes de resist\u00e8ncia als tractaments actuals en c\u00e0ncer de mama<br \/>\nAvaluar el rol de la via de senyalitzaci\u00f3 RANK en l&#8217;home\u00f2stasi epitelial, la inflamaci\u00f3 i el c\u00e0ncer, i el seu potencial com a objectiu terap\u00e8utic.\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Publicacions seleccionades<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Rocha,AS;Collado Sol\u00e9,A;Gra\u00f1a Castro,O;Redondo Pedraza,J;Soria Alcaide,G; Cordero,A; Santamaria,PG et al, <strong>Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands<\/strong>, Nat. Commun., 2023;14(1):6213-6213, doi:10.1038\/s41467-023-41741-5<\/li>\n<li>Ciscar,M;Trinidad,EM;Perez Chacon,G;Alsaleem,M;Jimenez,M;Jimenez Santos,MJ;Perez Montoyo,H et al, <strong>RANK is a poor prognosis marker and a therapeutic target in ER-negative postmenopausal breast cancer<\/strong>., EMBO Mol. Med., 2023;15(4):doi:10.15252\/emmm.202216715<\/li>\n<li>Garcia Tejedor,A;Ortega Exposito,C;Salinas,S;Luzardo Gonzalez,A;Falo,C;Martinez Perez,E;Perez Montero,H et al, <strong>Axillary lymph node dissection versus radiotherapy in breast cancer with positive sentinel nodes after neoadjuvant therapy (ADARNAT trial)<\/strong>, Front. Oncol., 2023;131184021-1184021, doi:10.3389\/fonc.2023.1184021<\/li>\n<li>Cordero,A;Santamaria,PG;Gonzalez Suarez,E, <strong>Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential<\/strong>, J. Mammary Gland Biol. Neoplasia, 2023;28(1):2-2, doi:10.1007\/s10911-023-09530-4<\/li>\n<li>Gomes,I;Gallego Paez,LM;Jim\u00e9nez,M;Santamaria,PG;Mansinho,A;Sousa,R;Abreu,C et al, <strong>Co-targeting RANK pathway treats and prevents acquired resistance to CDK4\/6 inhibitors in luminal breast cancer<\/strong>, Cell Rep. Med., 2023;4(8):101120-101120, doi:10.1016\/j.xcrm.2023.101120<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Projectes seleccionats<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>16CEE012. <strong>PLEIO-RANK:Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity<\/strong>. COMISSI\u00d3 EUROPEA. Budget: 1.999.960,01\u20ac. 2016-2023. PI: GONZALEZ SUAREZ, EVA.<\/li>\n<li>17PRV003.<strong> An open label biomarker pilot study of the antitumoral activity of denosumab in the pre- operative setting of early breast cancer<\/strong>. Amgen Inc. Budget: 517.652\u20ac. 2019-2023. PI: Eva Gonzalez Suarez.<\/li>\n<li>2024-099-1. <strong>ESTUDIO EN FASE III, ABIERTO, ALEATORIZADO PARA EVALUAR LA EFICACIA Y LA SEGURIDAD DEL TRATAMIENTO PROLONGADO CON CAMIZESTRANT (AZD9833, UN DEGRADADOR SELECTIVO DEL RECEPTOR DE ESTR\u00d3GENOS ORAL Y DE NUEVA GENERACI\u00d3N) FRENTE AL TRATAMIENTO ENDOCRINO EST\u00c1NDAR (INHIBIDOR DE LA AROMATASA O TAMOXIFENO) EN PACIENTES CON C\u00c1NCER DE MAMA TEMPRANO ER+\/HER2- Y UN RIESGO INTERMEDIO O ALTO DE RECA\u00cdDA QUE HAN COMPLETADO TRATAMIENTO LOCORREGIONAL DEFINITIVO Y AL MENOS 2 A\u00d1OS DE TRATAMIENTO ENDOCRINO ADYUVANTE EST\u00c1NDAR SIN RECA\u00cdDA DE LA ENFERMEDAD<\/strong>. Budget: 62.320\u20ac. 2023- . PI: VETHENCOURT CASADO, ANDREA CAROLINA.<\/li>\n<li>21PSJ002. <strong>Estudio de biomarcadores de la actividad antitumoral del denosumab y su papel como modulador de la respuesta inmune en el c\u00e1ncer de mama precoz: IO-D-BIOMARK<\/strong>. Fundaci\u00f3n Grupo Espa\u00f1ol de Investigaci\u00f3n en Cancer de Mama (GEICAM). Budget: 42.000\u20ac. 2021-2024. PI: VETHENCOURT CASADO, ANDREA CAROLINA.<\/li>\n<li>2023-571-1. <strong>ROLE OF RANK IN MYELOID CELLS AND TUMOR DEVELOPMENT<\/strong>. Fundaci\u00f3 &#8220;LA CAIXA&#8221;. 2023- . PI: GONZALEZ SUAREZ, EVA.<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\">M\u00e9s informaci\u00f3<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>El grup ha rebut un finan\u00e7ament competitiu ininterromput d&#8217;organismes p\u00fablics i privats, nacionals i internacionals, amb un total de 17 beques. Entre les ag\u00e8ncies finan\u00e7adores destaquen: MINECO, ISCIII, AECC, Fundaci\u00f3 Mutua Madrile\u00f1a, Marat\u00f3 de TV3, i tamb\u00e9 les ag\u00e8ncies internacionals m\u00e9s prestigioses (Concern Foundation (EUA), Susan G. Komen Foundation (EUA)). Recentment, ha rebut una ERC Consolidator Grant de la Uni\u00f3 Europea adre\u00e7ada a la Dra. Gonz\u00e1lez Su\u00e1rez.<\/p>\n<p>El grup tamb\u00e9 ha signat contractes amb la ind\u00fastria i coordina assaigs cl\u00ednics de fase inicial.<\/p>\n<p>&nbsp;<\/p>\nReferencia: 682935<br \/>\nT\u00edtulo: PLEIO-RANK: Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity<br \/>\nFinanciador: ERC &#8211; H2020<br \/>\nAgradecimiento: European Research Council (ERC) under the European Union&#8217;s Horizon 2020 research and innovation program\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/investigacion.unal.edu.co\/fileadmin\/recursos\/siun\/img\/boletin\/imagenes\/logos-genericos\/erc-generico.jpg\" alt=\"\" width=\"510\" height=\"361\" \/><\/p>\n<p>&nbsp;<\/p>\nReferencia: SLT006\/17\/00122<br \/>\nTipo: &#8220;CONTRACTES D&#8217;INCORPORACI\u00d3 DE CIENT\u00cdFICS I TECN\u00d2LEGS ALS GRUPS DE RECERCA&#8221;<br \/>\nFinanciador: DEPARTAMENT DE SALUT<br \/>\nAgradecimiento: Departament de Salut de la Generalitat de Catalunya mitjan\u00e7ant l&#8217;Acci\u00f3 instrumental d&#8217;incorporaci\u00f3 (PERIS).\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.vectorlogo.es\/wp-content\/uploads\/2014\/12\/logo-vector-generalitat-catalunya.jpg\" alt=\"\" width=\"386\" height=\"196\" \/><\/p>\n<p>&nbsp;<\/p>\nReferencia: BES-2015-071675<br \/>\nTipo: &#8220;AYUDAS PARA CONTRATOS PREDOCTORALES PARA LA FORMACI\u00d3N DE DOCTORES 2015&#8221;<br \/>\nFinanciador: Ministerio de Ciencia, Innovaci\u00f3n y Universidades<br \/>\nAgradecimiento: Ministerio de Ciencia, Innovaci\u00f3n y Universidades, perteneciente a la Agencia Estatal de Investigaci\u00f3n (AEI). Cofinanciado por el Fondo Social Europeo. FSE invierte en tu futuro\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cetmar.org\/wp-content\/uploads\/2019\/02\/Dibujo-sin-t%C3%ADtulo-1.jpg\" alt=\"\" width=\"422\" height=\"316\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.colegiomariareina.es\/wp-content\/uploads\/2016\/12\/fse.png\" alt=\"\" width=\"405\" height=\"113\" \/><\/p>\nReferencia: PRE2018-086522<br \/>\nTipo: &#8220;AYUDAS PARA CONTRATOS PREDOCTORALES PARA LA FORMACI\u00d3N DE DOCTORES 2018&#8221;<br \/>\nFinanciador: Ministerio de Ciencia, Innovaci\u00f3n y Universidades<br \/>\nAgradecimiento: Ministerio de Ciencia, Innovaci\u00f3n y Universidades, perteneciente a la Agencia Estatal de Investigaci\u00f3n (AEI). Cofinanciado por el Fondo Social Europeo. FSE invierte en tu futuro\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cetmar.org\/wp-content\/uploads\/2019\/02\/Dibujo-sin-t%C3%ADtulo-1.jpg\" alt=\"\" width=\"407\" height=\"305\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.colegiomariareina.es\/wp-content\/uploads\/2016\/12\/fse.png\" alt=\"\" width=\"380\" height=\"106\" \/><\/p>\nReferencia: IJCI-2017-31564<br \/>\nTipo: &#8220;AYUDAS JUAN DE LA CIERVA &#8211; INCORPORACION 2017&#8221;<br \/>\nFinanciador: Ministerio de Ciencia, Innovaci\u00f3n y Universidades<br \/>\nAgradecimiento: Ministerio de Ciencia, Innovaci\u00f3n y Universidades, perteneciente a la Agencia Estatal de Investigaci\u00f3n (AEI).\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cetmar.org\/wp-content\/uploads\/2019\/02\/Dibujo-sin-t%C3%ADtulo-1.jpg\" alt=\"\" width=\"380\" height=\"285\" \/><\/p>\nReferencia: FJCI-2017-31565<br \/>\nTipo: &#8220;AYUDAS JUAN DE LA CIERVA &#8211; FORMACION 2017&#8221;<br \/>\nFinanciador: Ministerio de Ciencia, Innovaci\u00f3n y Universidades<br \/>\nAgradecimiento: Ministerio de Ciencia, Innovaci\u00f3n y Universidades, perteneciente a la Agencia Estatal de Investigaci\u00f3n (AEI).\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cetmar.org\/wp-content\/uploads\/2019\/02\/Dibujo-sin-t%C3%ADtulo-1.jpg\" alt=\"\" width=\"375\" height=\"281\" \/><\/p>\n<p>&nbsp;<\/p>\nReferencia: IDEAS19093GONZ<br \/>\nT\u00edtulo: RANK, instead of RANKL, as a new therapeutic target in Triple Negative Breast Cancer<br \/>\nFinanciador: Fundaci\u00f3n Cient\u00edfica de la AECC<br \/>\nAgradecimiento: Fundaci\u00f3n Cient\u00edfica de la Asociaci\u00f3n Espa\u00f1ola Contra el C\u00e1ncer\n<p><img decoding=\"async\" src=\"https:\/\/www.fecyt.es\/sites\/default\/files\/styles\/280xn\/public\/logos\/fundaciones\/aecc.jpg?itok=JodZJBTj\" alt=\"\" \/><\/p>\n<p>&nbsp;<\/p>\nSAF2017-86117-R. New insights in RANK signaling pathway: from biology to treatment<br \/>\nPI: Gonz\u00e1lez-Su\u00e1rez, Eva<br \/>\nMinisterio de Ciencia, Innovaci\u00f3n y Universidades, perteneciente a la Agencia Estatal de Investigaci\u00f3n (AEI).\nCofinanciado por el Fondo Europeo de Desarrollo Regional. FEDER, una manera de hacer Europa. Promover el desarrollo tecnol\u00f3gico, la innovaci\u00f3n y una investigaci\u00f3n de calidad.<br \/>\n<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cetmar.org\/wp-content\/uploads\/2019\/02\/Dibujo-sin-t%C3%ADtulo-1.jpg\" alt=\"\" width=\"340\" height=\"255\" \/>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/investigacion.ucam.edu\/sites\/investigacion.ucam.edu\/files\/styles\/foto_news\/public\/news\/logofeder.png?itok=MZ0i7sfT\" alt=\"\" width=\"330\" height=\"86\" \/><\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2019\/10\/ginzalez-suarez-eva-150x150.jpg\" alt=\"Gonzalez Suarez, Eva\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"ginzalez-suarez-eva\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tGonzalez Suarez, Eva\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:egsuarez@idibell.cat\" title=\"egsuarez@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tegsuarez@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tInvestigadors principals\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2019\/10\/ginzalez-suarez-eva-150x150.jpg\" alt=\"Gonzalez Suarez, Eva\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"ginzalez-suarez-eva\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tGonzalez Suarez, Eva\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:egsuarez@idibell.cat\" title=\"egsuarez@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tegsuarez@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tENLLA\u00c7OS RELACIONATS\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.enbdc.org\/\" title=\"ENBDC\" target=\"_blank\" rel=\"noopener\">\n\t\tENBDC\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/EGlezSuarezlab\" title=\"@EGlezSuarezlab\" target=\"_blank\" rel=\"noopener\">\n\t\t@EGlezSuarezlab\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tEquip\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tCaps de grup\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tInvestigadors\/es cl\u00ednics\/ques\t\t\t\t<\/a>\n\t\t\t\t\t\tCaps de grup\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Gonzalez Suarez, Eva<\/li>\n<\/ul>\n\t\t\t\t\t\tInvestigadors\/es cl\u00ednics\/ques\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Vethencourt Casado, Andrea Carolina<\/li>\n<\/ul>\n<h2>\n\t\tNot\u00edcies relacionades\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/24619\" content=\"La Fundaci\u00f3 'la Caixa' impulsa un estudi prometedor contra el c\u00e0ncer de p\u00e0ncrees\" \/><meta itemprop=\"datePublished\" content=\"2023-11-24\" \/><meta itemprop=\"dateModified\" content=\"2023-11-24\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/11\/Rovira-Espinet-scaled.jpg\" \/><meta itemprop=\"width\" content=\"2560\" \/><meta itemprop=\"height\" content=\"1280\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2023\/11\/la-fundacio-la-caixa-impulsa-un-estudi-prometedor-contra-el-cancer-de-pancrees\/\" title=\"La Fundaci\u00f3 'la Caixa' impulsa un 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podrien beneficiar-se del tractament amb Denosumab\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2023\/03\/investigadores-de-lidibell-i-el-cnio-proposen-biomarcadors-per-seleccionar-pacients-amb-cancer-de-mama-que-podrien-beneficiar-se-del-tractament-amb-denosumab\/\" title=\"Investigadores de l&#8217;IDIBELL i el CNIO proposen biomarcadors per seleccionar pacients amb c\u00e0ncer de mama que podrien beneficiar-se del tractament amb Denosumab\">Investigadores de l&#8217;IDIBELL i el CNIO proposen biomarcadors per seleccionar pacients amb c\u00e0ncer de mama que podrien beneficiar-se del tractament amb Denosumab<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t07\/03\/2023\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/17573\" content=\"Descobreixen connexi\u00f3 entre senesc\u00e8ncia i c\u00e8l\u00b7lules mare provocada per una prote\u00efna iniciadora del c\u00e0ncer de mama\" \/><meta itemprop=\"datePublished\" content=\"2021-05-17\" \/><meta itemprop=\"dateModified\" content=\"2021-05-17\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2021\/05\/NP16-E-Gonzalez_Dev-Cell-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1418\" \/><meta itemprop=\"height\" content=\"1063\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2021\/05\/descobreixen-connexio-entre-senescencia-i-cellules-mare-provocada-per-una-proteina-iniciadora-del-cancer-de-mama\/\" title=\"Descobreixen connexi\u00f3 entre senesc\u00e8ncia i c\u00e8l\u00b7lules mare provocada per una prote\u00efna iniciadora del c\u00e0ncer de mama\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2021\/05\/descobreixen-connexio-entre-senescencia-i-cellules-mare-provocada-per-una-proteina-iniciadora-del-cancer-de-mama\/\" title=\"Descobreixen connexi\u00f3 entre senesc\u00e8ncia i c\u00e8l\u00b7lules mare provocada per una prote\u00efna iniciadora del c\u00e0ncer de mama\">Descobreixen connexi\u00f3 entre senesc\u00e8ncia i c\u00e8l\u00b7lules mare provocada per una prote\u00efna iniciadora del c\u00e0ncer de mama<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t17\/05\/2021\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/16341\" content=\"Els models animals de xenograf recapitulen el comportament gen\u00e8tic dels tumors humans originals\" \/><meta itemprop=\"datePublished\" content=\"2021-01-28\" \/><meta itemprop=\"dateModified\" content=\"2021-02-02\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2021\/01\/NO01-NatGen-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2021\/01\/els-models-animals-de-xenograf-recapitulen-el-comportament-genetic-dels-tumors-humans-originals\/\" title=\"Els models animals de xenograf recapitulen el comportament gen\u00e8tic dels tumors humans originals\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2021\/01\/els-models-animals-de-xenograf-recapitulen-el-comportament-genetic-dels-tumors-humans-originals\/\" title=\"Els models animals de xenograf recapitulen el comportament gen\u00e8tic dels tumors humans originals\">Els models animals de xenograf recapitulen el comportament gen\u00e8tic dels tumors humans originals<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t28\/01\/2021\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/16019\" content=\"Descobreixen l&#8217;activitat immunomoduladora d&#8217;un f\u00e0rmac que milloraria l&#8217;efic\u00e0cia de la immunoter\u00e0pia contra el c\u00e0ncer de mama\" \/><meta itemprop=\"datePublished\" content=\"2020-12-10\" \/><meta itemprop=\"dateModified\" content=\"2020-12-10\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/12\/20201209_141133.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2020\/12\/descobreixen-lactivitat-immunomoduladora-dun-farmac-que-milloraria-leficacia-de-la-immunoterapia-contra-el-cancer-de-mama\/\" title=\"Descobreixen l&#8217;activitat immunomoduladora d&#8217;un f\u00e0rmac que milloraria l&#8217;efic\u00e0cia de la immunoter\u00e0pia contra el c\u00e0ncer de mama\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2020\/12\/descobreixen-lactivitat-immunomoduladora-dun-farmac-que-milloraria-leficacia-de-la-immunoterapia-contra-el-cancer-de-mama\/\" title=\"Descobreixen l&#8217;activitat immunomoduladora d&#8217;un f\u00e0rmac que milloraria l&#8217;efic\u00e0cia de la immunoter\u00e0pia contra el c\u00e0ncer de mama\">Descobreixen l&#8217;activitat immunomoduladora d&#8217;un f\u00e0rmac que milloraria l&#8217;efic\u00e0cia de la immunoter\u00e0pia contra el c\u00e0ncer de mama<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t10\/12\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/13531\" content=\"Troben caracter\u00edstiques immunes comunes en les met\u00e0stasis de pulm\u00f3 a les que dirigir futurs tractaments\" \/><meta itemprop=\"datePublished\" content=\"2020-07-17\" \/><meta itemprop=\"dateModified\" content=\"2021-11-15\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/07\/PADO-foto-grup-scaled.jpg\" \/><meta itemprop=\"width\" content=\"2560\" \/><meta itemprop=\"height\" content=\"1920\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2020\/07\/troben-caracteristiques-immunes-comunes-en-les-metastasis-de-pulmo-a-les-que-dirigir-futurs-tractaments\/\" title=\"Troben caracter\u00edstiques immunes comunes en les met\u00e0stasis de pulm\u00f3 a les que dirigir futurs tractaments\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2020\/07\/troben-caracteristiques-immunes-comunes-en-les-metastasis-de-pulmo-a-les-que-dirigir-futurs-tractaments\/\" title=\"Troben caracter\u00edstiques immunes comunes en les met\u00e0stasis de pulm\u00f3 a les que dirigir futurs tractaments\">Troben caracter\u00edstiques immunes comunes en les met\u00e0stasis de pulm\u00f3 a les que dirigir futurs tractaments<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t17\/07\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/7402\" content=\"La Marat\u00f3 impulsa 43 projectes sobre el c\u00e0ncer en la inversi\u00f3 anual en recerca m\u00e9s gran de la seva hist\u00f2ria\" \/><meta itemprop=\"datePublished\" content=\"2019-10-31\" \/><meta itemprop=\"dateModified\" content=\"2021-11-15\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/05\/lliurament_dajudes_a_la_recerca_en_cancer_2.jpg\" \/><meta itemprop=\"width\" content=\"1920\" \/><meta itemprop=\"height\" content=\"1280\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/10\/la-marato-impulsa-43-projectes-sobre-el-cancer-en-la-inversio-anual-en-recerca-mes-gran-de-la-seva-historia\/\" title=\"La Marat\u00f3 impulsa 43 projectes sobre el c\u00e0ncer en la inversi\u00f3 anual en recerca m\u00e9s gran de la seva hist\u00f2ria\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/10\/la-marato-impulsa-43-projectes-sobre-el-cancer-en-la-inversio-anual-en-recerca-mes-gran-de-la-seva-historia\/\" title=\"La Marat\u00f3 impulsa 43 projectes sobre el c\u00e0ncer en la inversi\u00f3 anual en recerca m\u00e9s gran de la seva hist\u00f2ria\">La Marat\u00f3 impulsa 43 projectes sobre el c\u00e0ncer en la inversi\u00f3 anual en recerca m\u00e9s gran de la seva hist\u00f2ria<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t31\/10\/2019\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/7422\" content=\"David Llobet i Eva Gonz\u00e1lez Su\u00e1rez reben ajuts de l&#8217;AECC en el Dia Mundial de la Investigaci\u00f3 del C\u00e0ncer\" \/><meta itemprop=\"datePublished\" content=\"2019-09-24\" \/><meta itemprop=\"dateModified\" content=\"2020-05-13\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/05\/efou6jzxoaaohib.jpg\" \/><meta itemprop=\"width\" content=\"680\" \/><meta itemprop=\"height\" content=\"510\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/09\/david-llobet-i-eva-gonzalez-suarez-reben-ajuts-de-laecc-en-el-dia-mundial-de-la-investigacio-del-cancer\/\" title=\"David Llobet i Eva Gonz\u00e1lez Su\u00e1rez reben ajuts de l&#8217;AECC en el Dia Mundial de la Investigaci\u00f3 del C\u00e0ncer\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/09\/david-llobet-i-eva-gonzalez-suarez-reben-ajuts-de-laecc-en-el-dia-mundial-de-la-investigacio-del-cancer\/\" title=\"David Llobet i Eva Gonz\u00e1lez Su\u00e1rez reben ajuts de l&#8217;AECC en el Dia Mundial de la Investigaci\u00f3 del C\u00e0ncer\">David Llobet i Eva Gonz\u00e1lez Su\u00e1rez reben ajuts de l&#8217;AECC en el Dia Mundial de la Investigaci\u00f3 del C\u00e0ncer<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t24\/09\/2019\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/7444\" content=\"Investigadors de l&#8217;IDIBELL confirmen la validesa dels models xenografts per als estudis de metilaci\u00f3 i quimioresist\u00e8ncia en c\u00e0ncer de mama\" \/><meta itemprop=\"datePublished\" content=\"2019-07-18\" \/><meta itemprop=\"dateModified\" content=\"2020-05-13\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/04\/heatmap_egs.jpg\" \/><meta itemprop=\"width\" content=\"1654\" \/><meta itemprop=\"height\" content=\"1384\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/07\/investigadors-de-lidibell-confirmen-la-validesa-dels-models-xenografts-per-als-estudis-de-metilacio-i-quimioresistencia-en-cancer-de-mama\/\" title=\"Investigadors de l&#8217;IDIBELL confirmen la validesa dels models xenografts per als estudis de metilaci\u00f3 i quimioresist\u00e8ncia en c\u00e0ncer de mama\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/07\/investigadors-de-lidibell-confirmen-la-validesa-dels-models-xenografts-per-als-estudis-de-metilacio-i-quimioresistencia-en-cancer-de-mama\/\" title=\"Investigadors de l&#8217;IDIBELL confirmen la validesa dels models xenografts per als estudis de metilaci\u00f3 i quimioresist\u00e8ncia en c\u00e0ncer de mama\">Investigadors de l&#8217;IDIBELL confirmen la validesa dels models xenografts per als estudis de metilaci\u00f3 i quimioresist\u00e8ncia en c\u00e0ncer de mama<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t18\/07\/2019\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/7460\" content=\"Investigadors de l'IDIBELL relacionen l'amplificaci\u00f3 d'una regi\u00f3 cromos\u00f2mica amb la resist\u00e8ncia a un medicament quimioter\u00e0pic en c\u00e0ncer de mama\" \/><meta itemprop=\"datePublished\" content=\"2019-06-18\" \/><meta itemprop=\"dateModified\" content=\"2020-05-28\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2023\/03\/cropped-Marca-B.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/wp-content\/uploads\/2020\/05\/jorge_gomez_miragaya_y_eva_gonzalez_suarez.jpg\" \/><meta itemprop=\"width\" content=\"556\" \/><meta itemprop=\"height\" content=\"515\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/06\/investigadors-de-lidibell-relacionen-lamplificacio-duna-regio-cromosomica-amb-la-resistencia-a-un-medicament-quimioterapic-en-cancer-de-mama\/\" title=\"Investigadors de l'IDIBELL relacionen l'amplificaci\u00f3 d'una regi\u00f3 cromos\u00f2mica amb la resist\u00e8ncia a un medicament quimioter\u00e0pic en c\u00e0ncer de mama\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/2019\/06\/investigadors-de-lidibell-relacionen-lamplificacio-duna-regio-cromosomica-amb-la-resistencia-a-un-medicament-quimioterapic-en-cancer-de-mama\/\" title=\"Investigadors de l'IDIBELL relacionen l'amplificaci\u00f3 d'una regi\u00f3 cromos\u00f2mica amb la resist\u00e8ncia a un medicament quimioter\u00e0pic en c\u00e0ncer de mama\">Investigadors de l&#8217;IDIBELL relacionen l&#8217;amplificaci\u00f3 d&#8217;una regi\u00f3 cromos\u00f2mica amb la resist\u00e8ncia a un medicament quimioter\u00e0pic en c\u00e0ncer de mama<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t18\/06\/2019\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Transformaci\u00f3 i met\u00e0stasi Resum La recerca del grup t\u00e9 com a objectiu identificar noves dianes terap\u00e8utiques per al c\u00e0ncer que es puguin traduir directament en estrat\u00e8gies efectives de prevenci\u00f3 o tractament. 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