{"id":2137,"date":"2019-10-02T00:58:47","date_gmt":"2019-10-01T22:58:47","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2137"},"modified":"2024-01-11T08:50:28","modified_gmt":"2024-01-11T07:50:28","slug":"bases-cel%c2%b7lulars-i-moleculars-dels-trastorns-sensorials","status":"publish","type":"page","link":"https:\/\/idibell.cat\/recerca\/area-de-neurociencies\/programa-de-neurociencies\/bases-cel%c2%b7lulars-i-moleculars-dels-trastorns-sensorials\/","title":{"rendered":"Bases cel\u00b7lulars i moleculars dels trastorns sensorials"},"content":{"rendered":"\n
El grup afronta els reptes de curar els trastorns sensorials i preservar les funcions sensorials durant l’envelliment mitjan\u00e7ant l’estudi de models animals originals en sistema vestibular i retina. El grup desenvolupa models que permeten l’obtenci\u00f3 d’informaci\u00f3 amb rellev\u00e0ncia terap\u00e8utica sobre aquests sistemes sensorials tan complexos gr\u00e0cies a la utilitzaci\u00f3 de metodologies de primera l\u00ednia, com la microsc\u00f2pia de fluoresc\u00e8ncia de super-resoluci\u00f3, el RNA-seq, o la prote\u00f2mica.<\/p>\n
Barrallo Gimeno A, Llorens J. Hair cell toxicology: With the help of a little fish<\/strong>. Front. Cell. Dev. Biol. 2022;10doi:10.3389\/fcell.2022.1085225.<\/p>\n Garg G, Finger PT, Kivel\u00e4 TT, Simpson ER, Gallie BL, Saakyan S, Amiryan AG, Valskiy V, Chin KJ, Semenova E, Seregard S, Fil\u00ec M, Wilson M, Haik B, Caminal JM, Catala Mora J, Guti\u00e9rrez C, Pelayes DE, Folgar AM, Jager MJ, Dogrus\u00f6z M, Luyten GPM, Singh AD, Suzuki S, AJCC Ophthalmic Oncology Task F. Patients presenting with metastases: stage IV uveal melanoma, an international study<\/strong>. Br J Ophthalmol. 2022;106(4):510-517. doi:10.1136\/bjophthalmol-2020-317949.<\/p>\n Caminal JM, Lorenzo D, Gutierrez C, Slocker A, Piulats JM, Cobos E, Garcia Bru P, Morwani R, Santamaria JF, Arias L. Local Resection in Choroidal Melanoma: A Review<\/strong>. J. Clin. Med. 2022;11(23):doi:10.3390\/jcm11237156.<\/p>\n Garcia Tornel A, Millan M, Rubiera M, Bustamante A, Requena M, Dorado L, Oliv\u00e9 Gadea M, Jim\u00e9nez X, Soto A, Querol M, Hern\u00e1ndez P\u00e9rez M, Gomis M, Cardona P, Urra X, Purroy F, Silva Y, Ustrell X, Esteve P, Salvat Plana M, Gallofr\u00e9 M, Molina C, D\u00e1valos A, Jovin T, Abilleira S, Ribo M, P\u00e9rez de la Ossa N, RACECAT Trial I. Workflows and Outcomes in Patients With Suspected Large Vessel Occlusion Stroke Triaged in Urban and Nonurban Areas<\/strong>. Stroke. 2022;doi:10.1161\/STROKEAHA.122.040768.<\/p>\n Gabrielle PH, Nguyen V, Arnould L, Viola F, Zarranz Ventura J, Barthelmes D, Creuzot Garcher C, Gillies M, Fight Retinal Blindness! Study G. Incidence, Risk Factors, and Outcomes of Rhegmatogenous Retinal Detachment after Intravitreal Injections of Anti-VEGF for Retinal Diseases: Data from the Fight Retinal Blindness! Registry<\/strong>. Ophthalmol Retina. 2022;6(11):1044-1053. doi:10.1016\/j.oret.2022.05.008.<\/p>\n\t\t\t\t\tProjectes seleccionats<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t PUB22015. Aplicaci\u00f3 de noves tecnologies moleculars en el diagn\u00f2stic gen\u00e8tic de les distr\u00f2fies heredit\u00e0ries de retina<\/strong>. Hospital Universitario de Bellvitge. Budget: 20000. 2022-2025. PI: Cobos Mart\u00edn, Estefan\u00eda.<\/p>\n2022-222-1. RETROSPECTIVE CHART REVIEW STUDY COMBINED WITH CROSS-SECTIONAL PATIENT AND CAREGIVER SURVEYS TO DOCUMENT AND DESCRIBE THE DISEASE-RELATED CLINICAL, INDIVIDUAL, SOCIO-DEMOGRAPHIC CHARACTERISTICS OF PATIENTS WITH X-LINKED RETINITIS PIGMENTOSA (XLRP) AND THE IMPACT OF XLRP ON PATIENTS AND THEIR CAREGIVERS<\/strong>. PCI2020-120681-2. Vestibular loss and spatial orientation<\/strong>. ERA-NET Neuron (Agencia Estatal de Investigaci\u00f3n). Budget: 150000. 2021-2024. PI: Llorens Baucells, Jordi.<\/p>\n PID2021-124678OB-I00. New molecular mechanisms in chronic vestibular damage<\/strong>. Agencia Estatal de Investigaci\u00f3n. Budget: 96800. 2022-2025. PI: Llorens Baucells, Jordi i Barrallo Gimeno, Alejandro.<\/p>\n PID2020-115431RB-I00. Retinal adaptation to light and pan-disease therapeutic targets in inherited blindness: IMPDH1 and energy metabolism<\/strong>. Agencia Estatal de Investigaci\u00f3n. Budget: 120000. 2021-2024. PI: M\u00e9ndez Zunzunegui, Ana.<\/p>\n 202007-30-31. A patient centered research: awareness of patient needs, clinical phenotyping and molecular parthenogenesis in Neurofibromatosis type 2<\/strong>. Fundaci\u00f3 La Marat\u00f3 de TV3. Budget: 142485,90. 2021-2024. PI: Llorens Baucells, Jordi.<\/p>\n\t\t\t\t\tM\u00e9s informaci\u00f3<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tIdentificaci\u00f3 de nitrils com a nova fam\u00edlia de compostos amb toxicitat vestibular. <\/p>\n Bases cel\u00b7lulars i moleculars dels trastorns sensorials Resum El grup afronta els reptes de curar els trastorns sensorials i preservar les funcions sensorials durant l’envelliment mitjan\u00e7ant l’estudi de models animals originals en sistema vestibular i retina. El grup desenvolupa models que permeten l’obtenci\u00f3 d’informaci\u00f3 amb rellev\u00e0ncia terap\u00e8utica sobre aquests sistemes sensorials tan complexos gr\u00e0cies a […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":503,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"publishpress_future_action":{"enabled":false,"date":"2024-05-12 04:16:12","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/2137"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=2137"}],"version-history":[{"count":5,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/2137\/revisions"}],"predecessor-version":[{"id":24855,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/2137\/revisions\/24855"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/503"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=2137"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n(EXPLORE XLRP 2 ). Budget: 7850. 2022- . PI: Cobos Mart\u00edn, Estefan\u00eda.\n
\nModels animals de base per a l’ablaci\u00f3 de c\u00e8l\u00b7lules capil\u00b7lars en el sistema vestibular del ratol\u00ed.
\nIdentificaci\u00f3 del desacoblament sin\u00e0ptic i extrusi\u00f3 de c\u00e8l\u00b7lules capilars com a principals esdeveniments en la toxicitat vestibular cr\u00f2nica.
\nCaracteritzaci\u00f3 del paper de les prote\u00efnes GCAP en la respostes lleugeres.
\nIdentificaci\u00f3 de GCAP2 com a mediador de danys lleugers, involucrats en la fisiopatologia dels trastorns gen\u00e8tics “lleugers”.\n\t\t\t\t\n\n\t\tLlorens Baucells, Jordi\n\t<\/h4>\n
\n\t\t\n\t\tjllorens@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tInvestigadors principals\n\t<\/h2>\n\t\t\t\t\n
\n\t\tLlorens Baucells, Jordi\n\t<\/h4>\n
\n\t\t\n\t\tjllorens@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t\n
\n\t\tMendez Zunzunegui, Ana\n\t<\/h4>\n
\n\t\t\n\t\tmendezzu@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t\n
\n\t\tBarrallo Gimeno, Alejandro\n\t<\/h4>\n
\n\t\t\n\t\tabarrallo@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t\n
\n\t\tCatala Mora, Jaume \n\t<\/h4>\n
\n\t\tENLLA\u00c7OS RELACIONATS\n\t<\/h4>\n
\n\t\t\n\t\tInstitut de Neuroci\u00e8ncies UB\n\t\t<\/a>\n\t<\/h4>\n
\n\t\t\n\t\t@UBneuroscience\n\t\t<\/a>\n\t<\/h4>\n
\n\t\t\n\t\t@JordiLlorensUB\n\t\t<\/a>\n\t<\/h4>\n
\n\t\t\n\t\t@alexbarrallo\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tEquip\n\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\tCaps de grup\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tInvestigadors\/es principals\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tInvestigadors\/es cl\u00ednic\/ques\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tInvestigadors\/es postdoctorals\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tInvestigadors\/es predoctorals\t\t\t\t<\/a>\n\t\t\t\t\t\tCaps de grup\n\t\t\t\t\t\t\t\t\t\t\t
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\n\t\tNot\u00edcies relacionades\n\t<\/h2>\n\t\t\n\t\t\t\t<\/a>\n\t\t\tDescriuen les vies de regulaci\u00f3 d’un enzim clau en l’excitaci\u00f3 de les c\u00e8l\u00b7lules fotoreceptores de la retina<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t24\/04\/2020\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tIdentifiquen la prote\u00efna responsable de la mort cel\u00b7lular causant d’un tipus de ceguera<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t13\/02\/2020\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tL’ICFO i l’IDIBELL, junts en nous projectes<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t29\/02\/2016\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tDeterminen les causes moleculars de la recuperaci\u00f3 del sentit de l’equilibri en casos d’ototoxicitat<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t06\/10\/2015\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tL’ONCE i l’IDIBELL col\u2022laboren en un projecte sobre ceguesa heredit\u00e0ria<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t19\/03\/2015\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tLa Fundaci\u00f3 Ramon Areces finan\u00e7a un projecte sobre ceguera heredit\u00e0ria de l’IDIBELL<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t09\/02\/2015\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tDescriuen un mecanisme rellevant en certs tipus de ceguesa heredit\u00e0ria<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t25\/07\/2014\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tL’ONCE i l’IDIBELL col\u00b7laboren en un projecte sobre ceguesa heredit\u00e0ria<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t05\/03\/2014\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tLa intoxicaci\u00f3 per compostos industrials pot provocar efectes similars a l’ELA<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t17\/07\/2012\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tJordi Llorens nomenat president de la International Neurotoxicology Association<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t20\/06\/2011\t\t\t\t\t\t\t\n\t\t\n\n","protected":false},"excerpt":{"rendered":"