{"id":12824,"date":"2020-05-21T16:51:04","date_gmt":"2020-05-21T14:51:04","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=12824"},"modified":"2024-09-03T13:40:27","modified_gmt":"2024-09-03T11:40:27","slug":"regeneracio-del-pancrees-progenitors-pancreatics-i-els-seus-ninxols","status":"publish","type":"page","link":"https:\/\/idibell.cat\/recerca\/area-medicina-regenerativa\/programa-de-medicina-regenerativa\/regeneracio-del-pancrees-progenitors-pancreatics-i-els-seus-ninxols\/","title":{"rendered":"Regeneraci\u00f3 del p\u00e0ncrees: progenitors pancre\u00e0tics i els seus n\u00ednxols"},"content":{"rendered":"\n
La diabetis tipus 1 est\u00e0 causada per una destrucci\u00f3 autoimmune de les c\u00e8l\u00b7lules \u03b2 pancre\u00e0tiques. Aquestes c\u00e8l\u00b7lules s\u00f3n la font de la insulina, una hormona necess\u00e0ria per a la regulaci\u00f3 dels nivells de glucosa a la sang. Un enfocament per recuperar l’home\u00f2stasi de la glucosa seria induir la restauraci\u00f3 de la massa de c\u00e8l\u00b7lules \u03b2, ja sigui mitjan\u00e7ant el reempla\u00e7ament amb c\u00e8l\u00b7lules ex\u00f2genes o mitjan\u00e7ant la regeneraci\u00f3 de progenitors end\u00f2gens, per\u00f2 l’exist\u00e8ncia d’aquests progenitors \u00e9s encara controvertida. El grup de Rovira se centra en el paper de les c\u00e8l\u00b7lules ductals com progenitors pancre\u00e0tics per desenvolupar noves ter\u00e0pies per al tractament de la diabetis. D’altra banda, el laboratori tamb\u00e9 est\u00e0 estudiant el n\u00ednxol requerit per al manteniment de l’progenitor pancre\u00e0tic.<\/p>\n
Desenvolupar ter\u00e0pies per mantenir la normoglic\u00e8mia en pacients diab\u00e8tics per evitar o reduir les complicacions de la diabetis tipus 1.<\/p>\n
Desenvolupar ter\u00e0pies regeneratives en diabetis humana, ja sigui mitjan\u00e7ant la manipulaci\u00f3 de teixit exocr\u00ed pancre\u00e0tic de donants in vitro<\/em> i la seva posterior trasplantament, o mitjan\u00e7ant la manipulaci\u00f3 in vivo<\/em> o in vitro<\/em> de les c\u00e8l\u00b7lules del conducte pancre\u00e0tic dels pacients.<\/p>\n\t\t\t\t\tPublicacions seleccionades<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t Regeneraci\u00f3 del p\u00e0ncrees: progenitors pancre\u00e0tics i els seus n\u00ednxols Resum La diabetis tipus 1 est\u00e0 causada per una destrucci\u00f3 autoimmune de les c\u00e8l\u00b7lules \u03b2 pancre\u00e0tiques. Aquestes c\u00e8l\u00b7lules s\u00f3n la font de la insulina, una hormona necess\u00e0ria per a la regulaci\u00f3 dels nivells de glucosa a la sang. Un enfocament per recuperar l’home\u00f2stasi de la glucosa […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":3924,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-12824","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2024-12-25 05:38:42","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/12824","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/comments?post=12824"}],"version-history":[{"count":8,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/12824\/revisions"}],"predecessor-version":[{"id":26242,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/12824\/revisions\/26242"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/pages\/3924"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=12824"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\n
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\n\t\tRovira Clusellas, Meritxell\n\t<\/h4>\n
\n\t\t\n\t\tRovira Clusellas, Meritxell\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tInvestigadors principals\n\t<\/h2>\n\t\t\t\t\n
\n\t\tRovira Clusellas, Meritxell\n\t<\/h4>\n
\n\t\t\n\t\tRovira Clusellas, Meritxell\n\t\t<\/a>\n\t<\/h4>\n
\n\t\t ENLLA\u00c7OS RELACIONATS\n\t<\/h4>\n
\n\t\t\n\t\t@LabRovira\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tORCID\n\t<\/h4>\n
\n\t\tGoogle Scholar\n\t<\/h4>\n
\n\t\tEquip\n\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\tCap de grup\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tInvestigadors\/es postdoctorals\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tInvestigadors\/es predoctorals\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tSuport cient\u00edfic\t\t\t\t<\/a>\n\t\t\t\t\t\tCap de grup\n\t\t\t\t\t\t\t\t\t\t\t
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\n\t\tNot\u00edcies relacionades\n\t<\/h2>\n\t\t\n\t\t\t\t<\/a>\n\t\t\tEs descriu un mapa cel\u00b7lular del p\u00e0ncrees que ajudar\u00e0 a dissenyar millors tractaments contra el c\u00e0ncer de p\u00e0ncrees i la diabetis<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t02\/09\/2024\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tUn estudi descriu com es formen els insulinomes, un tipus rar de tumor de les c\u00e8l\u00b7lules beta del p\u00e0ncrees<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t18\/07\/2024\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tLa Dra. Meritxell Rovira, guardonada amb el premi “CRIS de Excelencia” per estudiar el c\u00e0ncer de p\u00e0ncrees<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t18\/04\/2024\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tIDIBELL rep 25.907\u20ac gr\u00e0cies a les aportacions dels clients de Bonpreu i Esclat<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t12\/12\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tLa Fundaci\u00f3 ‘la Caixa’ impulsa un estudi prometedor contra el c\u00e0ncer de p\u00e0ncrees<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t24\/11\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tBonpreu i Esclat se sumen a la lluita contra la diabetis amb una campanya solid\u00e0ria a favor de l’IDIBELL<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t07\/11\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tUn estudi descriu una nova manera de generar c\u00e8l\u00b7lules productores d’insulina<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t22\/06\/2022\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tComen\u00e7a el programa d’intercanvi entre IDIBELL i SZBL<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t06\/05\/2022\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tTanquem un 2021 ple de ci\u00e8ncia!<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t30\/12\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tL’impuls de les c\u00e8l\u00b7lules beta pancre\u00e0tiques en ratolins obre la porta a futurs tractaments per a la diabetis<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t11\/08\/2021\t\t\t\t\t\t\t\n\t\t\n\n","protected":false},"excerpt":{"rendered":"