{"id":16835,"date":"2021-03-11T17:21:31","date_gmt":"2021-03-11T16:21:31","guid":{"rendered":"https:\/\/idibell.cat\/?post_type=agenda&#038;p=16835"},"modified":"2021-03-22T08:59:31","modified_gmt":"2021-03-22T07:59:31","slug":"idibellseminars-tourette-syndrome-from-a-computational-perspective","status":"publish","type":"agenda","link":"https:\/\/idibell.cat\/agenda\/idibellseminars-tourette-syndrome-from-a-computational-perspective\/","title":{"rendered":"#IDIBELLseminars: Tourette syndrome from a computational perspective"},"content":{"rendered":"<p><strong>Vasco Concei\u00e7ao<\/strong><br \/>\nUniversity of Lisbon, Portugal<\/p>\n<p>Tourette syndrome (TS) is a neuropsychiatric disorder that is characterized by the manifestation of motor and phonic tics, which are often preceded by premonitory urges, uncomfortable sensations that typically precede and are ceased by tics. Tourette syndrome has an estimated prevalence of 1% in children and adolescents, but its etiology and pathophysiology are still not well-understood, which helps to explain why there are still fundamental questions about the best treatment options for patients with TS. In this talk, I will address those issues by showing how dopaminergic hyperinnervation may be causally implicated in (premonitory-urge-driven) tic learning and expression in TS, as well as how tic learning and expression may be attenuated by standard pharmacological treatments of TS, using biologically inspired reinforcement-learning models.<\/p>\n<p><em>Hosted by Carles Soriano-Mas<\/em><\/p>\n","protected":false},"featured_media":16836,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"tags":[506],"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/agenda\/16835"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/agenda"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/agenda"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media\/16836"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=16835"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=16835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}