{"id":14715,"date":"2020-09-21T13:41:00","date_gmt":"2020-09-21T11:41:00","guid":{"rendered":"https:\/\/idibell.cat\/?post_type=agenda&#038;p=14715"},"modified":"2020-10-06T10:27:07","modified_gmt":"2020-10-06T08:27:07","slug":"idibellconnect-novel-clinical-and-translational-research-approaches-to-mesothelioma-an-orphan-tumor-catala","status":"publish","type":"agenda","link":"https:\/\/idibell.cat\/agenda\/idibellconnect-novel-clinical-and-translational-research-approaches-to-mesothelioma-an-orphan-tumor-catala\/","title":{"rendered":"#IDIBELLconnect: Novel clinical and translational research approaches to mesothelioma, an orphan tumor"},"content":{"rendered":"<p>Mesothelioma is a rare and aggressive tumor with dismal prognosis arising in the pleura and associated with asbestos exposure. Its incidence is on the rise worldwide. In patients with advanced MPM, chemotherapy is the standard of care. Currently, no standard salvage therapy has been approved in the last decades. Novel therapeutic approaches are urgently needed. During the seminar, I will give an overview on the lines of research that are currently ongoing in our group consisting on i) Characterization of the immune TME of mesothelioma to unravel novel immunotherapeutic approaches and identify potential biomarkers; ii) Assessment of the antitumor activity of CDK4\/6 inhibitors in preclinical models of mesothelioma; iii) Testing of germline and somatic alterations in a prospective cohort of mesothelioma patients. The clinical trials conducted in mesothelioma at IDIBELL will be discussed.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"tags":[78],"_links":{"self":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/agenda\/14715"}],"collection":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/agenda"}],"about":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/types\/agenda"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/media?parent=14715"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/wp-json\/wp\/v2\/tags?post=14715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}