The global aim of EUCANCan project is to build a network of Personalized Medicine nodes that enables and promotes the generation, exchange and sharing of harmonized and high-quality genomic and clinical data. This offer is supported by the European Union’s Horizon 2020 research and innovation programme under grant agreement No 825835.
IDIBELL is a research center that integrates the biomedical research of the Bellvitge University Hospital (HUB), the Catalan Institute of Oncology (ICO), and the University of Barcelona in the Bellvitge Campus (UB) and the Viladecans Hospital (HV), located in south Barcelona.
The research focuses of IDIBELL are cancer, neuroscience and translational medicine; research, innovation and society are the pivots on which researchers work every day in order to improve the quality of life of citizens.
IDIBELL is located in L’Hospitalet de Llobregat, south of Barcelona. It is a member of the Campus of International Excellence of the University of Barcelona HUBc and part of the CERCA institution of the Generalitat of Catalonia. In 2009, it became one of the first five Spanish research centers accredited as a health research institute by the Carlos III Institute of Health. More recently, the European Commission has recognized IDIBELL with the HRS4R logo (Excellence in Human Resources in Research), which identifies IDIBELL as a provider and supporter of a stimulating research work environment.
With the deployment of massively parallel next-generation sequencing (NGS) technologies, the identification of variants of unknown significance (VUS) in cancer predisposing genes is expanding dramatically. Our group has worked on the classification of hereditary cancer genes VUS identified in the Spanish population, pioneering the development of functional algorithms and the refinement of gene-specific classification guidelines. There is a real need to build resources that facilitate the interpretation and classification of VUS taking into account geographical genetic specificities. Data storage and data sharing, both at the national and international level, are critical to effectively mine the huge amounts of information obtained during genetic testing.
We are seeking for a database software engineer / full-stack developer who will implement a project aimed at creating a national registry of genetic variants in cancer predisposing genes that could be useful for their interpretation. To address this issue, the candidate will be responsible for the design and development of a web-based platform, including the whole system: front-end, back-end and a relational database of genetic variants. Specific data loading subsystems will be developed for collaborator groups allowing for partial automation. Loaded variants will be annotated using a bioinformatic pipeline. The system will have a variant classification module to help data curators evaluate pathogenicity. Finally, the necessary mechanisms to push the variants to international variant databases will be implemented.
The candidate will have the opportunity to work within the Hereditary Cancer Group at IDIBELL (www.idibell.cat/en/content/hereditary-cancer) under the supervision of Dr. Gabriel Capellá and Conxi Lázaro.
The overarching goal of the Hereditary Cancer Group at IDIBELL is to gain insight into the molecular basis of hereditary cancer, to personalize risk assessment to patients and relatives, as well as to individualize management regarding follow-up, treatment and prophylactic measures. Our multidisciplinary group includes basic researchers, clinicians, bioinformaticians, genetic counselors in familial cancer and laboratory technicians, facilitating fully comprehensive studies, data analysis, access to the patients and samples, and the translation of the obtained results to the clinics and genetic counseling.
Successful candidates will join a dynamic, young and well-equipped research group with strong interactions and multidisciplinary research. The group offers a stimulating research atmosphere and an environment in which collaboration and exchange of ideas and techniques is actively encouraged with a strong commitment to research which provides a lively and stimulating environment for young talents.
- Education: Computer science or related degree.
- Experience: The applicant must have at least 2 years of work experience as full-stack developer (front-end, back-end, and database). Experience in multiple programming languages is also required. Knowledge or working experience about genetics and NGS pipelines will be essential.
- Languages: English proficiency.
- Technical skills: Good working knowledge of Linux. Experience dealing with sensible data and knowledge of security best practices. Fluent in R programming. Soft skills:
- Excellent communication skills, both written and oral, and ability to collaborate with team members.
- Excellent organizational skills.
- Ability to work independently as well as part of a team.
3-5 years of working experience as full-stack developer.
Working experience in Django web framework and PostgreSQL.
Any participation in research projects, co-authorship in publications and mobility experience will be considered as a valuable contribution.
- Type of contract: Temporary (1 year)
- Workday: Full-time, 40h / week
- Working hours: Monday to Friday, flexible schedule
- Professional Category: Informatic Technician B
- Salary: According to IDIBELL salary tables
- Job location: IDIBELL laboratory
- Incorporation: January 1st, 2021
- Other: “This contract is supported by the National Cancer Institute of the National Institutes of Health under Award Number R01CA218342.”
- Curriculum Vitae
- Cover Letter
Deadline for sending CVs will be next November 30th, 2020.
All job profiles must be reviewed and accepted by the HR Department in order to guarantee legal and labor compliance, and the principles of the European charter for Researchers and the Code of Conduct for the Recruitment Researchers.
IDIBELL obtained the seal of Excellence in HR in 2015
This seal represents IDIBELL’s commitment to the implementation of HR policies, which oversee the attracting and development of talent in an open, transparent manner, based on personal merit, aligned with the principles of the European charter for Researchers and the Code of Conduct for the Recruitment Researchers.