Research at the Plass Group aims at understanding how RNA binding proteins (RBPs) regulate gene expression and how perturbations in these RBPs contribute to the development of neurodegenerative diseases. For this purpose, we use a combination of molecular biology approaches with high-throughput sequencing technologies and computational analyses. Using iPSC based modelling and single-cell transcriptomics, we study how RBPs contribute to cell differentiation and how the transcriptomic networks regulated by these RBPs are altered in the development of neurodegenerative disease.
We are looking for a highly skilled and motivated PhD student to join our team. The successful candidate will develop new computational tools and analyses to characterize the function of RBPs in single-cell transcriptomics data and their impact on cell differentiation.
- Background in Biology, Bioinformatics, Genomics, Computer Science, Physics, or a related field
- Strong programming skills (e.g. R, Python, Bash)
- Good technical skills including bioinformatics, linux, data analysis and statistics
- Desire to engage in multidisciplinary projects and develop computational analyses to answer biological questions
- Fluency in spoken and written English
We will value:
Prior experience with single-cell transcriptomics, high-throughput sequencing and method development are desirable.
We offer a four-year PhD contract. The successful applicant will join the Gene regulation of cell identity group led by Dr. Plass. The Plass Group offers a highly dynamic, multi-national, and intellectually stimulating working environment and state-of-the-art research facilities and support for continuous learning. Together with Dr. Plass, the successful candidate with define its own PhD project in one of the topics relevant for the research in the lab. The candidate will have the possibility of publishing his/her work in high-impact journals and present it in national and international conferences.
- Cover Letter
- Curriculum vitae
- Two reference letters
Deadline for sending CVs will be next July, 15
All job profiles must be reviewed and accepted by the HR Department in order to guarantee legal and labor compliance, and the principles of the European charter for Researchers and the Code of Conduct for the Recruitment Researchers.
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