{"id":13224,"date":"2020-05-08T13:00:06","date_gmt":"2020-05-08T11:00:06","guid":{"rendered":"https:\/\/idibell.cat\/es\/?p=13224"},"modified":"2020-05-19T08:13:58","modified_gmt":"2020-05-19T06:13:58","slug":"un-estudio-con-participacion-del-idibell-determina-el-numero-de-ciclos-de-quimioterapia-optimo-para-tratar-el-glioblastoma","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2020\/05\/un-estudio-con-participacion-del-idibell-determina-el-numero-de-ciclos-de-quimioterapia-optimo-para-tratar-el-glioblastoma\/","title":{"rendered":"Un estudio con participaci\u00f3n del IDIBELL determina el n\u00famero de ciclos de quimioterapia \u00f3ptimo para tratar el glioblastoma"},"content":{"rendered":"<div class=\"article-body\">\n<div class=\"field field-name-body field-type-text-with-summary field-label-hidden\">\n<div class=\"field-items\">\n<div class=\"field-item even\">\n<p>Actualmente, los pacientes con glioblastoma reciben seis ciclos de radiaci\u00f3n y de temozolomida, un tipo de quimioterapia oral. Sin embargo, el n\u00famero de rondas necesarias ha sido objeto de debate durante a\u00f1os. Por este motivo, un equipo formado por investigadores del Instituto Catal\u00e1n de Oncolog\u00eda (<a href=\"http:\/\/ico.gencat.cat\/es\/inici\/index.html\">ICO<\/a>), el Instituto de Investigaci\u00f3n Biom\u00e9dica de Bellvitge (<a href=\"http:\/\/www.idibell.cat\/es\">IDIBELL<\/a>) y el Instituto de Investigaci\u00f3n en Ciencias de la Salud Germans Trias i Pujol (<a href=\"http:\/\/www.germanstrias.org\/es-index\/\">IGTP<\/a>) ha llevado a cabo un ensayo cl\u00ednico con m\u00e1s de 150 pacientes con el fin de poder determinar el n\u00famero \u00f3ptimo de ciclos.<\/p>\n<p>Los resultados, publicados recientemente en la revista\u00a0<a href=\"https:\/\/academic.oup.com\/neuro-oncology\/advance-article-abstract\/doi\/10.1093\/neuonc\/noaa107\/5824410?redirectedFrom=fulltext\">Neuro Oncology<\/a>, y financiados a trav\u00e9s de una beca del Instituto Carlos III, demuestran que aumentar el n\u00famero de ciclos de este tipo de quimioterapia no aporta beneficios adicionales. Adem\u00e1s, el estudio apunta que un mayor n\u00famero de ciclos podr\u00eda ser contraproducente, ya que incrementa la toxicidad del tratamiento.<\/p>\n<p>&nbsp;<\/p>\n<h4>Una amplia participaci\u00f3n<\/h4>\n<p>&nbsp;<\/p>\n<p>El estudio, que ha durado m\u00e1s de 5 a\u00f1os, es un ensayo cl\u00ednico en fase II, multic\u00e9ntrico y abierto. Es decir, en este caso, tanto los pacientes como los profesionales eran conscientes de si recib\u00edan el tratamiento experimental, en este caso 12 ciclos de temozolomida, o si, por el contrario, recibieron s\u00f3lo los 6 ciclos que actualmente est\u00e1n establecidos en las gu\u00edas cl\u00ednicas.<\/p>\n<p>Las conclusiones, aunque no son positivas, permiten cerrar la discusi\u00f3n y por tanto asegurar que los pacientes de glioblastoma reciben el mejor tratamiento.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>El ensayo cl\u00ednico, publicado en la revista &#8216;Neuro Oncology&#8217;, demuestra que alargar el n\u00famero de ciclos de temozolomida en pacientes con este tipo de tumor no aporta beneficios adicionales e incrementa la toxicidad del tratamiento.s de temozolomida en pacients amb aquest tipus de tumor no aporta beneficis addicionals i incrementa la toxicitat del tractament.<\/p>\n","protected":false},"author":8,"featured_media":13225,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[184],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-08 15:48:47","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/13224"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=13224"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/13224\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/13225"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=13224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=13224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=13224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}