Coltheres utilizar\u00e1 los c\u00e1nceres colorectales como banco de pruebas para definir biomarcadores espec\u00edficos \u00fatiles para el dise\u00f1o de tratamientos personalizados. El consorcio est\u00e1 abierto a la posibilidad que la industria farmac\u00e9utica pueda determinar qu\u00e9 pacientes tienen m\u00e1s probabilidades de responder a sus nuevos tratamientos contra el c\u00e1ncer y realizar ensayos cl\u00ednicos r\u00e1pidos de test de concepto.
El consorcio est\u00e1 integrado por unidades cl\u00ednicas pioneras en test de biomarcadores en terapias personalizadas y grupos de investigaci\u00f3n traslacional l\u00edderes, con una trayectoria probada a la hora de desarrollar diagn\u00f3sticos para terapias contra el c\u00e1ncer. Es importante destacar que el consorcio europeo incluye dos empresas: Horizon Discovery (Reino Unido) y Agendia (Holanda). La primera desarrollar\u00e1 nuevos modelos celulares de c\u00e1ncer con nuevos biomarcadores predictivos de la respuesta farmacol\u00f3gica, determinados por los perfiles de los pacientes que proporcionen los miembros del consorcio. Por su parte, Agendia desarrollar\u00e1 pruebas para predecir la respuesta del paciente a las terapias basadas en la firma gen\u00f3mica de cada tumor.
El director del Programa de Epigen\u00e9tica y Biolog\u00eda Celular del C\u00e1ncer del IDIBELL, que participa en el consorcio, Manel Esteller, ha explicado que \u201cColtheres ha sido dise\u00f1ado para incorporar el tratamiento personalizado del c\u00e1ncer en la pr\u00e1ctica cl\u00ednica utilizando los tumores colorectales como modelo\u201d. Esteller ha mostrado su satisfacci\u00f3n por formar parte de este proyecto de la UE que cuenta con expertos internacionales en los campos de la gen\u00e9tica funcional, la epigen\u00f3mica, la farmacogen\u00e9tica y la oncolog\u00eda cl\u00ednica. Ha explicado que la aportaci\u00f3n del IDIBELL a Coltheres \u201cser\u00e1 obtener perfiles epigen\u00f3micos de los pacientes y de los modelos experimentales para encontrar nuevos biomarcadores de pron\u00f3stico y de resistencia a f\u00e1rmacos en c\u00e1ncer colorectal\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
En el consorcio Coltheres participan hospitales y centres de investigaci\u00f3n traslacional de seis pa\u00edses europeos<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[286],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-09 23:08:17","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11439"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11439"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11439\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11439"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11439"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11439"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}