El investigador Gianluigi Giannelli de la Universidad de Bari, Italia, centra su investigaci\u00f3n en el estudio de los mecanismos moleculares responsables de la progresi\u00f3n de los tumores, especialmente hep\u00e1ticos, y en la identificaci\u00f3n de nuevas dianas terap\u00e9uticas. Gianelli ha explicado en una conferencia en el marco de los seminarios Idibell, el pasado 20 de mayo, que \u00e9sta debe ser la aproximaci\u00f3n correcta en la investigaci\u00f3n de nuevas estrategias terap\u00e9uticas contra el c\u00e1ncer: \u201cA\u00fanque es m\u00e1s lento que probar varios f\u00e1rmacos con los pacientes de c\u00e1ncer, seg\u00fan su perfil gen\u00e9tico, debemos pensar que no se trata s\u00f3lo parar la expansi\u00f3n del c\u00e1ncer, debemos hacerlo evitando que el paciente sufra demasiados efectos secundarios provocados por los f\u00e1rmacos\u201d.
En este sentido Giannelli ha explicado sus avances en la investigaci\u00f3n de un f\u00e1rmaco capaz de bloquear la acci\u00f3n del TGF-B1 en la proliferaci\u00f3n del c\u00e1ncer de h\u00edgado. \u201cEn este caso\u201d explica el investigador italiano \u201chemos conseguido una \u00fanica diana, el TGF-B1, que est\u00e1 involucrada en varias v\u00edas de se\u00f1alizaci\u00f3n que activan la proliferaci\u00f3n del tumor. Con un \u00fanico f\u00e1rmaco conseguimos un efecto d\u00f3mino en el bloqueo de la expansi\u00f3n del c\u00e1ncer\u201d. Giannelli ha explicado que su grupo participar\u00e1 en los pr\u00f3ximos meses en varios ensayos cl\u00ednicos con inhibidores de TGF-B.<\/p>\n","protected":false},"excerpt":{"rendered":"
El investigador Gianluigi Giannelli de la Universidad de Bari, Italia, centra su investigaci\u00f3n en el estudio de los mecanismos moleculares responsables de la progresi\u00f3n de los tumores, especialmente hep\u00e1ticos, y en la identificaci\u00f3n de nuevas dianas terap\u00e9uticas. Gianelli ha explicado en una conferencia en el marco de los seminarios Idibell, el pasado 20 de mayo, […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[184],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-15 16:40:22","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11419"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11419"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11419\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}