{"id":11375,"date":"2011-10-28T00:00:00","date_gmt":"2011-10-27T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2011\/10\/28\/marcus-buschbeck-todavia-no-entendemos-como-se-ordena-la-biblioteca-donde-se-almacena-el-adn\/"},"modified":"2020-05-26T09:33:19","modified_gmt":"2020-05-26T07:33:19","slug":"marcus-buschbeck-todavia-no-entendemos-como-se-ordena-la-biblioteca-donde-se-almacena-el-adn","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2011\/10\/marcus-buschbeck-todavia-no-entendemos-como-se-ordena-la-biblioteca-donde-se-almacena-el-adn\/","title":{"rendered":"Marcus Buschbeck: \u201cTodav\u00eda no entendemos c\u00f3mo se ordena la biblioteca donde se almacena el ADN\u201d"},"content":{"rendered":"<p>El investigador Marcus Buschbeck del <a href=\"http:\/\/www.imppc.org\/ca\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Instituto de Medicina Predictiva y Personalizada del C\u00e1ncer<\/span><\/a> (IMPPC) de Badalona ha explicado sus \u00faltimos avnces en la investigaci\u00f3n de una prote\u00edna relacionada con el empaquetamiento del ADN y su implicaci\u00f3n en la diferenciaci\u00f3n celular el 21 de octubre dentro el ciclo de seminarios IDIBELL. <b><br \/> El objetivo del grupo de Buschbeck es entender como una c\u00e9lula cambia su fenotipo y como se regula su nivel de cromatina. Es decir c\u00f3mo se organiza y empaqueta la informaci\u00f3n del ADN. <b><br \/>Seg\u00fan el investigador, si imaginamos una biblioteca, \u201clos libros serian el ADN y la forma en que se reparten por las secciones, las mesas o el alamc\u00e9n seria la epigen\u00e9tica que hace que alguna informaci\u00f3n tenga m\u00e1s importancia que otra. Todav\u00eda no entendemos la estructura de la biblioteca\u201d. <b><br \/> Para entenderla mejor estudian la variante de histona MacroH2A y han visto que est\u00e1 implicada en la diferenciaci\u00f3n celular \u201cno s\u00f3lo en el desarrollo embrionario sino tambi\u00e9n en tejidos ya existentes, de forma que podr\u00eda tener un papel en el desarrollo de c\u00e1ncer\u201d. <b><br \/> \u201cEl reto es entender los cambios epigen\u00e9ticos implicados en el c\u00e1ncer y utilizar esta informaci\u00f3n ya sea para la investigaci\u00f3n de nuevos tratamientos, o m\u00e1s importante a\u00fan, para hacer un diagn\u00f3stico precoz del c\u00e1ncer. En un futuro debemos ser capaces de detectar la alteraci\u00f3n epigen\u00e9tica antes de que se desarrolle el c\u00e1ncer\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El investigador Marcus Buschbeck del Instituto de Medicina Predictiva y Personalizada del C\u00e1ncer (IMPPC) de Badalona ha explicado sus \u00faltimos avnces en la investigaci\u00f3n de una prote\u00edna relacionada con el empaquetamiento del ADN y su implicaci\u00f3n en la diferenciaci\u00f3n celular el 21 de octubre dentro el ciclo de seminarios IDIBELL. El objetivo del grupo de [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-08 13:36:36","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11375"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11375"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11375\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11375"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11375"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11375"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}