{"id":11374,"date":"2011-11-03T00:00:00","date_gmt":"2011-11-02T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2011\/11\/03\/pedro-m-fernandez-salguero-los-transposones-podrian-representar-hasta-un-15-del-genoma-humano\/"},"modified":"2020-05-26T09:28:50","modified_gmt":"2020-05-26T07:28:50","slug":"pedro-m-fernandez-salguero-los-transposones-podrian-representar-hasta-un-15-del-genoma-humano","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2011\/11\/pedro-m-fernandez-salguero-los-transposones-podrian-representar-hasta-un-15-del-genoma-humano\/","title":{"rendered":"Pedro M. Fern\u00e1ndez Salguero: \u201cLos transposones podr\u00edan representar hasta un 15% del genoma humano\u201d"},"content":{"rendered":"<p>El investigador de la <a href=\"http:\/\/www.unex.es\/investigacion\/grupos\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Universidad de Extremadura<\/span><\/a> Pedro M. Fern\u00e1ndez Salguero ha explicado sus \u00faltimos avances en la investigaci\u00f3n de la funci\u00f3n de los transposones, secuencias cortas de ADN que se mueven por todo el genoma, en la regulaci\u00f3n de genes. Ha sido el 28 de octubre en el ciclo de seminarios del IDIBELL. <b><br \/> Fern\u00e1ndez Salguero ha destacado la necesidad de estudiar este material gen\u00e9tico que, \u201chasta hace pocos a\u00f1os, se consideraba ADN basura. Sin embargo, diversos estudios demuestran que est\u00e1n implicados en la regulaci\u00f3n de determinados genes\u201d. \u201cEs importante recalcar\u201d ha dicho el investigador \u201clos trasnposones podr\u00e1n representar el 15% del genoma humano y, de hecho,<b><br \/> todo el material gen\u00e9tico m\u00f3vil podr\u00eda representar entre el 40 y el 50%\u201d. <b><br \/> El laboratorio liderado por el investigador extreme\u00f1o se centra por un lado<b><br \/> en estudiar si los genes regulados por estos elementos tienen un papel en el desarrollo de c\u00e9lulas germinales, es decir c\u00f3mo podr\u00eda afectar a la fertilidad, y por el otro en el papel que podr\u00edan tener en c\u00e1ncer, especialmente en la migraci\u00f3n, invasi\u00f3n y met\u00e1stasis de las c\u00e9lulas tumorales. <b><br \/> \u201cSi se demuestra que estos elementos son importantes en la regulaci\u00f3n de los genes que mantienen la desdiferenciaci\u00f3n de las c\u00e9lulas tumorales, el paso previo a la met\u00e1stasis, podr\u00edamos estudiar la manera de modular estos trasnposones como herramienta terap\u00e9utica\u201d. Sin embargo Fern\u00e1ndez Salguero ha advertido que \u201ctodav\u00eda estamos muy lejos de esta posible aplicaci\u00f3n. De hecho, en humanos, todav\u00eda no conocemos casi nada de c\u00f3mo funcionan los trasnpososnes\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El investigador de la Universidad de Extremadura Pedro M. Fern\u00e1ndez Salguero ha explicado sus \u00faltimos avances en la investigaci\u00f3n de la funci\u00f3n de los transposones, secuencias cortas de ADN que se mueven por todo el genoma, en la regulaci\u00f3n de genes. Ha sido el 28 de octubre en el ciclo de seminarios del IDIBELL. Fern\u00e1ndez [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-11 19:19:00","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11374"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11374"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11374\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11374"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11374"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11374"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}