El gastroenter\u00f3logo del Hospital Universitario de Rangueil, en Touluse, e investigador del INSERM, Louis Buscail ha explicado sus \u00faltimos avances en terapia g\u00e9nica contra el c\u00e1ncer de p\u00e1ncreas avanzado en el ciclo de seminarios IDIBELL el pasado 11 de noviembre.
Actualmente, el \u00fanico tratamiento eficiente contra el c\u00e1ncer de p\u00e1ncreas es la cirug\u00eda. El agente quimioterap\u00e9utico gemcitabina mejora el estado del paciente pero su supervivencia no se alarga. El equipo de Louis Buscail ha dise\u00f1ado una nueva terapia g\u00e9nica mediante \u201cun compuesto gen\u00e9tico que sensibiliza las c\u00e9lulas tumorales a la gemcitabina haciendo que \u00e9sta resulte mucho m\u00e1s eficiente ya qu\u00e9 induce la muerte celular por apoptossi y la regresi\u00f3n tumoral\u201d.
Tras probar esta terapia en animales, el a\u00f1o 2010 Buscail puso en marcha un ensayo cl\u00ednico fase I con 12 pacientes. A la espera de los resultados, el investigador franc\u00e9s se muestra prudente y asegura que \u201chay que ir paso a paso. Nuestro siguiente reto es llegar a la fase II para poder probar la terapia con muchos m\u00e1s pacientes\u201d.
Paralelamente, el equipo de Buscail contin\u00faa con la investigaci\u00f3n a la b\u00fasqueda de biomarcadores que puedan ser \u00fatiles para nuevos tratamientos de c\u00e1ncer de p\u00e1ncreas o para mejorar su diagnosis.<\/p>\n","protected":false},"excerpt":{"rendered":"
El gastroenter\u00f3logo del Hospital Universitario de Rangueil, en Touluse, e investigador del INSERM, Louis Buscail ha explicado sus \u00faltimos avances en terapia g\u00e9nica contra el c\u00e1ncer de p\u00e1ncreas avanzado en el ciclo de seminarios IDIBELL el pasado 11 de noviembre. Actualmente, el \u00fanico tratamiento eficiente contra el c\u00e1ncer de p\u00e1ncreas es la cirug\u00eda. El agente […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"publishpress_future_action":{"enabled":false,"date":"2024-05-10 13:12:42","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11368"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11368"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11368\/revisions"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11368"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11368"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11368"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}