{"id":11358,"date":"2012-02-14T00:00:00","date_gmt":"2012-02-13T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2012\/02\/14\/montserrat-baiget-la-medicina-o-sera-genomica-o-no-sera\/"},"modified":"2023-03-02T16:08:58","modified_gmt":"2023-03-02T15:08:58","slug":"montserrat-baiget-la-medicina-o-sera-genomica-o-no-sera","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2012\/02\/montserrat-baiget-la-medicina-o-sera-genomica-o-no-sera\/","title":{"rendered":"Montserrat Baiget: \u201cLa medicina, o ser\u00e1 gen\u00f3mica o no ser\u00e1\u201d"},"content":{"rendered":"<p>La directora del servicio de gen\u00e9tica del <a href=\"http:\/\/www.santpau.es\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Hospital de Sant Pau<\/span><\/a>, Montserrat Baiget, ha explicado los \u00faltimos avances de su grupo en la investigaci\u00f3n de la farmacogen\u00e9tica. Ha sido el 10 de febrero en el marco del ciclo de seminarios IDIBELL.<\/p>\n<p>Partiendo de la premisa que el futuro de la medicina y las nuevas terapias pasan por aplicar la gen\u00f3mica, el grupo que dirige Montserrat Baiget se centra en la farmacogen\u00e9tica. \u201cLas diferencias en la secuencia del ADN o del ARN en genes relacionados con la respuesta de los pacientes a los f\u00e1rmacos deben permitirnos estratificar a los pacientes en subpoblaciones seg\u00fan respondan de manera m\u00e1s o menos efectiva, o con mayor o menor toxicidad a determinados f\u00e1rmacos\u201d de forma que \u201cno damos f\u00e1rmacos a pacientes que puedan tener efectos secundarios adversos y que adem\u00e1s no son efectivos para ellos\u201d.<\/p>\n<p>Baiget ha explicado su investigaci\u00f3n con el CPT11\/Irinotecan, un f\u00e1rmaco utilizado contra el c\u00e1ncer de colon que inhibe una enzima concreta (la topoisomerasa I), y puede provocar efectos secundarios graves. \u201cHemos realizado un ensayo en qu\u00e9 determinamos que a los individuos que presentan un genotipo favorable al f\u00e1rmaco se les podr\u00eda administrar m\u00e1s del doble de la dosis recomendada actualmente sin que sufrieran efectos secundarios y aumentando la eficacia del f\u00e1rmaco. Mientras que los genotipos desfavorables presentan efectos secundarios graves muy por debajo de esta dosis recomendada\u201d.<\/p>\n<p>Durante el a\u00f1o 2012 iniciar\u00e1n un nuevo ensayo cl\u00ednico para determinar en qu\u00e9 dosis el Irinotecan puede ser m\u00e1s eficaz para los genotipos favorables.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>La directora del servicio de gen\u00e9tica del Hospital de Sant Pau, Montserrat Baiget, ha explicado los \u00faltimos avances de su grupo en la investigaci\u00f3n de la farmacogen\u00e9tica. Ha sido el 10 de febrero en el marco del ciclo de seminarios IDIBELL. Partiendo de la premisa que el futuro de la medicina y las nuevas terapias [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":22229,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[1],"tags":[],"class_list":["post-11358","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2024-11-29 17:25:34","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11358"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11358\/revisions"}],"predecessor-version":[{"id":22230,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11358\/revisions\/22230"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/22229"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}