{"id":11333,"date":"2012-04-03T00:00:00","date_gmt":"2012-04-02T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2012\/04\/03\/investigadores-del-idibell-crean-una-aplicacion-informatica-que-permite-el-analisis-estadistico-en-linea-de-datos-de-expresion-de-genes\/"},"modified":"2022-09-09T16:45:50","modified_gmt":"2022-09-09T14:45:50","slug":"investigadores-del-idibell-crean-una-aplicacion-informatica-que-permite-el-analisis-estadistico-en-linea-de-datos-de-expresion-de-genes","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2012\/04\/investigadores-del-idibell-crean-una-aplicacion-informatica-que-permite-el-analisis-estadistico-en-linea-de-datos-de-expresion-de-genes\/","title":{"rendered":"Investigadores del IDIBELL crean una aplicaci\u00f3n inform\u00e1tica que permite el an\u00e1lisis estad\u00edstico en l\u00ednea de datos de expresi\u00f3n de genes"},"content":{"rendered":"<p>La revista <a href=\"http:\/\/www.elsevier.com\/wps\/find\/journaldescription.cws_home\/351\/description\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">Computers in Biology and Medicine<\/span><\/a> ha publicado un art\u00edculo sobre la nueva aplicaci\u00f3n inform\u00e1tica BootstRatio, creada por investigadores del IDIBELL, que permite el an\u00e1lisis estad\u00edstico en l\u00ednea de datos de expresi\u00f3n de genes. La aplicaci\u00f3n es accesible a trav\u00e9s de <a class=\"enllac\" href=\"http:\/\/regstattools.net\/br\">http:\/\/regstattools.net\/br<\/a> y ya la est\u00e1n utilizando cient\u00edficos de todo el mundo.<\/p>\n<p>Los investigadores del grupo de investigaci\u00f3n de Gen\u00e9tica Molecular Humana del IDIBELL, liderado por Virginia Nunes, se encontraban con un problema para dotar de significaci\u00f3n los resultados de los an\u00e1lisis estad\u00edsticos de los datos de expresi\u00f3n de genes. La mayor\u00eda de los c\u00e1lculos estad\u00edsticos que se hacen para comparar datos de expresi\u00f3n de genes presuponen una distribuci\u00f3n normal de estos datos y esta distribuci\u00f3n no siempre es real.<\/p>\n<p>A partir de este problema y junto con Ramon Cl\u00e8ries, experto en estad\u00edstica del grupo de Prevenci\u00f3n y Control del C\u00e1ncer del IDIBELL, decidieron trabajar en un an\u00e1lisis estad\u00edstico que, utilizando t\u00e9cnicas de remuestreo permitiera generar una distribuci\u00f3n hipot\u00e9tica de los datos sin partir de ninguna distribuci\u00f3n inicial, y que expusiera los datos en un lenguaje comprensible para el cient\u00edfico.<\/p>\n<p>As\u00ed es como nace la aplicaci\u00f3n BootstRatio a la cual se puede acceder desde un servidor remoto. \u201cSe introducen los datos y en pocos tiempo el programa env\u00eda los resultados por correo electr\u00f3nico en un lenguaje comprensible para el cient\u00edfico\u201d, ha explicado Miguel L\u00f3pez de Heredia, investigador <a href=\"http:\/\/www.ciberer.es\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\">CIBERER <\/span><\/a>del grupo de investigaci\u00f3n de Gen\u00e9tica Molecular Humana del IDIBELL. \u201cLos estad\u00edsticos y los bi\u00f3logos a veces hablamos lenguajes diferentes. Esta nueva herramienta permite una interpretaci\u00f3n biol\u00f3gica de los resultados del an\u00e1lisis estad\u00edstico\u201d.<\/p>\n<p>Cl\u00e8ries ha explicado que la aplicaci\u00f3n BootstRatio \u201ces muy f\u00e1cil de usar y no requiere especializaci\u00f3n estad\u00edstica\u201d.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Referencia del art\u00edculo<\/strong><\/p>\n<p>Cl\u00e8ries R., Galvez J., Espino M., Ribes J., Nunes V. and L\u00f3pez de Heredia M. BootsRatio: A web-based stsatistical analysis of fold-change in qPCR and RT-qPCR data using resampling methods. Computers in Biology and Medicine 42 (2012) 438-445. doi: 10.1016\/j.compbiomed.2011.12-012<b><b><b><b><strong><b><br \/>\n<\/b><\/strong><\/b><\/b><\/b><\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La revista Computers in Biology and Medicine ha publicado un art\u00edculo sobre la nueva aplicaci\u00f3n inform\u00e1tica BootstRatio, creada por investigadores del IDIBELL, que permite el an\u00e1lisis estad\u00edstico en l\u00ednea de datos de expresi\u00f3n de genes. La aplicaci\u00f3n es accesible a trav\u00e9s de http:\/\/regstattools.net\/br y ya la est\u00e1n utilizando cient\u00edficos de todo el mundo. Los investigadores [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":21376,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[184,186,222,305,293,297],"tags":[],"class_list":["post-11333","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-area-cancer","category-area-medicina-traslacional","category-control-y-prevencion-del-cancer","category-genetica-molecular-humana-programa-de-genes-enfermedad-y-terapia","category-programa-de-epidemiologia-salud-publica-prevencion-del-cancer-y-curas-paliativas","category-programa-de-genes-enfermedad-y-terapia"],"publishpress_future_action":{"enabled":false,"date":"2025-06-14 07:10:27","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11333"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11333\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/21376"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11333"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11333"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}