{"id":11329,"date":"2012-04-13T00:00:00","date_gmt":"2012-04-12T22:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2012\/04\/13\/oriol-casanovas-opina-sobre-las-limitaciones-de-las-terapias-antiangiogenicas-en-nature\/"},"modified":"2022-09-09T16:21:13","modified_gmt":"2022-09-09T14:21:13","slug":"oriol-casanovas-opina-sobre-las-limitaciones-de-las-terapias-antiangiogenicas-en-nature","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2012\/04\/oriol-casanovas-opina-sobre-las-limitaciones-de-las-terapias-antiangiogenicas-en-nature\/","title":{"rendered":"Oriol Casanovas opina sobre las limitaciones de las terapias antiangiog\u00e9nicas en Nature"},"content":{"rendered":"<p>El investigador del IDIBELL Oriol Casanovas publica en el \u00faltimo n\u00famero de la revista <a href=\"http:\/\/www.nature.com\/nature\/journal\/v484\/n7392\/index.html\" target=\"_blank\" rel=\"noopener noreferrer\"><span class=\"enllac\"><span class=\"enllac\">Nature<\/span><\/span><\/a> un art\u00edculo que bajo el t\u00edtulo \u201cLimitations ofoff therapies exposed\u201d destaca la necesidad de conocer las limitaciones de la terapias antiangiog\u00e9nicas para abrir puertas a nuevas combinaciones o aproximaciones terap\u00e9uticas que impliquen mayores beneficios para los pacientes.<\/p>\n<p>En concreto, Casanovas comenta dos publicaciones recientes d\u00f3nde se exponen las limitaciones cl\u00ednicas de determinados tratamientos. De una parte, la combinaci\u00f3n de antiangiog\u00e9nicos y quimioterapia, un tratamiento muy utilizado pero que tiene como limitaci\u00f3n que el f\u00e1rmaco antiangiog\u00e9nico al frenar el crecimiento de los vasos sangu\u00edneos del tumor tambi\u00e9n evita que llegue la quimioterapia. Y por la otra, el uso de un f\u00e1rmaco antiangiog\u00e9nico que reduce los tumores de mama pero no acaba con las c\u00e9lulas madres tumorales que adem\u00e1s aumentan en n\u00famero, haciendo que el tumor que queda sea m\u00e1s agresivo y de peor pron\u00f3stico.<\/p>\n<p>Para Casanovas \u201cest\u00e1 claro que los tratamientos antiangiog\u00e9nicos son efectivos pero debemos entender las limitaciones que tienen por qu\u00e9 s\u00f3lo as\u00ed podremos buscar nuevas combinaciones, secuenciarlas de forma diferente\u2026 u otras innovaciones que puedan suponer un mayor beneficio para el paciente\u201d.<\/p>\n<p>&nbsp;<\/p>\n<p><b><b><b><b><strong>Referencia del art\u00edculo<\/strong><b><br \/>\n<\/b><\/b><\/b><\/b><\/b><\/p>\n<p>Oriol Casanovas. Limitations of Therapies exposed. Nature. Vol 484 (44-46). 5 April 2012<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El investigador del IDIBELL Oriol Casanovas publica en el \u00faltimo n\u00famero de la revista Nature un art\u00edculo que bajo el t\u00edtulo \u201cLimitations ofoff therapies exposed\u201d destaca la necesidad de conocer las limitaciones de la terapias antiangiog\u00e9nicas para abrir puertas a nuevas combinaciones o aproximaciones terap\u00e9uticas que impliquen mayores beneficios para los pacientes. En concreto, Casanovas [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":21364,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[242,184,371,281],"tags":[],"class_list":["post-11329","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-angiogenesis-tumoral","category-area-cancer","category-procure","category-programa-de-mecanismos-moleculares-y-terapia-experimental-en-oncologia-oncobell"],"publishpress_future_action":{"enabled":false,"date":"2024-12-30 09:48:48","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11329"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11329\/revisions"}],"predecessor-version":[{"id":21365,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11329\/revisions\/21365"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/21364"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11329"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11329"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}