{"id":11213,"date":"2013-01-25T00:00:00","date_gmt":"2013-01-24T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2013\/01\/25\/antoni-bayes-genis-el-proximo-parche-cardiaco-inteligente-sera-una-biomembrana-y-un-tejido-cardiaco\/"},"modified":"2022-03-02T16:12:09","modified_gmt":"2022-03-02T15:12:09","slug":"antoni-bayes-genis-el-proximo-parche-cardiaco-inteligente-sera-una-biomembrana-y-un-tejido-cardiaco","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2013\/01\/antoni-bayes-genis-el-proximo-parche-cardiaco-inteligente-sera-una-biomembrana-y-un-tejido-cardiaco\/","title":{"rendered":"Antoni Bay\u00e9s-Gen\u00eds: \u00bbEl pr\u00f3ximo parche card\u00edaco inteligente ser\u00e1 una biomembrana y un tejido card\u00edaco\u00bb"},"content":{"rendered":"
La terapia celular cada vez tendr\u00e1 m\u00e1s peso en la investigaci\u00f3n card\u00edaca, dijo Antoni Bay\u00e9s-Gen\u00eds en el Seminario IDIBELL \u00abBioprosthesis for cardiac repair\u00bb, que tuvo lugar en la Sala Pau Viladiu en el Hospital Duran i Reynals-ICO, el pasado 18 de enero. Bay\u00e9s-Gen\u00eds es jefe de servicio Cardiolog\u00eda del Hospital Universitario Germans Trias i Pujol de Badalona e investigador del Instituto de Investigaci\u00f3n en Ciencias de la Salud Germans Trias i Pujol (IGTP).<\/p>\n
El investigador habl\u00f3 sobre la historia del infarto de miocardio en los \u00faltimos 100 a\u00f1os. Luego se centr\u00f3 en la capacidad regenerativa del coraz\u00f3n humano en los \u00faltimos 10 a\u00f1os. La terapia celular es la primera opci\u00f3n para tratar a los pacientes tras un infarto de miocardio. \u201cEl tratamiento con m\u00e9dula \u00f3sea tuvo un gran impacto en los pacientes de infarto agudo de miocardio\u201d, explica el investigador.<\/p>\n
La ingenier\u00eda de tejidos card\u00edacos<\/strong><\/p>\n \u00bfQu\u00e9 pasos hay que seguir hasta la aplicaci\u00f3n cl\u00ednica? Es necesaria la ingenier\u00eda de tejidos para el m\u00fasculo del coraz\u00f3n. Los injertos de ingenier\u00eda tisular se adaptan bien y mantienen la estructura del tejido de miocardio.<\/p>\n \u00abRob Langer, del MIT, est\u00e1 trabajando en Nanowired 3-D, unos parches card\u00edacos para regenerar el tejido de miocardio. Otro enfoque diferente es la aproximaci\u00f3n de Doris Taylor sobre ingenier\u00eda de tejidos para el m\u00fasculo del coraz\u00f3n, con tratamiento enzim\u00e1tico, tanto f\u00edsico como qu\u00edmico, la vascularizaci\u00f3n y recelularizaci\u00f3n aut\u00f3loga de tejidos. Adem\u00e1s, utilizando el mismo concepto, el grupo de Karen Christman usan un coraz\u00f3n para extraer todas sus c\u00e9lulas y construir otro nuevo\u00bb, dijo Bay\u00e9s-Gen\u00eds.<\/p>\n \u00abMi grupo obtiene tejido adiposo cardiaco derivado de las c\u00e9lulas progenitoras\u00bb, explic\u00f3 el investigador y continu\u00f3: \u00abQueremos obtener m\u00e1s c\u00e9lulas vasculares del tejido graso que rodea el coraz\u00f3n. Provocamos, en un modelo animal, un infarto para analizar el tama\u00f1o de la cicatriz\u00bb. El investigador explica que para llevar a cabo sus ensayos cl\u00ednicos necesitaban candidatos CABG con cicatriz cr\u00f3nica no revascularizable. \u00abUtilizamos implantes avanzados y materiales bioactivos para los \u00f3rganos cr\u00edticos desarrollados por la Universidad Polit\u00e9cnica de Valencia (UPV), entre otras entidades, y otras tecnolog\u00edas para el desarrollo de la Universitat Polit\u00e8cnica de Catalunya (UPC), sobre electro-estimulaci\u00f3n mec\u00e1nica\u00bb, explic\u00f3 el investigador cardiovascular.<\/p>\n La pr\u00f3xima generaci\u00f3n de materiales que se est\u00e1n desarrollando ser\u00e1 un parche inteligente: una bio-membrana y un tejido card\u00edaco. Los microelectrodos se implantan en el coraz\u00f3n en un modelo porcino, cuyo coraz\u00f3n y sistema vascular es el m\u00e1s pr\u00f3ximo al humano, y que \u00abpermite medir y monitorear la regeneraci\u00f3n in vivo\u00bb, dijo Bay\u00e9s-Gen\u00eds.<\/p>\n \u00abQuedan a\u00fan muchas cosas que hacer y aprender en la regeneraci\u00f3n de tejidos card\u00edacos. Mi grupo de investigaci\u00f3n quiere traducir los resultados de la investigaci\u00f3n a la pr\u00e1ctica cl\u00ednica \u00ab, concluye el investigador.<\/p>\n","protected":false},"excerpt":{"rendered":" La terapia celular cada vez tendr\u00e1 m\u00e1s peso en la investigaci\u00f3n card\u00edaca, dijo Antoni Bay\u00e9s-Gen\u00eds en el Seminario IDIBELL \u00abBioprosthesis for cardiac repair\u00bb, que tuvo lugar en la Sala Pau Viladiu en el Hospital Duran i Reynals-ICO, el pasado 18 de enero. Bay\u00e9s-Gen\u00eds es jefe de servicio Cardiolog\u00eda del Hospital Universitario Germans Trias i Pujol […]<\/p>\n","protected":false},"author":6,"featured_media":19993,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[373,374],"tags":[],"class_list":["post-11213","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divulgacion-y-educacion","category-innovacion"],"publishpress_future_action":{"enabled":false,"date":"2024-09-15 01:40:27","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11213"}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11213"}],"version-history":[{"count":3,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11213\/revisions"}],"predecessor-version":[{"id":19994,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11213\/revisions\/19994"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/19993"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11213"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11213"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}