El jefe de la Unidad de Gen\u00e9tica Molecular del Hospital Universitario de Valdecilla, Santander, Jos\u00e9 Luis Fern\u00e1ndez-Luna ha explicado el 1 de marzo sus \u00faltimos avances en la investigaci\u00f3n de c\u00e9lulas madre tumorales de glioblastoma, el tumor cerebral m\u00e1s agresivo, en una conferencia en el marco del ciclo de seminarios IDIBELL.<\/p>\n
Las t\u00e9cnicas de neurocirug\u00eda han mejorado mucho en los \u00faltimos a\u00f1os. A\u00fan as\u00ed, actualmente es imposible evitar las reca\u00eddas del glioblastoma ya que seg\u00fan ha explicado Jos\u00e9 Luis Fern\u00e1ndez-Luna, existe una zona peritumoral infectada con c\u00e9lulas madre tumorales que no se puede extirpar porque es tejido normal del cerebro. Esa poblaci\u00f3n de c\u00e9lulas madre tumorales tiene una gran capacidad para migrar dentro del cerebro\u201d.<\/p>\n
Fern\u00e1ndez-Luna ha explicado c\u00f3mo han logrado identificar estas c\u00e9lulas madre tumorales y su trabajo actual, que se basa ahora en seguir investigando los mecanismos de invasi\u00f3n e identificar nuevas dianas terap\u00e9uticas que puedan bloquearlos.<\/p>\n
\u201cActualmente, estamos probando en ratones un inhibidor de la ruta NFKb que lleva a estas c\u00e9lulas madre a la senescencia y, en colaboraci\u00f3n con una plataforma bioinform\u00e1tica, estamos buscando entre m\u00e1s de cinco millones de compuestos, nuevos candidatos a actuar sobre diversas dianas terap\u00e9uticas\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
El jefe de la Unidad de Gen\u00e9tica Molecular del Hospital Universitario de Valdecilla, Santander, Jos\u00e9 Luis Fern\u00e1ndez-Luna ha explicado el 1 de marzo sus \u00faltimos avances en la investigaci\u00f3n de c\u00e9lulas madre tumorales de glioblastoma, el tumor cerebral m\u00e1s agresivo, en una conferencia en el marco del ciclo de seminarios IDIBELL. Las t\u00e9cnicas de neurocirug\u00eda […]<\/p>\n","protected":false},"author":6,"featured_media":19787,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[373,374],"tags":[],"class_list":["post-11192","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divulgacion-y-educacion","category-innovacion"],"publishpress_future_action":{"enabled":false,"date":"2025-05-03 03:33:38","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11192","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11192"}],"version-history":[{"count":0,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11192\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/19787"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11192"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11192"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}