{"id":11185,"date":"2013-03-20T00:00:00","date_gmt":"2013-03-19T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2013\/03\/20\/angel-carracedosolo-50-de-los-farmacos-de-primera-linea-son-eficaces\/"},"modified":"2022-02-18T15:22:10","modified_gmt":"2022-02-18T14:22:10","slug":"angel-carracedosolo-50-de-los-farmacos-de-primera-linea-son-eficaces","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2013\/03\/angel-carracedosolo-50-de-los-farmacos-de-primera-linea-son-eficaces\/","title":{"rendered":"\u00c1ngel Carracedo:\u201cS\u00f3lo el 50% de los f\u00e1rmacos de primera l\u00ednea son eficaces\u201d"},"content":{"rendered":"
El catedr\u00e1tico de Medicina Legal y director del grupo de medicina gen\u00f3mica de la Universidad de Santiago de Compostela, \u00c1ngel Carracedo habl\u00f3 de los retos de futuro de la farmacog\u00e9netica en el \u00e1mbito de la cl\u00ednica. Fue el pasado 15 de marzo en una conferencia dentro el marco de los seminarios IDIBELL.<\/p>\n
Actualmente s\u00f3lo un 50% de los f\u00e1rmacos de primera l\u00ednea son efectivos y los efectos adversos de los f\u00e1rmacos son la cuarta causa de muerte a los Estados Unidos y la octava en Europa. Seg\u00fan \u00c1ngel Carracedo \u201cdos individuos no responden igual a un f\u00e1rmaco ni en condiciones de salud ni, mucho menos, en condiciones de enfermedad. Uno de los factores que determinan esta respuesta es la gen\u00e9tica\u201d.<\/p>\n
Conocer la gen\u00e9tica del paciente podr\u00eda permitir administrarle s\u00f3lo los medicamentos adecuados y ahorrarle los efectos adversos de aquellos f\u00e1rmacos que no le serian eficaces. De hecho, seg\u00fan ha explicado Carracedo, la FDA y la EMEA (las agencias reguladoras de los medicamentos en Estados Unidos y Europa respectivamente) ya han hecho varias recomendaciones en la ficha t\u00e9cnica de diversos f\u00e1rmacos, especialmente de quimioterapia, de forma que sea obligatorio el an\u00e1lisis gen\u00e9tico antes de su prescripci\u00f3n. Sin embargo Carracedo ha advertido que \u201cno a todos los cl\u00ednicos les llega esta informaci\u00f3n y que no siempre se utiliza de manera adecuada\u201d.<\/p>\n
\u201cDebemos seguir trabajando\u201d ha dicho Carracedo \u201cen la validaci\u00f3n de nuevos biomarcadores que tengan una relaci\u00f3n coste\/eficacia asumible y encontrar la manera de implementar la farmacogen\u00e9tica de la manera m\u00e1s eficiente en la pr\u00e1ctica cl\u00ednica\u201d.<\/p>\n","protected":false},"excerpt":{"rendered":"
El catedr\u00e1tico de Medicina Legal y director del grupo de medicina gen\u00f3mica de la Universidad de Santiago de Compostela, \u00c1ngel Carracedo habl\u00f3 de los retos de futuro de la farmacog\u00e9netica en el \u00e1mbito de la cl\u00ednica. Fue el pasado 15 de marzo en una conferencia dentro el marco de los seminarios IDIBELL. Actualmente s\u00f3lo un […]<\/p>\n","protected":false},"author":6,"featured_media":19759,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[373,374],"tags":[],"class_list":["post-11185","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divulgacion-y-educacion","category-innovacion"],"publishpress_future_action":{"enabled":false,"date":"2025-01-29 04:22:23","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11185","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11185"}],"version-history":[{"count":3,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11185\/revisions"}],"predecessor-version":[{"id":19761,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11185\/revisions\/19761"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/19759"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11185"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11185"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}