El catedr\u00e1tico de microbiolog\u00eda e investigador del grupo de Gen\u00e9tica de microbacterias de la Universidad de Zaragoza, Carlos Mart\u00edn, ha explicado en qu\u00e9 fase se encuentran los primeros ensayos de la MTBVAC. La conferencia celebrada el 7 de junio se enmarca en el ciclo de seminarios IDIBELL. Mart\u00edn ha explicado el proceso de creaci\u00f3n de la vacuna, la primera con bacilo atenuado de tuberculosis y c\u00f3mo al principio result\u00f3 dif\u00edcil porque \u201cnadie cre\u00eda que una cepa atenuada pudiera llegar a la cl\u00ednica\u201d. El investigador explica que se tuvieron que cumplir los requisitos pactados en Ginebra para el uso de vacunas vivas, es decir las cepas deben presentar dos modificaciones gen\u00e9ticas para que no pueda recuperar la virulencia.<\/p>\n
La MTBVAC es una vacuna que busca activar el sistema inmunitario para que sea capaz de reconocer al agente infeccioso y proteja a largo plazo frente a la forma m\u00e1s com\u00fan de la enfermedad: la respiratoria. La actual vacuna BCG protege contra diferentes formas de tuberculosis en ni\u00f1os, pero su protecci\u00f3n en tuberculosis pulmonar de adultos es muy variable.<\/p>\n
La idea de Carlos Mart\u00edn es que esta nueva vacuna pueda sustituir a BCG. \u201cNecesitamos que tenga una respuesta mejor que BCG, y el list\u00f3n est\u00e1 muy alto\u201d. Actualmente, la vacuna de Mart\u00edn est\u00e1 en fase I de ensayo cl\u00ednico para comprobar la seguridad y la inmunogenicidad en el el Complejo Hospitalario de la Universidad de Vaudois (Lausana, Suiza).<\/p>\n","protected":false},"excerpt":{"rendered":"
El catedr\u00e1tico de microbiolog\u00eda e investigador del grupo de Gen\u00e9tica de microbacterias de la Universidad de Zaragoza, Carlos Mart\u00edn, ha explicado en qu\u00e9 fase se encuentran los primeros ensayos de la MTBVAC. La conferencia celebrada el 7 de junio se enmarca en el ciclo de seminarios IDIBELL. Mart\u00edn ha explicado el proceso de creaci\u00f3n de […]<\/p>\n","protected":false},"author":6,"featured_media":19127,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[373,374,1],"tags":[],"class_list":["post-11142","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divulgacion-y-educacion","category-innovacion","category-sin-categorizar"],"publishpress_future_action":{"enabled":false,"date":"2025-03-21 01:30:33","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/comments?post=11142"}],"version-history":[{"count":2,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11142\/revisions"}],"predecessor-version":[{"id":19128,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/posts\/11142\/revisions\/19128"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media\/19127"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/media?parent=11142"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/categories?post=11142"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/es\/wp-json\/wp\/v2\/tags?post=11142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}