{"id":10290,"date":"2018-12-13T00:00:00","date_gmt":"2018-12-12T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/es\/blog\/2018\/12\/13\/el-idibell-y-el-hospital-de-bellvitge-desarrollan-un-tratamiento-para-ganar-la-batalla-a-las-infecciones-hospitalarias\/"},"modified":"2020-08-07T10:47:19","modified_gmt":"2020-08-07T08:47:19","slug":"el-idibell-y-el-hospital-de-bellvitge-desarrollan-un-tratamiento-para-ganar-la-batalla-a-las-infecciones-hospitalarias","status":"publish","type":"post","link":"https:\/\/idibell.cat\/es\/2018\/12\/el-idibell-y-el-hospital-de-bellvitge-desarrollan-un-tratamiento-para-ganar-la-batalla-a-las-infecciones-hospitalarias\/","title":{"rendered":"El IDIBELL y el Hospital de Bellvitge desarrollan un tratamiento para ganar la batalla a las infecciones hospitalarias"},"content":{"rendered":"<p>La resistencia de las bacterias a los antibi\u00f3ticos es uno de los problemas m\u00e1s importantes a los que se enfrenta la salud p\u00fablica a nivel mundial. El continuo crecimiento de las infecciones causadas por estos microbios puede causar m\u00e1s de 10 millones de muertes anuales en el a\u00f1o 2050, como suced\u00eda en la era preantibi\u00f3tica.<\/p>\n<p>La mayor\u00eda de estas infecciones se adquieren dentro de los hospitales, por lo que, adem\u00e1s, grandes \u00e9xitos de la medicina como los trasplantes o la inmunoterapia contra el c\u00e1ncer pueden peligrar por ellas. El problema es especialmente urgente en las UCI. El 70% de los pacientes ingresados m\u00e1s de 7 d\u00edas desarrollan una infecci\u00f3n y reciben tratamientos antibi\u00f3ticos, con unos costes de miles de millones para los sistemas de salud a nivel mundial.<\/p>\n<p>Investigadores del Hospital Universitario de Bellvitge y del Instituto de Investigaci\u00f3n Biom\u00e9dica de Bellvitge (IDIBELL) han desarrollado unos glicopol\u00edmeros que permiten eliminar anticuerpos que se unen a las bacterias Gram-negativas sin causarles ning\u00fan da\u00f1o. Estos anticuerpos (llamados bloqueantes) son utilizados por las bacterias como escudo.<\/p>\n<p>Si se eliminan los anticuerpos bloqueantes, se elimina el escudo y los anticuerpos con capacidad de matar a las bacterias pueden actuar de forma inmediata. Ello representa una gran ventaja de los glicopol\u00edmeros comparado con otras terapias como las vacunas, que necesitan varias semanas para poder generar una inmunidad protectora.<\/p>\n<p>El nuevo tratamiento, que puede tener un importante impacto sanitario y econ\u00f3mico para los sistemas de salud, ha sido patentado internacionalmente. A comienzos de 2018 se cre\u00f3 la empresa spin-off del IDIBELL RemAb Therapeutics (<a href=\"https:\/\/remabtx.com;\">https:\/\/remabtx.com;<\/a> @RemAb_Tx), que est\u00e1 actualmente ejecutando los procedimientos precl\u00ednicos con las\u00a0autoridades regulatorias y una ronda de inversi\u00f3n, con el objetivo de iniciar los pri-meros ensayos cl\u00ednicos de los glicoconjugados en humanos a principios del a\u00f1o 2020.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>El nuevo tratamiento evitar\u00eda que m\u00e1s de 4 millones de pacientes ingresados en las Unidades de Cuidados Intensivos (UCI) a nivel mundial desarrollen infecciones y necesiten antibi\u00f3ticos<\/p>\n","protected":false},"author":6,"featured_media":10291,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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