{"id":6474,"date":"2013-01-25T00:00:00","date_gmt":"2013-01-24T23:00:00","guid":{"rendered":"https:\/\/idibell.cat\/en\/blog\/2020\/05\/01\/antoni-bayes-genis-the-next-generation-of-smart-cardiac-patch-concept-is-a-bio-membrane-and-a-cardiac-tissue\/"},"modified":"2022-03-02T16:11:18","modified_gmt":"2022-03-02T15:11:18","slug":"antoni-bayes-genis-the-next-generation-of-smart-cardiac-patch-concept-is-a-bio-membrane-and-a-cardiac-tissue","status":"publish","type":"post","link":"https:\/\/idibell.cat\/en\/2013\/01\/antoni-bayes-genis-the-next-generation-of-smart-cardiac-patch-concept-is-a-bio-membrane-and-a-cardiac-tissue\/","title":{"rendered":"Antoni Bay\u00e8s-Gen\u00eds: \u201cThe next generation of smart cardiac patch concept is a bio-membrane and a cardiac tissue\u201d"},"content":{"rendered":"

Cell therapy is something that will increase in the heart research, told Antoni Bay\u00e8s-Gen\u00eds in the \u201cBioprosthesis for cardiac repair\u201d IDIBELL seminar that took place in Sala Pau Viladiu at the Hospital Duran i Reynals-ICO, last January 18th. Bay\u00e9s-Gen\u00eds <\/span>is Head of<\/span> the Cardiology<\/span> Service<\/span> at the University Hospital<\/span> Germans Trias i<\/span> Pujol in Badalona<\/span> and<\/span> researcher at the<\/span> Research Institute<\/span> for<\/span> Health Sciences<\/span> Germans Trias i Pujol<\/span> (IGTP)<\/span>.<\/span><\/p>\n

Bay\u00e8s-Gen\u00eds talked about the history of the myocardial infarction in the last 100 years. Then he focussed in the human heart regenerative capacity in the last 10 years. Cell therapy was the first option in order to treat patients after I.C. The treatment with bone-marrow had a great impact in patients in Acute M. I.<\/p>\n

Cardiac tissue engineering <\/strong> <\/p>\n

<\/strong> Which steps we need to follow until clinical application? We need tissue engineering for heart muscle. The engineered tissue grafts adapt well and maintain the structure of the myocardial tissue.<\/p>\n

\u201cRob Langer, from the MIT, is working in Nanowired 3-D cardiac patches to regenerate the myocardiac tissue. Another different approach is about Doris Taylor that is about tissue engineering for heart muscle, with enzyme, physic and chemical treatment, authology vascularization and recellularization of tissues. Also, using the same concept, the group of Karen Christman use the heart in order to extract heart cells to build another new one\u201d, said Bay\u00e8s-Gen\u00eds.<\/p>\n

\u201cMy group obtains cardiac adipose tissue derived of progenitor cells\u201d, explained the researcher and he continued, \u201cWe want to obtain more vascular cells from the fat tissue surrounding the heart. We provoke, in an animal model, an infarct to see the size of the scar\u201d. The researcher explains that to perform their clinical trials they needed a candidate CABG with chronic scar non-revascularizable.<\/p>\n

\u201cWe use advanced implants and bioactive materials for critical organs developed by UPV, among other entities, and other technology develop for the UPC, about electro-mechanical stimulation\u201d, explained the cardiovascular researcher.<\/p>\n

The next generation is a smart patch concept: a bio-membrane and a cardiac tissue. Microelectrodes are implanted in heart in pig model, which heart and vascular system is the most closest to the human one, and \u201cit allows measuring and monitoring the regeneration in vivo<\/em>\u201d, said Bay\u00e8s-Gen\u00eds.<\/p>\n

\u201cThere are many things to do, many things to learn in regeneration tissue heart. My research group wants to translate the results of the research to the clinical practice\u201d, concluded the researcher.<\/p>\n","protected":false},"excerpt":{"rendered":"

Cell therapy is something that will increase in the heart research, told Antoni Bay\u00e8s-Gen\u00eds in the \u201cBioprosthesis for cardiac repair\u201d IDIBELL seminar that took place in Sala Pau Viladiu at the Hospital Duran i Reynals-ICO, last January 18th. Bay\u00e9s-Gen\u00eds is Head of the Cardiology Service at the University Hospital Germans Trias i Pujol in Badalona […]<\/p>\n","protected":false},"author":6,"featured_media":19973,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[305,304],"tags":[],"class_list":["post-6474","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-innovation","category-outreach-and-education"],"publishpress_future_action":{"enabled":false,"date":"2024-12-25 11:50:32","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category"},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/posts\/6474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=6474"}],"version-history":[{"count":3,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/posts\/6474\/revisions"}],"predecessor-version":[{"id":19974,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/posts\/6474\/revisions\/19974"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media\/19973"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=6474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/categories?post=6474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/tags?post=6474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}