{"id":450,"date":"2019-05-08T15:57:41","date_gmt":"2019-05-08T13:57:41","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=450"},"modified":"2024-12-10T12:05:27","modified_gmt":"2024-12-10T11:05:27","slug":"colorectal-cancer-2","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/cancer-area\/molecular-mechanisms-and-experimental-therapy-in-oncology-program-oncobell\/colorectal-cancer-2\/","title":{"rendered":"Colorectal Cancer"},"content":{"rendered":"\n

\n\t\tColorectal cancer\n\t<\/h1>\n

\n\t\tSummary\n\t<\/h3>\n\t

The Colorectal Cancer (CRC) research group, led by V\u00edctor Moreno and Ramon Salazar, is focussed on discovering and validating new molecular signatures for diagnosis, prognosis and prediction, and identifying and optimising new therapeutic targets and molecular classifications of CRC, using an integromics approach, combining knowledge of genetic epidemiology, data bioinformatics and pharmacology.<\/p>\n

2760<\/h2>\n

Publications<\/h2>\n\t\t\t\t\"colorectal_adenocarcinoma_cytology_intermed_mag\n\t\t\t\t\tStrategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tMolecular characterisation of gastrointestinal tumours through genomic, transcriptomic and proteomic analysis (R. Salazar, V. Moreno).
\nConstruction of molecular signatures for predicting colorectal cancer prognosis (R. Salazar).
\nPredictions of therapeutic response based on molecular tumour detection and subtype classification (R. Salazar)
\nNew experimental therapeutic strategies to overcome resistance in colorectal cancer treatment (R. Salazar).
\nResearch, evaluation and validation of new diagnostic biomarkers in colorectal cancer (V. Moreno).
\nGenetic and epigenetic determinants of susceptibility to CRC and chemotherapy toxicity (V. Moreno).
\nImprovement in cancer precision medication and biomarker identification using computational analysis and large-scale integration of molecular data. (X. Sol\u00e9).
\nStratification of CRC patients based on molecular characteristics and the level of immune-cell infiltration of their tumours (C. Santos andR. Sanz-Pamplona).
\nMicrobiome-host interactions and colorectal cancer (V. Pimenoff, M. Obon, V. Moreno).
\nPrognostic and predictive values of circulating tumour DNA in metastatic colorectal cancer (C. Santos).\n\t\t\t\t\t
Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t