{"id":4194,"date":"2020-04-06T09:37:10","date_gmt":"2020-04-06T07:37:10","guid":{"rendered":"https:\/\/idibell.cat\/en\/?page_id=4194"},"modified":"2023-07-06T09:54:24","modified_gmt":"2023-07-06T07:54:24","slug":"bioinformatics","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/services\/scientific-and-technical-services\/bioinformatics\/","title":{"rendered":"Bioinformatics"},"content":{"rendered":"\n<h1>\n\t\tBioinformatics\n\t<\/h1>\n\t<p>The IDIBELL Bioinformatics Unit (IBU) started the activity in 2018. Its mission is to provide all researchers at the Bellvitge Campus scientific consulting, methodological support and technological resources on bioinformatics to enhance both the number and the quality of research projects where omics data are involved. We also offer standard services to external community.<\/p>\n<p>Our staff has over 15 years&#8217; experience in experimental design, omics and integrative data analyses, databases and ontologies management, pipelines and tools development, as well as a long experience in teaching formal education and training activities in the fields of omics data and bioinformatics.<\/p>\n<p>The IBU is member of the Tanslational Bioinformatics Network (TransBioNet) impulsed and coordinated by the Spanish National Bioinformatics Institute (INB) and participates on behalf of the IDIBELL in the activity of Barcelona Bioinformatics (BIB) and CERCA Institute.<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/bioinformatica.jpg\" alt=\"bioinformatica\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"bioinformatica\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Services<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>Please, fill out <a href=\"https:\/\/forms.office.com\/Pages\/ResponsePage.aspx?id=6GrqEBX-pkGKsj4DrzJGgWlxrLCX6M9EuMTjUa5XhuNUMEQ3NUhGSFBPSjBBOEhFRVhBQkFISldJUi4u\" target=\"_blank\" rel=\"noopener\">this form<\/a> to request inquiries and quotes or contact us by email (bioinformatics@idibell.cat) to resolve any other question or concern you may have.<\/p>\n<p>We assist researchers by providing:<\/p>\n<p><strong>Consultancy <\/strong><\/p>\n<ul>\n<li>Experimental design<\/li>\n<li>Bioinformatics methodology<\/li>\n<li>Bioinformatics software<\/li>\n<li>Grant application: service quotation, sample size, planning of methods, etc.<\/li>\n<li>Custom Service<\/li>\n<\/ul>\n<p><strong>Data analysis<\/strong><\/p>\n<ul>\n<li>Omics data: genomics, transcriptomics, epigenomics, proteomics, etc.<\/li>\n<li>Data mining and analysis using public datasets<\/li>\n<li>Combine clinical or biomedical information with omics data<\/li>\n<li>Construction of prediction\/classification models using learning techniques<\/li>\n<\/ul>\n<p><strong>Software development<\/strong><\/p>\n<ul>\n<li>Workflows or pipelines<\/li>\n<li>Databases and ontologies<\/li>\n<li>Custom tool<\/li>\n<\/ul>\n<p><strong>Training activities<\/strong><\/p>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Equipment<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>Currently, the computer resources of the unit consist of <\/p>\n<ul>\n<li>2 Workstations<\/li>\n<\/ul><ul>\n<li>HP Z240: 8 Intel core i7-770 CPU, 3.60GHz, 64GB RAM, 4TB HD<\/li>\n<li>HP Z2 G4: 8 Intel core i7-8700k CPU, 3.70GHz, 64GB RAM, 2TB HD<\/li>\n<\/ul>\n<li>2 Desktops<\/li>\n<ul>\n<li>HP ProDesk 600 G3 MT: 8 Intel core i7-770 CPU, 3.60GHz, 64GB RAM, 2TB HD<\/li>\n<li>DELL D05D001: 4 Intel core i5-2400 CPU, 3.40GHz, 6GB RAM, 250GB HD<\/li>\n<\/ul>\n<li>1 Laptop<\/li>\n<ul>\n<li>MackBook Air: dual-core Intel Core i5, 1.6GHz, 8GB RAM, 128GB SSD<\/li>\n<\/ul>\n<li>1 Network-Attached Sorage<\/li>\n<ul>\n<li>Synology Rackstation RS820RP+, 24TB HD<\/li>\n<\/ul>\n\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs00401-021-02387-z\" target=\"_blank\" rel=\"noopener\">DGCR8 and the six hit, three-step model of schwannomatosis.<\/a><br \/>\nNogu\u00e9 C, Chong AS, Grau E, Han H, Dorca E, Roca C, <strong>Mosquera JL<\/strong>, L\u00e1zaro C, Foulkes WD, Brunet J, Rivera B.<br \/>\nActa Neuropathologica (2021). doi: 10.1007\/s00401-021-02387-z\n<a href=\"https:\/\/www.nature.com\/articles\/s41467-021-24808-z\">Disruption of NIPBL\/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome.<\/a><br \/>\nGarcia P, Fernandez-Hernandez R, Cuadrado A, Coca I, Gomez A, <strong>Maqueda M<\/strong>, Latorre-Pellicer A, Puisac B, Ramos FJ, Sandoval J, Esteller M, <strong>Mosquera JL<\/strong>, Rodriguez J, Pi\u00e9 J, Losada A, Queralt E.<br \/>\nNature Communications 12:4551 (2021). doi:10.1038\/s41467-021-24808-z\n<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0142961221004051?via%3Dihub\">Repopulation of decellularized retinas with hiPSC-derived retinal pigment epithelial and ocular progenitor cells shows cell engraftment, organization and differentiation.<\/a><br \/>\n<strong>Maqueda M<\/strong>, <strong>Mosquera JL<\/strong>, Garc\u00eda-Arum\u00ed J, Veiga A, Duarri A.<br \/>\nBiomaterials 276:121049 (2021). doi:10.1016\/j.biomaterials.2021.121049\n<a href=\"http:\/\/genesdev.cshlp.org\/content\/35\/17-18\/1229\">REST is a major negative regulator of endocrine differentiation during pancreas organogenesis.<\/a><br \/>\nRovira M, Atla G, Maestro MA, Grau V, Garc\u00eda-Hurtado J, <strong>Maqueda M<\/strong>, <strong>Mosquera JL<\/strong>, Yamada Y, Kerr-Conte J, Pattou F, Ferrer J.<br \/>\nGenes &amp; Development 35:1229-1242 (2021). doi: 10.1101\/gad.348501.121\n<a href=\"https:\/\/www.mdpi.com\/2076-3921\/10\/12\/1936\" target=\"_blank\" rel=\"noopener\">Genome-Wide RNAi Screening Identifies Novel Pathways\/Genes Involved in Oxidative Stress and Repurposable Drugs to Preserve Cystic Fibrosis Airway Epithelial Cell Integrity.<\/a><br \/>\nCheca J, Mart\u00ednez-Gonz\u00e1lez I, <strong>Maqueda M<\/strong>, <strong>Mosquera JL<\/strong>, Aran JM.<br \/>\nAntioxidants 10(12):1936 (2021). doi:10.3390\/antiox10121936\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2019\/10\/avatar-188-150x150.jpeg\" alt=\"avatar-188\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"avatar-188\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tTBA\n\t<\/h4>\n<h4>\n\t\tCONTACT\n\t<\/h4>\n<h4>\n\t\tBioinformatics (TBA)\n\t<\/h4>\n\n<h4>\n\t\t<a href=\"mailto:vmoreno@idibell.cat\" title=\"\" target=\"_blank\" rel=\"noopener\">\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tDOCUMENTS\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/drive.google.com\/file\/d\/1v2V6HM77HkyaLqyQlLVJPJ56MmwUZ_cA\/view?usp=sharing\" title=\"Core Facilities Fees [pdf]\" target=\"_blank\" rel=\"noopener\">\n\t\tCore Facilities Fees [pdf]\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tHead of Unit\t\t\t\t<\/a>\n\t\t\t\t\t\tHead of Unit\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>TBA<\/li>\n<\/ul>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/plugins\/bb-plugin\/img\/pixel.png\" alt=\"\" itemprop=\"image\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/plugins\/bb-plugin\/img\/pixel.png\" alt=\"\" itemprop=\"image\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/plugins\/bb-plugin\/img\/pixel.png\" alt=\"\" itemprop=\"image\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/plugins\/bb-plugin\/img\/pixel.png\" alt=\"\" itemprop=\"image\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/plugins\/bb-plugin\/img\/pixel.png\" alt=\"\" itemprop=\"image\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/plugins\/bb-plugin\/img\/pixel.png\" alt=\"\" itemprop=\"image\" onerror=\"this.style.display='none'\"  \/>\n\n","protected":false},"excerpt":{"rendered":"<p>Bioinformatics The IDIBELL Bioinformatics Unit (IBU) started the activity in 2018. Its mission is to provide all researchers at the Bellvitge Campus scientific consulting, methodological support and technological resources on bioinformatics to enhance both the number and the quality of research projects where omics data are involved. We also offer standard services to external community. [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":679,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-4194","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2024-12-25 23:40:50","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/4194","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=4194"}],"version-history":[{"count":5,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/4194\/revisions"}],"predecessor-version":[{"id":22816,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/4194\/revisions\/22816"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/679"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=4194"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}