{"id":3968,"date":"2020-02-12T16:39:54","date_gmt":"2020-02-12T15:39:54","guid":{"rendered":"https:\/\/idibell.cat\/en\/?page_id=3968"},"modified":"2024-04-11T12:26:17","modified_gmt":"2024-04-11T10:26:17","slug":"stem-cell-potency","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/area-medicina-regenerativa-english\/regenerative-medicine-program\/stem-cell-potency\/","title":{"rendered":"Stem Cell Potency"},"content":{"rendered":"\n<h1>\n\t\tStem Cell Potency  \n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\t<p>During embryo development, the potency of the zygote is deployed through coordinated and stereotypical changes in cell behaviors and processes of tissue patterning, ultimately resulting in the formation of an entire, highly complex organism in a relatively short period of time. Throughout this process, the developmental potency of individual cells, i.e. their ability to give rise to cells of a different type than their own, is progressively lost, so that somatic cells in adult individuals retain very limited potency (such as in rare adult stem cells) or show no potency at all.<\/p>\n<p>Our laboratory is interested in understanding the mechanisms that govern the degree of potency of human somatic cells, and how it can be experimentally increased for conditions where doing so may be of biomedical relevance. Specifically, the context in which we investigate these issues is mainly centered on the paradigm of cardiac regeneration\/repair. Overall, our research takes advantage of a variety of experimental paradigms (zebrafish heart regeneration, human iPSC generation and differentiation), approached from a multi-disciplinary perspective, ranging from bioengineering approaches to 3D stem cell differentiation to single-cell genetic lineage tracing analyses and genetic manipulation of human cells, aimed at tackling important current issues in biology and biomedicine, such as the mechanisms that control the establishment and maintenance of developmental potency, the initiation and progression of the regenerative process, and the differentiation and functional maturation of human cardiomyocytes, and the development of genuinely human models of human disease.<\/p>\n<h2>204<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/Stem-Cell-Potency.png\" alt=\"Stem-Cell-Potency\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"Stem-Cell-Potency\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\tHeart regeneration in zebrafish<br \/>\niPSC-based disease modeling<br \/>\nCardiac tissue engineering<br \/>\nReprogramming strategies for heart repair\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>Montserrat Vazquez S, Ali NJ, Matteini F, Lozano J, Zhaowei T, Mejia Ramirez E, Marka G, Vollmer A, Soller K, Sacma M, Sakk V, Mularoni L, Mallm JP, Plass M, Zheng Y, Geiger H, Florian MC. <strong>Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice<\/strong>. npj Regen. Med. 2022;7(1):doi:10.1038\/s41536-022-00275-y.<\/p>\n<p>Mazuelas H, Magall\u00f3n Lorenz M, Fern\u00e1ndez Rodr\u00edguez J, Uriarte Arrazola I, Richaud Patin Y, Terribas E, Villanueva A, Castellanos E, Blanco I, Raya \u00c1, Chojnacki J, Heyn H, Romagosa C, L\u00e1zaro C, Gel B, Carri\u00f3 M, Serra E. <strong>Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas<\/strong>. Cell Rep. 2022;38(7):110385-110385. doi:10.1016\/j.celrep.2022.110385.<\/p>\n<p>\u00c1lvarez Palomo B, Veiga A, Raya A, Codinach M, Torrents S, Ponce Verdugo L, Rodriguez Aierbe C, Cuellar L, Alenda R, Arbona C, Hern\u00e1ndez Maraver D, Fust\u00e9 C, Querol S.<strong> Public Cord Blood Banks as a source of starting material for clinical grade HLA-homozygous induced pluripotent stem cells<\/strong>. Stem Cell Res. Ther. 2022;13(1):408-408. doi:10.1186\/s13287-022-02961-6.<\/p>\n<p>Dajani R, Jiwani B, Nanji A, Zoloth L, Ghaly M, Ilkili\u00e7 I, Raya \u00c1, Patr\u00e3o Neves M, de Melo H, Carvalho AS, Caulfield T, Carter R, Rendas A, Surani A, Rossant J, Kriegstein A, Lalani EN. <strong>Diversifying stem cell debates: Including Muslim contexts and perspectives.<\/strong> Stem Cell Reports. 2022;17(5):1019-1022. doi:10.1016\/j.stemcr.2022.03.008.<\/p>\n<p>Codina P, Domingo M, Barcel\u00f3 E, Gastelurrutia P, Casquete D, Vila J, Abdul Jawad Altisent O, Spitaleri G, Cediel G, Santiago Vacas E, Zamora E, Ruiz Cueto M, Santesmases J, de la Espriella R, Pascual Figal DA, Nu\u00f1ez J, Lup\u00f3n J, Bayes Genis A. <strong>Sacubitril\/valsartan affects pulmonary arterial pressure in heart failure with preserved ejection fraction and pulmonary hypertension<\/strong>. ESC Heart Fail. 2022;9(4):2170-2180. doi:10.1002\/ehf2.13952.<\/p>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>MCI21048. <strong>Estudio de las adaptaciones del microambiente que controlan la regeneraci\u00f3n\/reparaci\u00f3n cardiaca<\/strong>. Ministerio de Ciencia e Innovaci\u00f3n. Budget: 311938. 2022-2025. PI: RAYA CHAMORRO, ANGEL.<\/p>\n<p>20MEC003. <strong>Estudio de los mecanismos que relacionan las propiedades de la matrix extracelular y la regeneraci\u00f3n\/reparaci\u00f3n cardiaca<\/strong>. Ministerio de Ciencia e Innovaci\u00f3n. Budget: 268117,71. 2019-2022. PI: RAYA CHAMORRO, ANGEL.<\/p>\n<p>20FIS028. <strong>Red de Terapia Celular (TerCel)<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 240245,5. 2017-2022. PI: RAYA CHAMORRO, ANGEL.<\/p>\n<p>20MEC019. <strong>AYUDAS PARA LA FORMACION DE DOCTORES DEL PROGRAMA NACIONAL DE FORMACION DE PROFESORADO UNIVERSITARIO (FPU)<\/strong>. MINISTERIO DE EDUCACI\u00d3N Y FORMACI\u00d3N PROFESIONAL. Budget: 144048,76. 2020-2026. PI: RAYA CHAMORRO, ANGEL.<\/p>\n<p>20MEC014. <strong>AYUDAS PARA CONTRATOS PREDOCTORALES PARA LA FORMACI\u00d3N DE DOCTORES 2019<\/strong>. Ministerio de Ciencia e Innovaci\u00f3n. Budget: 95450. 2020-2023. PI: RAYA CHAMORRO, ANGEL.<\/p>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\">Technology transfer<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\"><i>Expand<\/i><\/a>\n\t\t\t\t\tPAT072-Composition for Improving the Culture and Implantation of Mammalian Embryos, Preparation Method and Use Thereof<br \/>\nIP: Samuel Ojosnegros (patent que es va incorpora al IDIBELL amb l&#8217;adquisici\u00f3 del CMRB)<br \/>\nEP 19382106\nLicense: Composition for improving the culture and implantation of mammalian embryos preparation method and use thereof<br \/>\nPI: Dr. \u00c1ngel Raya\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/02\/angel_royo-150x150.png\" alt=\"Raya Chamorro, \u00c1ngel\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Raya Chamorro, \u00c1ngel\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tRaya Chamorro, \u00c1ngel    \n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:araya@idibell.cat\" title=\"araya@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\taraya@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/02\/angel_royo-150x150.png\" alt=\"Raya Chamorro, \u00c1ngel\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Raya Chamorro, \u00c1ngel\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tRaya Chamorro, \u00c1ngel    \n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:araya@idibell.cat\" title=\"araya@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\taraya@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tRELATED LINKS\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/p-cmrc.cat\/\" title=\"P-CMR[C]\" target=\"_blank\" rel=\"noopener\">\n\t\tP-CMR[C]\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/p_cmrc\" title=\"@p_cmrc\" target=\"_blank\" rel=\"noopener\">\n\t\t@p_cmrc\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/www.icrea.cat\/Web\/ScientificStaff\/angel-raya--chamorro-354\" title=\"ICREA\" target=\"_blank\" rel=\"noopener\">\n\t\tICREA\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/www.ciber-bbn.es\/grupos\/grupo-de-investigacion?id=3618\" title=\"CIBER-BBN\" target=\"_blank\" rel=\"noopener\">\n\t\tCIBER-BBN\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.red-tercel.com\/grupo.asp?id=RD16\/0011\/0024\" title=\"RED-TERCEL\" target=\"_blank\" rel=\"noopener\">\n\t\tRED-TERCEL\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tScientific support\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-4\" data-index=\"4\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-4\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tManagement support\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Raya Chamorro, Angel<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers \n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Castillo Robles, Jorge Luis<\/li>\n<li>Litowczenko Cybulska, Jagoda Dominika<\/li>\n<li>Uribe Brange, Daniel Alejandro<\/li>\n<li>Boix Besora, Arnau<\/li>\n<li>Nieto Romero, Virginia<\/li>\n<li>Fredericksen Quilodran, Fernanda Valentina<\/li>\n<\/ul>\n\t\t\t\t\t\tPredoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Tadevosyan, Karine<\/li>\n<li>Lazis, Ioannis<\/li>\n<li>Casado Medina, Laura<\/li>\n<li>Yuan, Yang<\/li>\n<\/ul>\n\t\t\t\t\t\tScientific support\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Morillas Garc\u00eda, Alba<\/li>\n<li>Richaud Patin, Ivonne<\/li>\n<li>Garc\u00eda Pastor, Cristina<\/li>\n<li>Mularoni, Loris<\/li>\n<li>Jimenez Delgado, Senda<\/li>\n<li>Lorenzo Serrano, Edgar<\/li>\n<\/ul>\n\t\t\t\t\t\tManagement support\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Van Dongen, Maria Johanna<\/li>\n<li>Rodr\u00edguez Aguilar, Ester<\/li>\n<\/ul>\n<h2>\n\t\tRelated news\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" 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content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/NO20-Neurofibromes-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/02\/the-generation-of-a-stem-cell-derived-neurofibroma-model-opens-the-door-to-new-treatments-development\/\" title=\"The generation of a stem cell-derived neurofibroma model opens the door to new treatments development\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/02\/the-generation-of-a-stem-cell-derived-neurofibroma-model-opens-the-door-to-new-treatments-development\/\" title=\"The generation of a stem cell-derived neurofibroma model opens the door to new treatments development\">The generation of a stem cell-derived neurofibroma model opens the door to new treatments development<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t22\/02\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/17692\" content=\"Identified an early neuronal dysfunction in Parkinson&#8217;s that could help early diagnosis\" \/><meta itemprop=\"datePublished\" content=\"2021-07-06\" \/><meta itemprop=\"dateModified\" content=\"2021-07-06\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/07\/NO61-Consiglio_NPJ-Imatge-capcalera.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/07\/identified-an-early-neuronal-dysfunction-in-parkinsons-that-could-help-early-diagnosis\/\" title=\"Identified an early neuronal dysfunction in Parkinson&#8217;s that could help early diagnosis\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/07\/identified-an-early-neuronal-dysfunction-in-parkinsons-that-could-help-early-diagnosis\/\" title=\"Identified an early neuronal dysfunction in Parkinson&#8217;s that could help early diagnosis\">Identified an early neuronal dysfunction in Parkinson&#8217;s that could help early diagnosis<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  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\/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/06\/the-p-cmrc-launches-its-website\/\" title=\"The P-CMR[C] launches its website\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/06\/the-p-cmrc-launches-its-website\/\" title=\"The P-CMR[C] launches its website\">The P-CMR[C] launches its website<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t09\/06\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/4939\" content=\"IDIBELL researchers Antonella Consiglio and \u00c1ngel Raya, awarded with the City of Barcelona Award\" \/><meta itemprop=\"datePublished\" content=\"2020-01-28\" \/><meta itemprop=\"dateModified\" content=\"2023-11-22\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/foto_entrega_premi-1.jpg\" \/><meta itemprop=\"width\" content=\"1024\" \/><meta itemprop=\"height\" content=\"576\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/01\/idibell-researchers-antonella-consiglio-and-angel-raya-awarded-with-the-city-of-barcelona-award\/\" title=\"IDIBELL researchers Antonella Consiglio and \u00c1ngel Raya, awarded with the City of Barcelona Award\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/01\/idibell-researchers-antonella-consiglio-and-angel-raya-awarded-with-the-city-of-barcelona-award\/\" title=\"IDIBELL researchers Antonella Consiglio and \u00c1ngel Raya, awarded with the City of Barcelona Award\">IDIBELL researchers Antonella Consiglio and \u00c1ngel Raya, awarded with the City of Barcelona Award<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t28\/01\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/4981\" content=\"Resolution of the Call for Expression of Interest (EoI) for Collaborative Projects on Regenerative Medicine 2019\" \/><meta itemprop=\"datePublished\" content=\"2019-11-27\" \/><meta itemprop=\"dateModified\" content=\"2020-05-29\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/marca-a_1-1-scaled.jpg\" \/><meta itemprop=\"width\" content=\"2560\" \/><meta itemprop=\"height\" content=\"1811\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2019\/11\/resolution-of-the-call-for-expression-of-interest-eoi-for-collaborative-projects-on-regenerative-medicine-2019\/\" title=\"Resolution of the Call for Expression of Interest (EoI) for Collaborative Projects on Regenerative Medicine 2019\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2019\/11\/resolution-of-the-call-for-expression-of-interest-eoi-for-collaborative-projects-on-regenerative-medicine-2019\/\" title=\"Resolution of the Call for Expression of Interest (EoI) for Collaborative Projects on Regenerative Medicine 2019\">Resolution of the Call for Expression of Interest (EoI) for Collaborative Projects on Regenerative Medicine 2019<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t27\/11\/2019\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Stem Cell Potency Summary During embryo development, the potency of the zygote is deployed through coordinated and stereotypical changes in cell behaviors and processes of tissue patterning, ultimately resulting in the formation of an entire, highly complex organism in a relatively short period of time. Throughout this process, the developmental potency of individual cells, i.e. [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":3911,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"publishpress_future_action":{"enabled":false,"date":"2024-05-11 11:14:21","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/3968"}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=3968"}],"version-history":[{"count":6,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/3968\/revisions"}],"predecessor-version":[{"id":23921,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/3968\/revisions\/23921"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/3911"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=3968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}