{"id":2949,"date":"2019-10-09T19:39:32","date_gmt":"2019-10-09T17:39:32","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2949"},"modified":"2025-05-28T15:33:26","modified_gmt":"2025-05-28T13:33:26","slug":"innate-immunity-and-pathology-of-the-critical-patient","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/translational-medicine-area\/infectious-disease-and-transplantation-program\/innate-immunity-and-pathology-of-the-critical-patient\/","title":{"rendered":"Innate Immunity and Pathology of the Critical patient"},"content":{"rendered":"\n<h1>\n\t\tInnate immunity and pathology of the critical patient\n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\t<p>This group studies the immune system mechanisms related to transplants, sepsis and postoperative recovery following complex surgery (heart surgery, for example). It also studies the impact of these mechanisms in improving clinical activities, as well as other factors affecting the prognosis and clinical course of critically ill patients.<\/p>\n<h2>520<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/ucihospital.jpeg\" alt=\"ucihospital\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"ucihospital\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\tInnate immunity in xenotransplantation and in regenerative medicine<br \/>\nNatural antibody depletion as a mechanism of increasing immunity<br \/>\nInflammatory response in sepsis<br \/>\nPrognostic factors in neurocritical disease<br \/>\nPrognostic factors in the immediate postoperative period following heart surgery<br \/>\nRenal dysfunction in critically ill patients\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Galli,F;Bindo,F;Motos,A;Fernandez Barat,L;Barbeta,E;Gabarrus,A;Ceccato,A et al, <strong>Procalcitonin and C-reactive protein to rule out early bacterial coinfection in COVID-19 critically ill patients<\/strong>, Intensive Care Med., 2023;49(8):934-945, doi:10.1007\/s00134-023-07161-1<\/li>\n<li>Riera,J;Barbeta,E;Tormos,A;Mellado Artigas,R;Ceccato,A;Motos,A;Fernandez Barat,L et al, <strong>Effects of intubation timing in patients with COVID-19 throughout the four waves of the pandemic: a matched analysis<\/strong>, Eur. Resp. J., 2023;61(3)\u00a0 doi:10.1183\/13993003.01426-2022<\/li>\n<li>P\u00e9rez Galera,S;Bravo Ferrer,JM;Paniagua,M;Kostyanev,T;de Kraker,M;Feifel,J;Sojo Dorado,J et al, <strong>Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)<\/strong>., EClinicalMedicine, 2023;57101871-101871, doi:10.1016\/j.eclinm.2023.101871<\/li>\n<li>Matuozzo,D;Talouarn,E;Marchal,A;Zhang,P;Manry,J;Seeleuthner,Y;Zhang,Y et al, <strong>Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19<\/strong>., Genome Med., 2023;15(1):22-22, doi:10.1186\/s13073-023-01173-8<\/li>\n<li>Olivera Ardid,S;Bello Gil,D;Perez Cruz,M;Costa,C;Camoez,M;Dominguez,MA;Ferrero Alves,Y et al, <strong>Removal of natural anti-aGal antibodies elicits protective immunity against Gram-negative bacterial infections<\/strong>, Front. Immunol., 2023;141232924-1232924, doi:10.3389\/fimmu.2023.1232924<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>101045956.\u00a0COVend: Biomarker and AI-supported FX06 therapy to prevent progression from mild and moderate to severe stages of COVID-19. COMISSI\u00d3 EUROPEA. Budget: 114.101,66\u20ac. 2021-2024. PI: M\u00e1\u00f1ez Mendiluce, Rafael.<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\">Technology transfer<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-3\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<p>Licenses:<\/p>\n<ul>\n<li>METHOD AND KIT FOR THE EARLY DETECTION OF SEPSIS<br \/>\nPI: Dr. Joan Sabater&#8221;<\/li>\n<li>Methods and reagents for prevention and\/or treatment of infection (PAT049)<br \/>\nPI: Dr. Rafael M\u00e1\u00f1ez<\/li>\n<\/ul>\n<p>Spin-off:<\/p>\n<ul>\n<li>RemAb Therapeutics<br \/>\nPI: Dr. Rafael M\u00e1\u00f1ez<\/li>\n<\/ul>\n<p>Patents;<\/p>\n<ul>\n<li>PAT082-M\u00c9TODO Y KIT PARA LA DETECCI\u00d3N TEMPRANA DE SEPSIS<br \/>\nIP: Joan Sabater<br \/>\nEP 20382462<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-4\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-4\">More information<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-4\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<p><i>Proyectos financiados por el Instituto de Salud Carlos III (ISCIII) y cofinanciados por el Fondo Europeo de Desarrollo Regional (FEDER):<\/i><\/p>\n<p>\u00a0<\/p>\n<p><b>Papel de los Anticuerpos Anti-Acido Hialur\u00f3nico y de la Inmunidad Innata Celular en el Deterioro Estructural Valvular de Pr\u00f3tesis Cardiacas Biol\u00f3gicas<\/b><\/p>\n<p>PI13\/01098. 01\/2014-12\/2016. 57.500 \u20ac. IP: Rafael M\u00e1\u00f1ez Mendiluce.<\/p>\n<p>Analizar el papel de la xenoinmunidad y autoinmunidad en el desarrollo de deterioro estructural valvular (DEV), en v\u00e1lvulas card\u00edacas biol\u00f3gicas a\u00f3rticas de origen porcino y bovino. Estudiar la inmunidad innata humoral (anticuerpos naturales contra oligosac\u00e1ridos del \u00e1cido hialur\u00f3nico) y celular mediada por macr\u00f3fagos y c\u00e9lulas NK, y el potencial papel de las mismas en el desarrollo de DEV.<\/p>\n<p>\u00a0<\/p>\n<p><b>Estudio precl\u00ednico y traslacional de nuevos agentes anticancerosos derivados de tambjaminas para el tratamiento del c\u00e1ncer de pulm\u00f3n humano<\/b><\/p>\n<p>\u00a0<\/p>\n<p>PI13\/00089. 01\/2014-12\/2016. 57.500 \u20ac. IP: Ricardo P\u00e9rez Tom\u00e1s.<\/p>\n<p>Identificar nuevas mol\u00e9culas m\u00e1s eficaces para combatir el c\u00e1ncer de pulm\u00f3n, bajo diversas perspectivas como son la qu\u00edmica m\u00e9dica, formulaci\u00f3n de nuevos f\u00e1rmacos, simulaci\u00f3n computacional, biolog\u00eda celular in vitro y t\u00e9cnicas bioqu\u00edmicas, transcript\u00f3mica y an\u00e1lisis de prote\u00f3mica, as\u00ed como en investigaci\u00f3n traslacional en modelos de xenotrasplante, permitir\u00e1 que seamos capaces de completar con \u00e9xito los estudios precl\u00ednicos de una prometedora nueva familia de compuestos anticancerosos. La desregulaci\u00f3n del pH es una caracter\u00edstica com\u00fan que confiere ventajas adaptativas a las c\u00e9lulas cancerosas. Proponemos que mol\u00e9culas que selectivamente poseen la capacidad de disminuir el pH intracelular ser\u00edan de gran inter\u00e9s como nuevos agentes quimioterap\u00e9uticos para el tratamiento del c\u00e1ncer de pulm\u00f3n. Evaluar la seguridad y eficacia de estos compuestos in vivo, desarrollar una innovadora nanoformulaci\u00f3n farmacol\u00f3gica con el fin de mejorar la selectividad y la eficacia, as\u00ed como ensayar una nueva y prometedora v\u00eda de administraci\u00f3n del f\u00e1rmaco.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/03\/7mUdUAq.png\" alt=\"\" width=\"249\" height=\"150\" \/><\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/11\/Rafael-Manez22-150x150.jpg\" alt=\"Rafael-Ma\u00f1ez22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Rafael-Ma\u00f1ez22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMa\u00f1ez Mendiluce, Rafael\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:rmanez@idibell.cat\" title=\"rmanez@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\trmanez@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/11\/Rafael-Manez22-150x150.jpg\" alt=\"Rafael-Ma\u00f1ez22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Rafael-Ma\u00f1ez22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMa\u00f1ez Mendiluce, Rafael\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:rmanez@idibell.cat\" title=\"rmanez@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\trmanez@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img decoding=\"async\" src=\"https:\/\/idibell.cat\/wp-content\/uploads\/2019\/09\/avatar-150x150.jpeg\" alt=\"avatar\" itemprop=\"image\" title=\"avatar\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tSabater Riera, Joan\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:jsabater@idibell.cat\" title=\"jsabater@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\tjsabater@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup Leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPrincipal investigators\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tClinical researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-4\" data-index=\"4\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-4\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup Leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Ma\u00f1ez Mendiluce, Rafael<\/li>\n<\/ul>\n\t\t\t\t\t\tPrincipal investigators\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Sabater Riera, Joan<\/li>\n<\/ul>\n\t\t\t\t\t\tClinical researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Corral Ansa, Luisa<\/li>\n<li>Esteve Urbano, Francesc<\/li>\n<li>Fuset Cabanes, M\u00aa Paz<\/li>\n<li>Moreno Gonz\u00e1lez, Gabriel Jesus<\/li>\n<li>Ochagavia Calvo, Ana<\/li>\n<li>Oliver Juan, Eva<\/li>\n<li>P\u00e9rez Fern\u00e1ndez, Xos\u00e9 Luis<\/li>\n<li>Ulsamer Riera, Arnau<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Olivera Ardid, Sara<\/li>\n<\/ul>\n\t\t\t\t\t\tPredoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Gumucio Sanguino, Victor Daniel<\/li>\n<\/ul>\n<h2>\n\t\tRelated news\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/24684\" content=\"A study published in JAMA shows the good results of a new extracorporeal blood purification membrane\" \/><meta itemprop=\"datePublished\" content=\"2024-10-23\" \/><meta itemprop=\"dateModified\" content=\"2024-10-23\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2024\/10\/Equip-de-professionals-de-Cirurgia-Cardiaca-que-han-participat-a-lestudi-WEB.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"769\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/10\/a-study-published-in-jama-shows-the-good-results-of-a-new-extracorporeal-blood-purification-membrane\/\" title=\"A study published in JAMA shows the good results of a new extracorporeal blood purification membrane\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/10\/a-study-published-in-jama-shows-the-good-results-of-a-new-extracorporeal-blood-purification-membrane\/\" title=\"A study published in JAMA shows the good results of a new extracorporeal blood purification membrane\">A study published in JAMA shows the good results of a new extracorporeal blood purification membrane<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t23\/10\/2024\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/24463\" content=\"Dr. Gabriela Abelenda receives a Juan Rod\u00e9s postdoctoral scholarship for her research on respiratory infections\" \/><meta itemprop=\"datePublished\" content=\"2024-07-19\" \/><meta itemprop=\"dateModified\" content=\"2024-07-19\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2024\/07\/Gabriela-Abelenda_240717_03_16-9-1.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/07\/dr-gabriela-abelenda-receives-a-juan-rodes-postdoctoral-scholarship-for-her-research-on-respiratory-infections\/\" title=\"Dr. Gabriela Abelenda receives a Juan Rod\u00e9s postdoctoral scholarship for her research on respiratory infections\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/07\/dr-gabriela-abelenda-receives-a-juan-rodes-postdoctoral-scholarship-for-her-research-on-respiratory-infections\/\" title=\"Dr. Gabriela Abelenda receives a Juan Rod\u00e9s postdoctoral scholarship for her research on respiratory infections\">Dr. Gabriela Abelenda receives a Juan Rod\u00e9s postdoctoral scholarship for her research on respiratory infections<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t19\/07\/2024\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/22324\" content=\"IDIBELL&#8217;s technology, licensed to LoopDx, starts a crowdequity campaign\" \/><meta itemprop=\"datePublished\" content=\"2023-03-24\" \/><meta itemprop=\"dateModified\" content=\"2023-03-28\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2023\/03\/NO035-Financament-LoopDx-Imatge-noti.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/03\/idibells-technology-licensed-to-loopdx-starts-a-crowdequity-campaign\/\" title=\"IDIBELL&#8217;s technology, licensed to LoopDx, starts a crowdequity campaign\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/03\/idibells-technology-licensed-to-loopdx-starts-a-crowdequity-campaign\/\" title=\"IDIBELL&#8217;s technology, licensed to LoopDx, starts a crowdequity campaign\">IDIBELL&#8217;s technology, licensed to LoopDx, starts a crowdequity campaign<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t24\/03\/2023\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/19700\" content=\"Two naturally occurring antibodies are responsible for the deterioration of valvular heart implants of animal origin\" \/><meta itemprop=\"datePublished\" content=\"2022-02-17\" \/><meta itemprop=\"dateModified\" content=\"2022-02-17\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/NP03-R-Manez_Nat-Med-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/02\/two-naturally-occurring-antibodies-are-responsible-for-the-deterioration-of-valvular-heart-implants-of-animal-origin\/\" title=\"Two naturally occurring antibodies are responsible for the deterioration of valvular heart implants of animal origin\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/02\/two-naturally-occurring-antibodies-are-responsible-for-the-deterioration-of-valvular-heart-implants-of-animal-origin\/\" title=\"Two naturally occurring antibodies are responsible for the deterioration of valvular heart implants of animal origin\">Two naturally occurring antibodies are responsible for the deterioration of valvular heart implants of animal origin<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t17\/02\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/16077\" content=\"IDIBELL researchers identify three clinical profiles of patients with COVID-19 with prognostic implications\" \/><meta itemprop=\"datePublished\" content=\"2021-03-09\" \/><meta itemprop=\"dateModified\" content=\"2021-03-09\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/03\/Covid_19_Bellvitge_2.jpg\" \/><meta itemprop=\"width\" content=\"640\" \/><meta itemprop=\"height\" content=\"360\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/03\/idibell-researchers-identify-three-clinical-profiles-of-patients-with-covid-19-with-prognostic-implications\/\" title=\"IDIBELL researchers identify three clinical profiles of patients with COVID-19 with prognostic implications\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/03\/idibell-researchers-identify-three-clinical-profiles-of-patients-with-covid-19-with-prognostic-implications\/\" title=\"IDIBELL researchers identify three clinical profiles of patients with COVID-19 with prognostic implications\">IDIBELL researchers identify three clinical profiles of patients with COVID-19 with prognostic implications<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t09\/03\/2021\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/15328\" content=\"Bellvitge will study the application of artificial intelligence in the treatment of Covid-19 in ICUs\" \/><meta itemprop=\"datePublished\" content=\"2020-11-18\" \/><meta itemprop=\"dateModified\" content=\"2021-03-04\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Unitat-de-Cures-Intensives-de-lHospital-de-Bellvitge-1.jpg\" \/><meta itemprop=\"width\" content=\"1000\" \/><meta itemprop=\"height\" content=\"667\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/11\/bellvitge-will-study-the-application-of-artificial-intelligence-in-the-treatment-of-covid-19-in-icus\/\" title=\"Bellvitge will study the application of artificial intelligence in the treatment of Covid-19 in ICUs\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/11\/bellvitge-will-study-the-application-of-artificial-intelligence-in-the-treatment-of-covid-19-in-icus\/\" title=\"Bellvitge will study the application of artificial intelligence in the treatment of Covid-19 in ICUs\">Bellvitge will study the application of artificial intelligence in the treatment of Covid-19 in ICUs<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t18\/11\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/4888\" content=\"The health department will finance 3 IDIBELL's projects on COVID-19\" \/><meta itemprop=\"datePublished\" content=\"2020-04-08\" \/><meta itemprop=\"dateModified\" content=\"2020-08-07\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/NO17-Foto-Composici\u00f3.jpg\" \/><meta itemprop=\"width\" content=\"2143\" \/><meta itemprop=\"height\" content=\"1125\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/04\/the-health-department-will-finance-3-idibells-projects-on-covid-19\/\" title=\"The health department will finance 3 IDIBELL's projects on COVID-19\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/04\/the-health-department-will-finance-3-idibells-projects-on-covid-19\/\" title=\"The health department will finance 3 IDIBELL's projects on COVID-19\">The health department will finance 3 IDIBELL&#8217;s projects on COVID-19<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t08\/04\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/4894\" content=\"An alternative drug to antibiotics receives the boost from the CaixaImpulse Consolidate program\" \/><meta itemprop=\"datePublished\" content=\"2020-03-23\" \/><meta itemprop=\"dateModified\" content=\"2020-08-07\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/rafel_manez-1.jpg\" \/><meta itemprop=\"width\" content=\"1455\" \/><meta itemprop=\"height\" content=\"1370\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/03\/an-alternative-drug-to-antibiotics-receives-the-boost-from-the-caixaimpulse-consolidate-program\/\" title=\"An alternative drug to antibiotics receives the boost from the CaixaImpulse Consolidate program\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/03\/an-alternative-drug-to-antibiotics-receives-the-boost-from-the-caixaimpulse-consolidate-program\/\" title=\"An alternative drug to antibiotics receives the boost from the CaixaImpulse Consolidate program\">An alternative drug to antibiotics receives the boost from the CaixaImpulse Consolidate program<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t23\/03\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5105\" content=\"SeptiLoop receives \u20ac 100,000 to develop a rapid diagnostic kit for sepsis\" \/><meta itemprop=\"datePublished\" content=\"2019-05-29\" \/><meta itemprop=\"dateModified\" content=\"2020-10-29\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/logo_loop_diagnostics-1.jpg\" \/><meta itemprop=\"width\" content=\"2480\" \/><meta itemprop=\"height\" content=\"1728\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2019\/05\/septiloop-receives-e-100000-to-develop-a-rapid-diagnostic-kit-for-sepsis\/\" title=\"SeptiLoop receives \u20ac 100,000 to develop a rapid diagnostic kit for sepsis\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2019\/05\/septiloop-receives-e-100000-to-develop-a-rapid-diagnostic-kit-for-sepsis\/\" title=\"SeptiLoop receives \u20ac 100,000 to develop a rapid diagnostic kit for sepsis\">SeptiLoop receives \u20ac 100,000 to develop a rapid diagnostic kit for sepsis<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t29\/05\/2019\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5154\" content=\"IDIBELL and Bellvitge University Hospital develop a new treatment to fight against hospital infections\" \/><meta itemprop=\"datePublished\" content=\"2018-12-13\" \/><meta itemprop=\"dateModified\" content=\"2020-08-07\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/rafael_manez-1.jpg\" \/><meta itemprop=\"width\" content=\"2016\" \/><meta itemprop=\"height\" content=\"1512\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/12\/idibell-and-bellvitge-university-hospital-develop-a-new-treatment-to-fight-against-hospital-infections\/\" title=\"IDIBELL and Bellvitge University Hospital develop a new treatment to fight against hospital infections\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/12\/idibell-and-bellvitge-university-hospital-develop-a-new-treatment-to-fight-against-hospital-infections\/\" title=\"IDIBELL and Bellvitge University Hospital develop a new treatment to fight against hospital infections\">IDIBELL and Bellvitge University Hospital develop a new treatment to fight against hospital infections<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t13\/12\/2018\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Innate immunity and pathology of the critical patient Summary This group studies the immune system mechanisms related to transplants, sepsis and postoperative recovery following complex surgery (heart surgery, for example). It also studies the impact of these mechanisms in improving clinical activities, as well as other factors affecting the prognosis and clinical course of critically [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":581,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-2949","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2025-06-09 12:04:54","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=2949"}],"version-history":[{"count":1,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2949\/revisions"}],"predecessor-version":[{"id":25848,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2949\/revisions\/25848"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/581"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=2949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}