{"id":2682,"date":"2019-10-07T15:10:19","date_gmt":"2019-10-07T13:10:19","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2682"},"modified":"2024-06-11T10:11:51","modified_gmt":"2024-06-11T08:11:51","slug":"modeling-human-diseases-in-c-elegans","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/translational-medicine-area\/genes-disease-and-therapy-program\/modeling-human-diseases-in-c-elegans\/","title":{"rendered":"Modeling human diseases in C. elegans"},"content":{"rendered":"\n<h1>\n\t\tModeling human diseases in C. elegans\n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\t<p>We use the model organism Caernorhabditis elegans for modeling human diseases. Our group has investigated genes involved in RNA processing that are altered in rare diseases or cancer. Thanks to CRISPR technologies, we are moving towards personalized medicine by mimicking human mutations in <em>C. elegans<\/em>. Moreover, we are taking advantages of the <em>C. elegans<\/em> feasibility for CRISPR genome editing to develop more efficient and versatile methodologies to edit genetic loci.<\/p>\n<h2>34<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/07\/Modeling-human-diseases-in-C-elegans2.png\" alt=\"Modeling-human-diseases-in-C-elegans2\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"Modeling-human-diseases-in-C-elegans2\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\tModeling rare diseases<br \/>\nCancer modelling<br \/>\nCRISPR genome editing\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Serrano,I;Luque,A;Ruiz Cerulla,A;Navas,S;Blom,AM;de C\u00f3rdoba,SR;Fern\u00e1ndez,FJ et al, <strong>C4BP(\u00df-)-mediated immunomodulation attenuates inflammation in DSS-induced murine colitis and in myeloid cells from IBD patients<\/strong>, Pharmacol. Res., 2023;197106948-106948, doi:10.1016\/j.phrs.2023.106948<\/li>\n<li>Vicencio J, S\u00e1nchez Bola\u00f1os C, Moreno S\u00e1nchez I, Brena D, Vejnar CE, Kukhtar D, Ruiz L\u00f3pez M, Cots Ponjoan M, Rubio A, Melero NR, Crespo Cuadrado J, Carolis C, P\u00e9rez Pulido AJ, Gir\u00e1ldez AJ, Kleinstiver BP, Cer\u00f3n J, Moreno Mateos MA. <strong>Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes.<\/strong> Nat. Commun. 2022;13(1):2601-2601. doi:10.1038\/s41467-022-30228-4.<\/li>\n<li>Mart\u00ednez Fern\u00e1ndez C, Bergamino M, Schiavi A, Brena D, Ventura N, Honnen S, Villanueva A, Nadal E, Cer\u00f3n J. <strong>Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans.<\/strong> Dis. Model. Mech. 2022;15(3):doi:10.1242\/dmm.049161.<\/li>\n<li>Jungtrakoon Thamtarana P, Marucci A, Pannone L, Bonnefond A, Pezzilli S, Biagini T, Buranasupkajorn P, Hastings T, Mendonca C, Marselli L, Di Paola R, Abubakar Z, Mercuri L, Alberico F, Flex E, Cer\u00f2n J, Porta Riva M, Ludovico O, Carella M, Martinelli S, Marchetti P, Mazza T, Froguel P, Trischitta V, Doria A, Prudente S. <strong>Gain of function of Malate Dehydrogenase 2 (MDH2) and familial hyperglycemia.<\/strong> J. Clin. Endocrinol. Metab. 2022;107(3):668-684. doi:10.1210\/clinem\/dgab790.<\/li>\n<li>Saura Esteller J, Sanchez Vera I, Nunez Vazquez S, Jabalquinto Carrasco J, Cosialls AM, Mendive Tapia L, Kukhtar D, Martinez Bueno MD, Lavilla R, Ceron J, Artal Sanz M, Pons G, Iglesias Serret D, Gil J. <strong>Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.<\/strong> Apoptosis. 2021;26(1-2):83-95. doi:10.1007\/s10495-020-01651-z.<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>21FIS019. <strong>Caracterizaci\u00f3n, potencial diagn\u00f3stico y terape\u00fatico de un nuevo inmunomodulador biol\u00f3gico para el tratamiento de enfermedades autoinmunes<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 171.820\u20ac. 2021-2023. PI: Aran Perramon, Josep M\u00aa.<\/li>\n<li>AGA21005. <strong>PROGRAMA BEATRIU DE PINOS 2020<\/strong>. AGENCIA GESTIO D&#8217;AJUTS UNIV. I RECERCA. Budget: 144.300\u20ac. 2022-2025. PI: Aran Perramon, Josep M\u00aa.<\/li>\n<li>21FIS011. <strong>Desarrollo de un nuevo biol\u00f3gico restaurador de la tolerancia inmunitaria. Aplicaci\u00f3n al tratamiento de la enfermedad inflamatoria intestinal<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 115.500\u20ac. 2021-2023. PI: Aran Perramon, Josep M\u00aa.<\/li>\n<li>FIS21142. <strong>CONTRATOS SARA BORRELL<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 95.000\u20ac. 2022-2022. PI: Aran Perramon, Josep M\u00aa.<\/li>\n<li>AGA22021. <strong>PurPose Biotherapeutics: first-in-class metabolic modulators against autoimmune diseases<\/strong>. AGENCIA GESTIO D&#8217;AJUTS UNIV. I RECERCA. Budget: 84.000,06\u20ac. 2022-2024. PI: Aran Perramon, Josep M\u00aa.<\/li>\n<\/ul>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/11\/Julian-Ceron22-150x150.jpg\" alt=\"Juli\u00e1n-Cer\u00f3n22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Juli\u00e1n-Cer\u00f3n22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tCer\u00f3n Madrigal, Juli\u00e1n\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:jceron@idibell.cat\" title=\"jceron@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tjceron@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/11\/Julian-Ceron22-150x150.jpg\" alt=\"Juli\u00e1n-Cer\u00f3n22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Juli\u00e1n-Cer\u00f3n22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tCer\u00f3n Madrigal, Juli\u00e1n\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:vmoreno@idibell.cat\" title=\"jceron@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tjceron@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tRELATED LINKS\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.ceronlab.com\/\" title=\"Ceronlab\" target=\"_blank\" rel=\"noopener\">\n\t\tCeronlab\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/CeronLab\" title=\"@CeronLab\" target=\"_blank\" rel=\"noopener\">\n\t\t@CeronLab\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tScientific support\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Cer\u00f3n Madrigal, Juli\u00e1n<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Aristizabal Corrales, David<\/li>\n<\/ul>\n\t\t\t\t\t\tScientific support\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Olaso Llorca, Alba<\/li>\n<\/ul>\n<h2>\n\t\tRelated news\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/20555\" content=\"A new system expands the gene-editing possibilities in animals\" \/><meta itemprop=\"datePublished\" content=\"2022-05-12\" \/><meta itemprop=\"dateModified\" content=\"2022-05-12\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" 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cells\">Humanizing worms makes them sensitive to a cancer drug and identifies weak points of tumor cells<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t24\/10\/2019\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5144\" content=\"The novel method Nested CRISPR enables efficient genome editing using long DNA fragments\" \/><meta itemprop=\"datePublished\" content=\"2019-02-07\" \/><meta itemprop=\"dateModified\" content=\"2020-05-14\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/recurso_nested_crispr-1.png\" \/><meta itemprop=\"width\" content=\"2539\" \/><meta itemprop=\"height\" content=\"1396\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2019\/02\/the-novel-method-nested-crispr-enables-efficient-genome-editing-using-long-dna-fragments\/\" title=\"The novel method Nested CRISPR enables efficient genome editing using long DNA fragments\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2019\/02\/the-novel-method-nested-crispr-enables-efficient-genome-editing-using-long-dna-fragments\/\" title=\"The novel method Nested CRISPR enables efficient genome editing using long DNA fragments\">The novel method Nested CRISPR enables efficient genome editing using long DNA fragments<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t07\/02\/2019\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5208\" content=\"ONCE and the Bellvitge Biomedical Research Institute (IDIBELL) renew their collaboration to study hereditary dystrophies of the retina\" \/><meta itemprop=\"datePublished\" content=\"2018-09-26\" \/><meta itemprop=\"dateModified\" content=\"2020-05-18\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/rp-5-1.jpg\" \/><meta itemprop=\"width\" content=\"500\" \/><meta itemprop=\"height\" content=\"288\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/09\/once-and-the-bellvitge-biomedical-research-institute-idibell-renew-their-collaboration-to-study-hereditary-dystrophies-of-the-retina\/\" title=\"ONCE and the Bellvitge Biomedical Research Institute (IDIBELL) renew their collaboration to study hereditary dystrophies of the retina\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/09\/once-and-the-bellvitge-biomedical-research-institute-idibell-renew-their-collaboration-to-study-hereditary-dystrophies-of-the-retina\/\" title=\"ONCE and the Bellvitge Biomedical Research Institute (IDIBELL) renew their collaboration to study hereditary dystrophies of the retina\">ONCE and the Bellvitge Biomedical Research Institute (IDIBELL) renew their collaboration to study hereditary dystrophies of the retina<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t26\/09\/2018\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5236\" content=\"CRISPR-editing of a single aminoacid make a whole animal more resistant to cisplatin-based chemotherapy\" \/><meta itemprop=\"datePublished\" content=\"2018-06-22\" \/><meta itemprop=\"dateModified\" content=\"2020-05-05\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/gusano-2-1.jpg\" \/><meta itemprop=\"width\" content=\"1388\" \/><meta itemprop=\"height\" content=\"828\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/06\/crispr-editing-of-a-single-aminoacid-make-a-whole-animal-more-resistant-to-cisplatin-based-chemotherapy\/\" title=\"CRISPR-editing of a single aminoacid make a whole animal more resistant to cisplatin-based chemotherapy\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/06\/crispr-editing-of-a-single-aminoacid-make-a-whole-animal-more-resistant-to-cisplatin-based-chemotherapy\/\" title=\"CRISPR-editing of a single aminoacid make a whole animal more resistant to cisplatin-based chemotherapy\">CRISPR-editing of a single aminoacid make a whole animal more resistant to cisplatin-based chemotherapy<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t22\/06\/2018\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5379\" content=\"IDIBELL will foster three INPhINIT young researchers\" \/><meta itemprop=\"datePublished\" content=\"2017-07-31\" \/><meta itemprop=\"dateModified\" content=\"2020-05-29\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/20170801_Ceron_Fdez_INPhINIT-1.jpg\" \/><meta itemprop=\"width\" content=\"350\" \/><meta itemprop=\"height\" content=\"214\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2017\/07\/idibell-will-foster-three-inphinit-young-researchers\/\" title=\"IDIBELL will foster three INPhINIT young researchers\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2017\/07\/idibell-will-foster-three-inphinit-young-researchers\/\" title=\"IDIBELL will foster three INPhINIT young researchers\">IDIBELL will foster three INPhINIT young researchers<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t31\/07\/2017\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Modeling human diseases in C. elegans Summary We use the model organism Caernorhabditis elegans for modeling human diseases. Our group has investigated genes involved in RNA processing that are altered in rare diseases or cancer. Thanks to CRISPR technologies, we are moving towards personalized medicine by mimicking human mutations in C. elegans. Moreover, we are [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":552,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-2682","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2024-12-25 12:20:53","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=2682"}],"version-history":[{"count":7,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2682\/revisions"}],"predecessor-version":[{"id":24268,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2682\/revisions\/24268"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/552"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=2682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}