{"id":2579,"date":"2019-10-06T21:21:19","date_gmt":"2019-10-06T19:21:19","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2579"},"modified":"2024-01-22T17:05:09","modified_gmt":"2024-01-22T16:05:09","slug":"nutrition-metabolism-and-gene-therapy","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/translational-medicine-area\/diabetes-and-metabolism-program\/nutrition-metabolism-and-gene-therapy\/","title":{"rendered":"Nutrition, metabolism and Gene Therapy"},"content":{"rendered":"\n<h1>\n\t\tNutrition, metabolism and Gene Therapy\n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\tThe group is focused on studying the metabolic implications of chronic diseases such as Obesity, Diabetes and Cancer. Using gene therapy, the group aims to modify the genome or genomic regulation of a patient using various strategies, in order to replace a shortage caused by a mutation, gene deregulation or malfunction of a cell-signalling pathway.<br \/>\nThrough this approach, this group studies cell metabolism, defining the mechanisms which the cells use to adapt to different conditions (stress due to lack of nutrients, physical effort, etc.), which it uses as a basis for proposing new strategies in the treatment of diseases such as diabetes and cancer, or in patients with liver damage or patients having undergone high-risk surgeries.\n<h2>390<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/srynge.jpg\" alt=\"srynge\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"srynge\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\t&#8211; Study of the role of PEPCK-M and mitochondrial physiology in cancer metabolism<br \/>\n&#8211; Metabolic plasticity in obesity and type-2 diabetes<br \/>\n&#8211; Application of genetics and stable isotope-based metabolomics approaches to investigate the metabolism of tumours in vivo, and to uncover metabolic targets for cancer treatment.<br \/>\n&#8211; Characterisation of the genomic and functional structure of the codifying pfkfb3 and pfkfb4 genes for the PFK2 enzyme (6-phosphofructo-2- kinase\/fructose 2,6-bisphosphatase).<br \/>\n&#8211; Study of the influence of different ergogenic aids on physical performance<br \/>\n&#8211; Evaluation of the influence of acute fat intake, prior to exercise, on the adaptation to effort and the performance in long-lasting efforts\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Gonzalez Franquesa A, Gama Perez P, Kulis M, Szczepanowska K, Dahdah N, Moreno Gomez S, Latorre Pellicer A, Fern\u00e1ndez Ruiz R, Aguilar Mogas A, Hoffman A, Monelli E, Samino S, Mir\u00f3 Blanch J, Oemer G, Duran X, Sanchez Rebordelo E, Schneeberger M, Obach M, Montane J, Castellano G, Chapaprieta V, Sun W, Navarro L, Prieto I, Casta\u00f1o C, Novials A, Gomis R, Monsalve M, Claret M, Graupera M, Soria G, Wolfrum C, Vendrell J, Fern\u00e1ndez Veledo S, Enr\u00edquez JA, Carracedo A, Perales JC, Nogueiras R, Herrero L, Trifunovic A, Keller MA, Yanes O, Sales Pardo M, Guimer\u00e0 R, Bl\u00fcher M, Mart\u00edn Subero JI, Garcia Roves PM. <strong>Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue<\/strong>. Redox Biol. 2022;54102353-102353. doi:10.1016\/j.redox.2022.102353.\n<p>Hyro\u0161\u0161ov\u00e1 P, Arag\u00f3 M, Mu\u00f1oz Pinedo C, Vi\u00f1als F, Garc\u00eda Rov\u00e9s PM, Escolano C, M\u00e9ndez Lucas A, Perales JC. <strong>Glycosylation defects, offset by PEPCK-M, drive entosis in breast carcinoma cells<\/strong>. Cell Death Dis. 2022;13(8):730-730. doi:10.1038\/s41419-022-05177-x.<\/p>\n<p>Nadeu F, Royo R, Massoni Badosa R, Playa Albinyana H, Garcia Torre B, Duran Ferrer M, Dawson KJ, Kulis M, Diaz Navarro A, Villamor N, Melero JL, Chapaprieta V, Dueso Barroso A, Delgado J, Moia R, Ruiz Gil S, Marchese D, Gir\u00f3 A, Verdaguer Dot N, Romo M, Clot G, Rozman M, Frigola G, Rivas Delgado A, Baumann T, Alcoceba M, Gonz\u00e1lez M, Climent F, Abrisqueta P, Castellv\u00ed J, Bosch F, Aymerich M, Enjuanes A, Ruiz Gasp\u00e0 S, L\u00f3pez Guillermo A, Jares P, Be\u00e0 S, Capella Gutierrez S, Gelp\u00ed JL, L\u00f3pez Bigas N, Torrents D, Campbell PJ, Gut I, Rossi D, Gaidano G, Puente XS, Garcia Roves PM, Colomer D, Heyn H, Maura F, Mart\u00edn Subero JI, Campo E. <strong>Detection of early seeding of Richter transformation in chronic lymphocytic leukemia<\/strong>. NAT MED. 2022;28(8):1662-1671. doi:10.1038\/s41591-022-01927-8.<\/p>\n<p>Monelli E, Villacampa P, Zabala Letona A, Martinez Romero A, Llena J, Beiroa D, Gouveia L, Chivite I, Zagmutt S, Gama Perez P, Osorio Conles O, Muixi L, Martinez Gonzalez A, Castillo SD, Mart\u00edn N, Castel P, Valcarcel Jimenez L, Garcia Gonzalez I, Villena JA, Fernandez Ruiz S, Serra D, Herrero L, Benedito R, Garcia Roves P, Vidal J, Cohen P, Nogueiras R, Claret M, Carracedo A, Graupera M. <strong>Angiocrine polyamine production regulates adiposity<\/strong>. Nat Metab. 2022;4(3):327-343. doi:10.1038\/s42255-022-00544-6.<\/p>\nHuber Ruano I, Calvo E, Mayneris Perxachs J, Rodr\u00edguez Pe\u00f1a MM, Ceperuelo Mallafr\u00e9 V, Ced\u00f3 L, N\u00fa\u00f1ez Roa C, Miro Blanch J, Arnoriaga Rodr\u00edguez M, Balvay A, Maudet C, Garc\u00eda Roves P, Yanes O, Rabot S, Grimaud GM, De Prisco A, Amoruso A, Fern\u00e1ndez Real JM, Vendrell J, Fern\u00e1ndez Veledo S. <strong>Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate<\/strong>. Microbiome. 2022;10(1):135-135. doi:10.1186\/s40168-022-01306-y.<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<h3>Estudio integrativo y traslacional de la desregulaci\u00f3n metab\u00f3lica debida a la obesidad. Repercusiones sobre la plasticidad del tejido adiposo blanco<\/h3>\n<p>Garcia-Roves Gonzalez, Pablo Miguel (Investigador principal (IP))<\/p>\n<p>Ref.: PI15\/00701<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>FIS-INSTITUTO DE SALUD CARLOS III<\/li>\n<\/ul>\n<p>2016-01-01 &#8211; 2018-12-31<\/p>\n<hr \/>\n<h3>ESTANCIA BREVE BECA FPI BES-2007-16437<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: EEBB-2011-44136<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2011-01-01 &#8211; 2011-12-31<\/p>\n<hr \/>\n<h3>Regulaci\u00f3n y funci\u00f3n de los genes pfkfb3,pfkfb4 y TIGAR<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: BUF2009-07380<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2010-01-01 &#8211; 2012-12-31<\/p>\n<hr \/>\n<h3>FPI &#8211; BES-2007-16437<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: FPI-BES-2007-16437<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2009-07-02 &#8211; 2011-07-01<\/p>\n<hr \/>\n<h3>Conv. Mutua Madrile\u00f1a &#8212; DR. JAVIERRE<\/h3>\n<p>Javierre Garces, Casimiro (Investigador principal (IP))<\/p>\n<p>Ref.: 07PRV009<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>FUNDACI\u00d3 MUTUA MADRILE\u00d1A<\/li>\n<\/ul>\n<p>2007-05-04 &#8211; 2010-05-03<\/p>\n<hr \/>\n<h3>BFU2006-02412<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: BFU2006-02412<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2007-01-01 &#8211; 2009-09-30<\/p>\n<hr \/>\n<h3>Inv. Efectes aspirina &#8212; Dr. Bartrons<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: 94VAR026<\/p>\n<hr \/>\n<h3>MTV3<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: MTV3<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MARATO TV3<\/li>\n<\/ul>\n<p>2006-01-01 &#8211; 2009-12-31<\/p>\n<hr \/>\n<h3>NOVES ESTRAT\u00c8GIES DE TERAPIA G\u00c8NICA PER AL TRACTAMENT DE LA MALALTIA INFLAMATORIA INTESTINAL: LA SILENCIACI\u00d3 DE L\u00b4EXPRESSI\u00d3 DE TNFalfa I LA SOBREEXPRESSI\u00d3 D\u00b4INTERLEUQUINA-10<\/h3>\n<p>Perales Losa, Jose Carlos (Investigador principal (IP))<\/p>\n<p>Ref.: 31633<\/p>\n<p>2006-01-01 &#8211; 2009-12-31<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Pablo-Garcia-Roves-Gonzalez-150x150.jpg\" alt=\"Pablo-Garcia-Roves-Gonzalez\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Pablo-Garcia-Roves-Gonzalez\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tGarcia-Roves Gonzalez, Pablo\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:pgarciaroves@idibell.cat\" title=\"pgarciaroves@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tpgarciaroves@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Pablo-Garcia-Roves-Gonzalez-150x150.jpg\" alt=\"Pablo-Garcia-Roves-Gonzalez\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Pablo-Garcia-Roves-Gonzalez\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tGarcia-Roves Gonzalez, Pablo\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:pgarciaroves@idibell.cat\" title=\"pgarciaroves@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tpgarciaroves@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Jose-Carlos-Perales-Losa.jpg\" alt=\"Jose-Carlos-Perales-Losa\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Jose-Carlos-Perales-Losa\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tPerales Losa, Jose Carlos\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:jperales@idibell.cat\" title=\"jperales@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tjperales@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/01\/Andres-Mendez-Lucas-150x150.jpg\" alt=\"Andres-Mendez-Lucas\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Andres-Mendez-Lucas\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMendez Lucas, Andres\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/06\/Anna-Manzano-Cuesta-150x150.jpg\" alt=\"Anna-Manzano-Cuesta\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Anna-Manzano-Cuesta\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tManzano Cuesta, Anna\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:amanzano@idibell.cat\" title=\"amanzano@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tamanzano@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tRELATED LINKS\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/m_roves\" title=\"@m_roves\" target=\"_blank\" rel=\"noopener\">\n\t\t@m_roves\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/Aml_Metab\" title=\"@Aml_Metab\" target=\"_blank\" rel=\"noopener\">\n\t\t@Aml_Metab\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPrincipal investigators \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tClinical researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-4\" data-index=\"4\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-4\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Garcia-Roves Gonzalez, Pablo<\/li>\n<\/ul>\n\t\t\t\t\t\tPrincipal investigators \n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Perales Losa, Jose Carlos<\/li>\n<li>Mendez Lucas, Andres<\/li>\n<li>Manzano Cuesta, Anna<\/li>\n<\/ul>\n\t\t\t\t\t\tClinical researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Javierre Garces, Casimiro<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Hyrossova, Petra<\/li>\n<li>Gama Perez, Pau<\/li>\n<li>Palmieri, Flavio<\/li>\n<\/ul>\n\t\t\t\t\t\tPredoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>De Benito Gomez, Lidia<\/li>\n<li>Tormo Fabios, Maria<\/li>\n<li>\u00a0Macias Hernanz, Manuel<\/li>\n<li>\u00a0\u00c1lvarez Luis, Jorge<\/li>\n<\/ul>\n<h2>\n\t\tNoticias relacionadas\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/23375\" content=\"Scientists create a mouse model to study the progression of a type of leukemia and look for more effective treatments\" \/><meta itemprop=\"datePublished\" content=\"2023-12-15\" \/><meta 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content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/07\/NO078-P-Garcia-Roves_Diabetes-Imatges.jpg\" \/><meta itemprop=\"width\" content=\"1280\" \/><meta itemprop=\"height\" content=\"720\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/07\/white-adipose-tissue-is-the-most-vulnerable-to-metabolic-changes-caused-by-obesity\/\" title=\"White adipose tissue is the most vulnerable to metabolic changes caused by obesity\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/07\/white-adipose-tissue-is-the-most-vulnerable-to-metabolic-changes-caused-by-obesity\/\" title=\"White adipose tissue is the most vulnerable to metabolic changes caused by obesity\">White adipose tissue is the most vulnerable to metabolic changes caused by obesity<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t20\/07\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/4904\" content=\"New results on the function of the tumor suppressor HERC protein\" \/><meta itemprop=\"datePublished\" content=\"2020-02-20\" \/><meta itemprop=\"dateModified\" content=\"2020-05-28\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/grup_1-1.jpg\" \/><meta itemprop=\"width\" content=\"840\" \/><meta itemprop=\"height\" content=\"450\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/02\/new-results-on-the-function-of-the-tumor-suppressor-herc-protein\/\" title=\"New results on the function of the tumor suppressor HERC protein\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/02\/new-results-on-the-function-of-the-tumor-suppressor-herc-protein\/\" title=\"New results on the function of the tumor suppressor HERC protein\">New results on the function of the tumor suppressor HERC protein<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t20\/02\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5307\" content=\"The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer\" \/><meta itemprop=\"datePublished\" content=\"2018-02-06\" \/><meta itemprop=\"dateModified\" content=\"2020-05-18\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/grup_isabel_fabregat_2016_2-1.jpg\" \/><meta itemprop=\"width\" content=\"640\" \/><meta itemprop=\"height\" content=\"480\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/02\/the-it-liver-european-consortium-expands-tgf-beta-knowledge-in-liver-cancer\/\" title=\"The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/02\/the-it-liver-european-consortium-expands-tgf-beta-knowledge-in-liver-cancer\/\" title=\"The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer\">The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t06\/02\/2018\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/6131\" content=\"Discovery of a mechanism that makes tumor cells sugar addicted\" \/><meta itemprop=\"datePublished\" content=\"2014-04-03\" \/><meta itemprop=\"dateModified\" content=\"2022-01-11\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/glucosa-1.jpg\" \/><meta itemprop=\"width\" content=\"1500\" \/><meta itemprop=\"height\" content=\"1020\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2014\/04\/discovery-of-a-mechanism-that-makes-tumor-cells-sugar-addicted\/\" title=\"Discovery of a mechanism that makes tumor cells sugar addicted\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2014\/04\/discovery-of-a-mechanism-that-makes-tumor-cells-sugar-addicted\/\" title=\"Discovery of a mechanism that makes tumor cells sugar addicted\">Discovery of a mechanism that makes tumor cells sugar addicted<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t03\/04\/2014\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/6468\" content=\"Licensed a patent to Janus Developments for the treatment of inflammatory diseases\" \/><meta itemprop=\"datePublished\" content=\"2013-01-28\" \/><meta itemprop=\"dateModified\" content=\"2022-03-01\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2013\/01\/Logo-Janus-1.jpg\" \/><meta itemprop=\"width\" content=\"768\" \/><meta itemprop=\"height\" content=\"280\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2013\/01\/licensed-a-patent-to-janus-developments-for-the-treatment-of-inflammatory-diseases\/\" title=\"Licensed a patent to Janus Developments for the treatment of inflammatory diseases\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2013\/01\/licensed-a-patent-to-janus-developments-for-the-treatment-of-inflammatory-diseases\/\" title=\"Licensed a patent to Janus Developments for the treatment of inflammatory diseases\">Licensed a patent to Janus Developments for the treatment of inflammatory diseases<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t28\/01\/2013\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Nutrition, metabolism and Gene Therapy Summary The group is focused on studying the metabolic implications of chronic diseases such as Obesity, Diabetes and Cancer. Using gene therapy, the group aims to modify the genome or genomic regulation of a patient using various strategies, in order to replace a shortage caused by a mutation, gene deregulation [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":540,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"publishpress_future_action":{"enabled":false,"date":"2024-05-10 07:05:44","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2579"}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=2579"}],"version-history":[{"count":5,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2579\/revisions"}],"predecessor-version":[{"id":23559,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2579\/revisions\/23559"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/540"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=2579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}