{"id":2579,"date":"2019-10-06T21:21:19","date_gmt":"2019-10-06T19:21:19","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=2579"},"modified":"2025-01-28T15:40:01","modified_gmt":"2025-01-28T14:40:01","slug":"nutrition-metabolism-and-gene-therapy","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/translational-medicine-area\/diabetes-and-metabolism-program\/nutrition-metabolism-and-gene-therapy\/","title":{"rendered":"Nutrition, metabolism and Gene Therapy"},"content":{"rendered":"\n<h1>\n\t\tNutrition, metabolism and gene therapy\n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\tThe group is focused on studying the metabolic implications of chronic diseases such as Obesity, Diabetes and Cancer. Using gene therapy, the group aims to modify the genome or genomic regulation of a patient using various strategies, in order to replace a shortage caused by a mutation, gene deregulation or malfunction of a cell-signalling pathway.<br \/>\nThrough this approach, this group studies cell metabolism, defining the mechanisms which the cells use to adapt to different conditions (stress due to lack of nutrients, physical effort, etc.), which it uses as a basis for proposing new strategies in the treatment of diseases such as diabetes and cancer, or in patients with liver damage or patients having undergone high-risk surgeries.\n<h2>390<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/srynge.jpg\" alt=\"srynge\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"srynge\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t&#8211; Study of the role of PEPCK-M and mitochondrial physiology in cancer metabolism<br \/>\n&#8211; Metabolic plasticity in obesity and type-2 diabetes<br \/>\n&#8211; Application of genetics and stable isotope-based metabolomics approaches to investigate the metabolism of tumours in vivo, and to uncover metabolic targets for cancer treatment.<br \/>\n&#8211; Characterisation of the genomic and functional structure of the codifying pfkfb3 and pfkfb4 genes for the PFK2 enzyme (6-phosphofructo-2- kinase\/fructose 2,6-bisphosphatase).<br \/>\n&#8211; Study of the influence of different ergogenic aids on physical performance<br \/>\n&#8211; Evaluation of the influence of acute fat intake, prior to exercise, on the adaptation to effort and the performance in long-lasting efforts\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Kreuzaler,P;Inglese,P;Ghanate,A;Gjelaj,E;Wu,VC;Panina,Y;Mendez Lucas,A et al, <strong>Vitamin B<sub>5<\/sub> supports MYC oncogenic metabolism and tumor progression in breast cancer<\/strong>, Nat. Metab., 2023;5(11):doi:10.1038\/s42255-023-00915-7<\/li>\n<li>Jansen,KM;Dahdah,N;Gama Perez,P;Schots,PC;Larsen,TS;Garcia Roves,PM, <strong>Impact of GLP-1 receptor agonist versus omega-3 fatty acids supplement on obesity-induced alterations of mitochondrial respiration<\/strong>, Front. Endocrinol., 2023;141098391-1098391, doi:10.3389\/fendo.2023.1098391<\/li>\n<li>Pimenta Lopes,C;S\u00e1nchez Diego,C;Deber,A;Egea Cort\u00e9s,A;Valer,JA;Alcal\u00e1,A;M\u00e9ndez Lucas,A et al, <strong>Inhibition of C5AR1 impairs osteoclast mobilization and prevents bone loss<\/strong>., Mol. Ther., 2023;31(8):2507-2523, doi:10.1016\/j.ymthe.2023.04.022<\/li>\n<li>Playa Albinyana,H;Arenas,F;Royo,R;Gir\u00f3,A;L\u00f3pez Oreja,I;Aymerich,M;L\u00f3pez Guerra,M et al, <strong>Chronic lymphocytic leukemia patient-derived xenografts recapitulate clonal evolution to Richter transformation<\/strong>., Leukemia, 2023;doi:10.1038\/s41375-023-02095-5<\/li>\n<li>Jansen,KM;Dahdah,N;Gama Perez,P;Schots,PC;Larsen,TS;Garcia Roves,PM, <strong>Impact of GLP-1 receptor agonist versus omega-3 fatty acids supplement on obesity-induced alterations of mitochondrial respiration<\/strong>, Front. Endocrinol., 2023;141098391-1098391, doi:10.3389\/fendo.2023.1098391<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<h3>Estudio integrativo y traslacional de la desregulaci\u00f3n metab\u00f3lica debida a la obesidad. Repercusiones sobre la plasticidad del tejido adiposo blanco<\/h3>\n<p>Garcia-Roves Gonzalez, Pablo Miguel (Investigador principal (IP))<\/p>\n<p>Ref.: PI15\/00701<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>FIS-INSTITUTO DE SALUD CARLOS III<\/li>\n<\/ul>\n<p>2016-01-01 &#8211; 2018-12-31<\/p>\n<hr \/>\n<h3>ESTANCIA BREVE BECA FPI BES-2007-16437<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: EEBB-2011-44136<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2011-01-01 &#8211; 2011-12-31<\/p>\n<hr \/>\n<h3>Regulaci\u00f3n y funci\u00f3n de los genes pfkfb3,pfkfb4 y TIGAR<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: BUF2009-07380<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2010-01-01 &#8211; 2012-12-31<\/p>\n<hr \/>\n<h3>FPI &#8211; BES-2007-16437<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: FPI-BES-2007-16437<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2009-07-02 &#8211; 2011-07-01<\/p>\n<hr \/>\n<h3>Conv. Mutua Madrile\u00f1a &#8212; DR. JAVIERRE<\/h3>\n<p>Javierre Garces, Casimiro (Investigador principal (IP))<\/p>\n<p>Ref.: 07PRV009<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>FUNDACI\u00d3 MUTUA MADRILE\u00d1A<\/li>\n<\/ul>\n<p>2007-05-04 &#8211; 2010-05-03<\/p>\n<hr \/>\n<h3>BFU2006-02412<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: BFU2006-02412<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MINISTERIO DE EDUCACI\u00d3N Y CIENCIA<\/li>\n<\/ul>\n<p>2007-01-01 &#8211; 2009-09-30<\/p>\n<hr \/>\n<h3>Inv. Efectes aspirina &#8212; Dr. Bartrons<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: 94VAR026<\/p>\n<hr \/>\n<h3>MTV3<\/h3>\n<p>Bartrons Bach, Ramon (Investigador principal (IP))<\/p>\n<p>Ref.: MTV3<\/p>\n<p>Entitat finan\u00e7adora:<\/p>\n<ul>\n<li>MARATO TV3<\/li>\n<\/ul>\n<p>2006-01-01 &#8211; 2009-12-31<\/p>\n<hr \/>\n<h3>NOVES ESTRAT\u00c8GIES DE TERAPIA G\u00c8NICA PER AL TRACTAMENT DE LA MALALTIA INFLAMATORIA INTESTINAL: LA SILENCIACI\u00d3 DE L\u00b4EXPRESSI\u00d3 DE TNFalfa I LA SOBREEXPRESSI\u00d3 D\u00b4INTERLEUQUINA-10<\/h3>\n<p>Perales Losa, Jose Carlos (Investigador principal (IP))<\/p>\n<p>Ref.: 31633<\/p>\n<p>2006-01-01 &#8211; 2009-12-31<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Pablo-Garcia-Roves-Gonzalez-150x150.jpg\" alt=\"Pablo-Garcia-Roves-Gonzalez\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Pablo-Garcia-Roves-Gonzalez\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tGarcia-Roves Gonzalez, Pablo\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:pgarciaroves@idibell.cat\" title=\"pgarciaroves@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\tpgarciaroves@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Pablo-Garcia-Roves-Gonzalez-150x150.jpg\" alt=\"Pablo-Garcia-Roves-Gonzalez\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Pablo-Garcia-Roves-Gonzalez\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tGarcia-Roves Gonzalez, Pablo\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:pgarciaroves@idibell.cat\" title=\"pgarciaroves@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\tpgarciaroves@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Jose-Carlos-Perales-Losa.jpg\" alt=\"Jose-Carlos-Perales-Losa\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Jose-Carlos-Perales-Losa\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tPerales Losa, Jose Carlos\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:jperales@idibell.cat\" title=\"jperales@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\tjperales@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/01\/Andres-Mendez-Lucas-150x150.jpg\" alt=\"Andres-Mendez-Lucas\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Andres-Mendez-Lucas\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMendez Lucas, Andres\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/06\/Anna-Manzano-Cuesta-150x150.jpg\" alt=\"Anna-Manzano-Cuesta\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Anna-Manzano-Cuesta\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tManzano Cuesta, Anna\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:amanzano@idibell.cat\" title=\"amanzano@idibell.cat\"  target=\"_blank\"  rel=\"noopener\">\n\t\tamanzano@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tRELATED LINKS\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/m_roves\" title=\"@m_roves\"  target=\"_blank\"  rel=\"noopener\">\n\t\t@m_roves\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/Aml_Metab\" title=\"@Aml_Metab\"  target=\"_blank\"  rel=\"noopener\">\n\t\t@Aml_Metab\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPrincipal investigators \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tClinical researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-4\" data-index=\"4\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-4\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Garcia-Roves Gonzalez, Pablo<\/li>\n<\/ul>\n\t\t\t\t\t\tPrincipal investigators \n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Perales Losa, Jose Carlos<\/li>\n<li>Mendez Lucas, Andres<\/li>\n<li>Manzano Cuesta, Anna<\/li>\n<\/ul>\n\t\t\t\t\t\tClinical researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Javierre Garces, Casimiro<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Hyrossova, Petra<\/li>\n<li>Gama Perez, Pau<\/li>\n<li>Palmieri, Flavio<\/li>\n<\/ul>\n\t\t\t\t\t\tPredoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>De Benito Gomez, Lidia<\/li>\n<li>Tormo Fabios, Maria<\/li>\n<li>\u00c1lvarez Luis, Jorge<\/li>\n<li>Barrientos Salinas, Roberto Gustavo<\/li>\n<\/ul>\n<h2>\n\t\tNoticias relacionadas\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/23375\" content=\"Scientists create a mouse model to study the progression of a type of leukemia and look for more effective treatments\" \/><meta itemprop=\"datePublished\" content=\"2023-12-15\" \/><meta 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itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/02\/new-results-on-the-function-of-the-tumor-suppressor-herc-protein\/\" title=\"New results on the function of the tumor suppressor HERC protein\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2020\/02\/new-results-on-the-function-of-the-tumor-suppressor-herc-protein\/\" title=\"New results on the function of the tumor suppressor HERC protein\">New results on the function of the tumor suppressor HERC protein<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t20\/02\/2020\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/5307\" content=\"The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer\" \/><meta itemprop=\"datePublished\" content=\"2018-02-06\" \/><meta itemprop=\"dateModified\" content=\"2020-05-18\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/grup_isabel_fabregat_2016_2-1.jpg\" \/><meta itemprop=\"width\" content=\"640\" \/><meta itemprop=\"height\" content=\"480\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/02\/the-it-liver-european-consortium-expands-tgf-beta-knowledge-in-liver-cancer\/\" title=\"The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2018\/02\/the-it-liver-european-consortium-expands-tgf-beta-knowledge-in-liver-cancer\/\" title=\"The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer\">The IT-LIVER European consortium expands TGF-beta knowledge in liver cancer<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t06\/02\/2018\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/6131\" content=\"Discovery of a mechanism that makes tumor cells sugar addicted\" \/><meta itemprop=\"datePublished\" content=\"2014-04-03\" \/><meta itemprop=\"dateModified\" content=\"2022-01-11\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" 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href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t03\/04\/2014\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/6468\" content=\"Licensed a patent to Janus Developments for the treatment of inflammatory diseases\" \/><meta itemprop=\"datePublished\" content=\"2013-01-28\" \/><meta itemprop=\"dateModified\" content=\"2022-03-01\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/erigin\/\" \/><meta itemprop=\"name\" content=\"Idibell\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2013\/01\/Logo-Janus-1.jpg\" \/><meta itemprop=\"width\" content=\"768\" \/><meta itemprop=\"height\" content=\"280\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2013\/01\/licensed-a-patent-to-janus-developments-for-the-treatment-of-inflammatory-diseases\/\" title=\"Licensed a patent to Janus Developments for the treatment of inflammatory diseases\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2013\/01\/licensed-a-patent-to-janus-developments-for-the-treatment-of-inflammatory-diseases\/\" title=\"Licensed a patent to Janus Developments for the treatment of inflammatory diseases\">Licensed a patent to Janus Developments for the treatment of inflammatory diseases<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/erigin\/\">Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t28\/01\/2013\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Nutrition, metabolism and gene therapy Summary The group is focused on studying the metabolic implications of chronic diseases such as Obesity, Diabetes and Cancer. Using gene therapy, the group aims to modify the genome or genomic regulation of a patient using various strategies, in order to replace a shortage caused by a mutation, gene deregulation [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":540,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-2579","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2025-04-10 22:07:51","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=2579"}],"version-history":[{"count":10,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2579\/revisions"}],"predecessor-version":[{"id":25253,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/2579\/revisions\/25253"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/540"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=2579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}