{"id":25056,"date":"2025-01-08T09:44:42","date_gmt":"2025-01-08T08:44:42","guid":{"rendered":"https:\/\/idibell.cat\/en\/?page_id=25056"},"modified":"2025-01-21T11:46:15","modified_gmt":"2025-01-21T10:46:15","slug":"gene-regulation-of-cell-identity","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/neuroscience-area\/neuroscience-program\/gene-regulation-of-cell-identity\/","title":{"rendered":"Gene regulation of cell identity"},"content":{"rendered":"\n

\n\t\tGene regulation of cell identity\n\t<\/h1>\n

\n\t\tSummary\n\t<\/h3>\n\t

The mechanisms that define cell identity in complex organisms are still largely unknown. Most efforts have been focused on understanding how a few transcription factors direct cell differentiation in particular circumstances, such as during development or in cancer. However, many post-transcriptional processes, which are essential for defining the final transcript repertoire in a cell, have been overlooked and their role in establishing this identity is much less understood. In the lab, we want to understand how post-transcriptional regulatory processes, and in particular alternative polyadenylation, are coordinated at the individual cell level and how they contribute to the differentiation of cells both in health and disease conditions.<\/p>\n

22<\/h2>\n

Publications<\/h2>\n\t\t\t\t\"Gene-Regulation-of-Cell-Identity\"\n\t\t\t\t\tStrategic Lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tFunctional analysis of alternative polyadenylation in cell differentiation
\nCharacterization of RNA metabolism defects in neurodegenerative diseases
\nStudy of RNA Binding Protein function in the definition of cell type identity\n\t\t\t\t\tSelected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t