{"id":24709,"date":"2024-10-29T16:26:14","date_gmt":"2024-10-29T15:26:14","guid":{"rendered":"https:\/\/idibell.cat\/en\/?page_id=24709"},"modified":"2024-12-13T11:24:01","modified_gmt":"2024-12-13T10:24:01","slug":"pancreas-regeneration-pancreatic-progenitors-and-their-niche","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/cancer-area\/molecular-mechanisms-and-experimental-therapy-in-oncology-program-oncobell\/pancreas-regeneration-pancreatic-progenitors-and-their-niche\/","title":{"rendered":"Pancreas regeneration: pancreatic progenitors and their niche"},"content":{"rendered":"\n<h1>\n\t\tPancreas regeneration: pancreatic progenitors and their niche\n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\t<p>Type 1 diabetes is caused by an autoimmune destruction of pancreatic \u03b2 cells. These cells are the source of insulin, a hormone required for the regulation of blood glucose levels. One approach to recovering glucose homeostasis would be to induce restoration of \u03b2-cell mass, either by replacement with exogenous cells or by regeneration from endogenous progenitors, but the existence of such progenitors is still controversial. Rovira&#8217;s group is focused in the role of ductal cells as pancreatic progenitors in order to develop new therapies for diabetes treatment. On the other hand the lab is also studying the niche required for pancreatic progenitor maintenance.<\/p>\n<h2>\n\t\t22\n\t<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/05\/Pancreas-regeneration-pancreatic-progenitors-and-their-niche.png\" alt=\"Pancreas-regeneration-pancreatic-progenitors-and-their-niche\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"Pancreas-regeneration-pancreatic-progenitors-and-their-niche\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<p>To develop therapies to maintain normoglicemia in diabetic patients to avoid or reduce T1D complications.<\/p>\n<p>To develop regenerative therapies in human diabetes, either through manipulation of pancreatic exocrine tissue from donors in vitro, and their subsequent transplantation, or through in vivo or in vitro manipulation of patients&#8217; pancreatic duct cells.<\/p>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Kovatcheva,M;Melendez,E;Chondronasiou,D;Pietrocola,F;Bernad,R;Caballe,A;Junza,A et al, <strong>Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair<\/strong>, Nat. Metab., 2023;5(11):1911-1930, doi:10.1038\/s42255-023-00916-6<\/li>\n<li>Villarroya Beltri,C;Martins,A;Garc\u00eda,A;Gim\u00e9nez,D;Zarzuela,E;Novo,M;Del \u00c1lamo,C et al, <strong>Mammalian CDC14 phosphatases control exit from stemness in pluripotent cells<\/strong>., Embo J., 2023;42(1):doi:10.15252\/embj.2022111251<\/li>\n<li>Casamitjana J, Espinet E, Rovira M. <strong>Pancreatic Organoids for Regenerative Medicine and Cancer Research<\/strong>. Front. Cell. Dev. Biol. 2022;10886153-886153. doi:10.3389\/fcell.2022.886153.<\/li>\n<li>Karampelias C, Watt K, Mattsson CL, Ruiz \u00c1F, Rezanejad H, Mi J, Liu X, Chu L, Locasale JW, Korbutt GS, Rovira M, Larsson O, Andersson O. <strong>MNK2 deficiency potentiates \u00df-cell regeneration via translational regulation<\/strong>. Nat Chem Biol. 2022;18(9):942-953. doi:10.1038\/s41589-022-01047-x.<\/li>\n<li>Pera J, Casta\u00f1o J, Casamitjana J, Giorgetti A, Romero Moya D. <strong>Generation of heterozygous SAMD9 CRISPR\/Cas9-edited iPSC line (ESi086-A-3), carrying p.I1567M mutation<\/strong>. Stem Cell Res. 2022;64102906-102906. doi:10.1016\/j.scr.2022.102906.<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"-1\"><i title=\"Expand\">Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>PSJ23052. <strong>THE CELL OF ORIGIN OF PANCREATIC CANCER: NOVEL OPPORTUNITIES FOR THE EARLY DIAGNOSIS AND TREATMENT. FUNDACI\u00d3N CRIS DE INVESTIGACI\u00d3N PARA VENCER EL C\u00c1NCER CRIS CONTRA EL C\u00c1NCER<\/strong>. Budget: 1.231.423,1\u20ac. 2023- . PI: Rovira Clusellas, Meritxell.<\/li>\n<li>LCX22021. <strong>The cell of origin of Pancreatic Cancer: novel opportunities for the early diagnosis and treatment (oriPDAC4diagTreat)<\/strong>. FUNDACI\u00d3 &#8220;LA CAIXA&#8221;. Budget: 323.980\u20ac. 2023-2026. PI: Rovira Clusellas, Meritxell.<\/li>\n<li>INT21020. <strong>Comprehensive characterization of human ductal epithelium to identify endogenous progenitors as beta cell source<\/strong>. EUROPEAN FOUNDATION FOR THE STUDY OF DIABETES (EFSD). Budget: 50.448\u20ac. 2022-2024. PI: Rovira Clusellas, Meritxell; Montanya Mias, Eduard.<\/li>\n<li>19PNJ139. <strong>C\u00e9lulas ductales pancre\u00e1ticas como fuente de c\u00e9lulas beta para el tratamiento de diabetes<\/strong>. l&#8217;oreal-UNESCO. 2019- . PI: Rovira Clusellas, Meritxell.<\/li>\n<li>DON23031. <strong>Organoids for diabetes treatment<\/strong>. Bon Preu. Budget: 25.907\u20ac. 2024-2025. PI: Rovira Clusellas, Meritxell.<\/li>\n<\/ul>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/10\/Meritxell-Rovira22-150x150.jpg\" alt=\"Meritxell-Rovira22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Meritxell-Rovira22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tRovira Clusellas, Meritxell\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:mrovira@idibell.cat\" title=\"mrovira@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tmrovira@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/10\/Meritxell-Rovira22-150x150.jpg\" alt=\"Meritxell-Rovira22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Meritxell-Rovira22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tRovira Clusellas, Meritxell\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:mrovira@idibell.cat\" title=\"mrovira@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tmrovira@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tRELATED LINKS\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/LabRovira\" title=\"@LabRovira\" target=\"_blank\" rel=\"noopener\">\n\t\t@LabRovira\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/orcid.org\/0000-0002-0538-4846\" title=\"ORCID\" target=\"_blank\" rel=\"noopener\">\n\t\tORCID\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/scholar.google.es\/citations?user=QQNwt64AAAAJ&#038;hl=en\" title=\"Google Scholar\" target=\"_blank\" rel=\"noopener\">\n\t\tGoogle Scholar\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tInvestigadors\/es predoctorals \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tScientific support\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Rovira Clusellas, Meritxell<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Casamitjana Vicente, Joan<\/li>\n<\/ul>\n\t\t\t\t\t\tInvestigadors\/es predoctorals \n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Fern\u00e1ndez Ruiz, \u00c1ngel<\/li>\n<li>Holguin Horcajo, Adrian<\/li>\n<\/ul>\n\t\t\t\t\t\tScientific support\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Moro Borrego, Joel<\/li>\n<\/ul>\n<h2>\n\t\tRelated news\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/24529\" content=\"Researchers describe a cellular map of the pancreas that will help design better treatments against pancreatic cancer and diabetes\" \/><meta itemprop=\"datePublished\" content=\"2024-09-02\" \/><meta itemprop=\"dateModified\" content=\"2024-09-02\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2024\/09\/MRovira-Gastroenterology-16-9-WEB-1.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/09\/researchers-describe-a-cellular-map-of-the-pancreas-that-will-help-design-better-treatments-against-pancreatic-cancer-and-diabetes\/\" title=\"Researchers describe a cellular map of the pancreas that will help design better treatments against pancreatic cancer and diabetes\"><\/a>\n\t\t\t\t<h6 itemprop=\"headline\">\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/09\/researchers-describe-a-cellular-map-of-the-pancreas-that-will-help-design-better-treatments-against-pancreatic-cancer-and-diabetes\/\" title=\"Researchers describe a cellular map of the pancreas that will help design better treatments against pancreatic cancer and diabetes\">Researchers describe a cellular map of the pancreas that 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IDIBELL\" \/><meta itemprop=\"datePublished\" content=\"2023-11-07\" \/><meta itemprop=\"dateModified\" content=\"2023-11-07\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2023\/11\/Captura-de-pantalla-2023-11-07-a-les-9.41.50.png\" \/><meta itemprop=\"width\" content=\"1076\" \/><meta itemprop=\"height\" content=\"667\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/11\/bonpreu-and-esclat-join-the-fight-against-diabetes-with-a-fundraising-campaign-in-favor-of-idibell\/\" title=\"Bonpreu and Esclat join the fight against diabetes with a fundraising campaign in favor of IDIBELL\"><\/a>\n\t\t\t\t<h6 itemprop=\"headline\">\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/11\/bonpreu-and-esclat-join-the-fight-against-diabetes-with-a-fundraising-campaign-in-favor-of-idibell\/\" title=\"Bonpreu and Esclat join the fight against diabetes with a fundraising campaign in favor of IDIBELL\">Bonpreu and Esclat join the fight against diabetes with a fundraising campaign in favor of IDIBELL<\/a>\n\t\t<\/h6>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t07\/11\/2023\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/20886\" content=\"A study describes a new way to generate insulin-producing cells\" \/><meta itemprop=\"datePublished\" content=\"2022-06-22\" \/><meta itemprop=\"dateModified\" content=\"2022-06-21\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/06\/NO066-M-Rovira_Nature-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/06\/a-study-describes-a-new-way-to-generate-insulin-producing-cells\/\" title=\"A study describes a new way to generate insulin-producing cells\"><\/a>\n\t\t\t\t<h6 itemprop=\"headline\">\n\t\t\t<a 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href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t06\/05\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/19339\" content=\"We close a 2021 full of science!\" \/><meta itemprop=\"datePublished\" content=\"2021-12-30\" \/><meta itemprop=\"dateModified\" content=\"2021-12-23\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/NO123-Best-2021-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/12\/we-close-a-2021-full-of-science\/\" title=\"We close a 2021 full of science!\"><\/a>\n\t\t\t\t<h6 itemprop=\"headline\">\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/12\/we-close-a-2021-full-of-science\/\" title=\"We close a 2021 full of science!\">We close a 2021 full of science!<\/a>\n\t\t<\/h6>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t30\/12\/2021\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/18133\" content=\"Pancreatic beta-cell boost in mice paves way for future diabetes treatments\" \/><meta itemprop=\"datePublished\" content=\"2021-08-11\" \/><meta itemprop=\"dateModified\" content=\"2021-08-12\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/08\/NP29-Rovira_CRG-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/08\/pancreatic-beta-cell-boost-in-mice-paves-way-for-future-diabetes-treatments\/\" title=\"Pancreatic beta-cell boost in mice paves way for future diabetes treatments\"><\/a>\n\t\t\t\t<h6 itemprop=\"headline\">\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/08\/pancreatic-beta-cell-boost-in-mice-paves-way-for-future-diabetes-treatments\/\" title=\"Pancreatic beta-cell boost in mice paves way for future diabetes treatments\">Pancreatic beta-cell boost in mice paves way for future diabetes treatments<\/a>\n\t\t<\/h6>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t11\/08\/2021\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Pancreas regeneration: pancreatic progenitors and their niche Summary Type 1 diabetes is caused by an autoimmune destruction of pancreatic \u03b2 cells. These cells are the source of insulin, a hormone required for the regulation of blood glucose levels. One approach to recovering glucose homeostasis would be to induce restoration of \u03b2-cell mass, either by replacement [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":448,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"unboxed","site-sidebar-style":"unboxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-24709","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2025-03-01 15:37:05","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/24709","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=24709"}],"version-history":[{"count":7,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/24709\/revisions"}],"predecessor-version":[{"id":24968,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/24709\/revisions\/24968"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/448"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=24709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}