Publications<\/h2>\n\t\t\t\t![\"119-neurooncologia-jbruna-def\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/119-neurooncologia-jbruna-def.jpg\" "\\"119-neurooncologia-jbruna-def\\"")
\n\t\t\t\t\tStrategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tAssessment of new drugs and new treatment approaches for gliomas and meningiomas (Jordi Bruna, Carles Mesia, Ana Lucas, Carles Maj\u00f3s, Gerard Plans)
\nChemotherapy-induced peripheral neuropathies (Jordi Bruna, Roser Velasco)
\nCancer and cognition (Marta Sim\u00f3)
\nLeptomeningeal metastases (Jordi Bruna)
\nSurvival prognostic factors involved in central nervous system tumours (Noem\u00ed Vidal, Jordi Bruna, Carles Maj\u00f3s. Albert Pons)
\nPrevention and personalised treatment of brain metastases: development of new therapies based on the prevention and prognosis of biomarkers (Carles Mesia, Noem\u00ed Vidal, Gerard Plans, Ana Lucas)
\nQuantitative assessment of advanced MR techniques in clinical neurooncology (Carles Majos, Albert Pons)\n\t\t\t\t\tSelected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tCalls A, Torres Espin A, Tormo M, Martinez Escardo L, Bonet N, Casals F, Navarro X, Yuste VJ, Udina E, Bruna J. A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice<\/strong>. Ann. Clin. Transl. Neurol. 2022;9(12):1985-1998. doi:10.1002\/acn3.51691.<\/p>\nPons Escoda A, Garcia Ruiz A, Naval Baudin P, Grussu F, Fernandez JJS, Simo AC, Sarro NV, Fernandez Coello A, Bruna J, Cos M, Perez Lopez R, Majos C. Voxel-level analysis of normalized DSC-PWI time-intensity curves: a potential generalizable approach and its proof of concept in discriminating glioblastoma and metastasis<\/strong>. Eur Radiol. 2022;32(6):3705-3715. doi:10.1007\/s00330-021-08498-1.<\/p>\nPreusser M, Silvani A, Le Rhun E, Soffietti R, Lombardi G, Sepulveda JM, Brandal P, Brazil L, Bonneville Levard A, Lorgis V, Vauleon E, Bromberg J, Erridge S, Cameron A, Lefranc F, Clement PM, Dumont S, Sanson M, Bronnimann C, Balan\u00e1 C, Thon N, Lewis J, Mair MJ, Sievers P, Furtner J, Pichler J, Bruna J, Ducray F, Reijneveld JC, Mawrin C, Bendszus M, Marosi C, Golfinopoulos V, Coens C, Gorlia T, Weller M, Sahm F, Wick W. Trabectedin for recurrent WHO grade 2 or 3 meningioma: a randomized phase 2 study of the EORTC Brain Tumor Group (EORTC-1320-BTG)<\/strong>. Neuro-Oncology. 2022;24(5):755-767. doi:10.1093\/neuonc\/noab243.<\/p>\nKarteri S, Bruna J, Argyriou AA, Mariotto S, Velasco R, Alemany M, Kalofonou F, Alberti P, Dinoto A, Velissaris D, Stradella A, Cavaletti G, Ferrari S, Kalofonos HP. Prospectively Assessing Serum Neurofilament Light Chain Levels As A Biomarker Of Paclitaxel-Induced Peripheral Neurotoxicity In Breast Cancer Patients<\/strong>. J. Peripher. Nerv. Syst. 2022;27(2):166-174. doi:10.1111\/jns.12493.<\/p>\nMao X, Wu S, Calero P\u00e9rez P, Candiota AP, Alfonso P, Bruna J, Yuste VJ, Lorenzo J, Novio F, Ruiz Molina D. Synthesis and Validation of a Bioinspired Catechol-Functionalized Pt(IV) Prodrug for Preclinical Intranasal Glioblastoma Treatment<\/strong>. Cancers. 2022;14(2):doi:10.3390\/cancers14020410.<\/p>\n\t\t\t\t\tSelected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tFIS21056. Comprensi\u00f3n y modulaci\u00f3n de los mecanismos de respuesta senescente en la neuropat\u00eda inducida por platinos<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 172957,4. 2022-2024. PI: Bruna Escuer, Jordi.<\/p>\n21FIS037. Valoraci\u00f3n pron\u00f3stica de los gliomas cerebrales mediante espectroscopia por RMI (MRS-PROG)<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 58080. 2021-2023. PI: Majos Torro, Carles.<\/p>\n21FIS039. Neurotoxicidad inducida por quimioterapia y estado nutricional: biomarcadores cl\u00ednicos, s\u00e9ricos, radiol\u00f3gicos y neurofisiol\u00f3gicos asociados al desarrollo y la regeneraci\u00f3n nerviosa<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 93170. 2021-2023. PI: Velasco Fargas, Roser.<\/p>\n19FIS035. C\u00e1ncer de pulm\u00f3n y toxicidad cognitiva: marcadores serol\u00f3gicos y de neuroimagen de disrupci\u00f3n de la barrera hemato-encef\u00e1lica<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 93170. 2019-2023. PI: Sim\u00f3 Parra, Marta.<\/p>\n18ACL042. FASE III MULTIC\u00c9NTRICA, RANDOMIZADA DEL ESTUDIO PARA RADIOTERAPIA INTRAOPERATIVA EN CASO DE GLIOBLASTOMA MULTIFORME DE DIAGN\u00d3STICO NUEVO<\/strong>. Budget: 2000. 2018-2022. PI: Lucas Calduch, Anna.<\/p>\n\t\t\t\t\tMore Information<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tIdentification of markers of clinical and neurophysiological predictive risk for developing oxaliplatin-induced neuropathy.
\nNew demonstrations on the efficacy of the new sigma-1 receptor antagonist in preventing acute oxaliplatin-induced neuropathy in a randomised, phase 2 study.
\nDocumentation of longitudinal brain changes associated with prophylactic cranial irradiation and chemotherapy in patients with small-cell lung cancer.
\nIdentification of a common feature in glioblastomas: intrinsic deficiency of the DFF40\/CAD endonuclease which affects DNA hydrolysis during caspase-dependent cell death.\n\t\t\t\t![\"Jordi-Bruna22\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/10\/Jordi-Bruna22-150x150.jpg\" "\\"Jordi-Bruna22\\"")
\n\n\t\tBruna Escuer, Jordi\n\t<\/h4>\n\n\t\t\n\t\tjbruna@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t\n\n\t\tBruna Escuer, Jordi\n\t<\/h4>\n\n\t\t\n\t\tjbruna@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t![\"Marta-Simo\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/02\/Marta-Simo-150x150.jpg\" "\\"Marta-Simo\\"")
\n\n\t\tSimo Parra, Marta\n\t<\/h4>\n\n\t\t\n\t\tmsimo@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t![\"Carlos-Mesia-Barroso\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Carlos-Mesia-Barroso-150x150.jpg\" "\\"Carlos-Mesia-Barroso\\"")
\n\n\t\tMesia Barroso, Carlos\n\t<\/h4>\n\n\t\t\n\t\tcmesia@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t![\"Anna-Lucas-Calduch\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/05\/Anna-Lucas-Calduch-150x150.jpg\" "\\"Anna-Lucas-Calduch\\"")
\n\n\t\tLucas Calduch, Anna Maria\n\t<\/h4>\n\n\t\t\n\t\talucas@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t![\"Roser-Velasco-Fargas\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/11\/Roser-Velasco-Fargas-150x150.jpg\" "\\"Roser-Velasco-Fargas\\"")
\n\n\t\tVelasco Fargas, Roser\n\t<\/h4>\n\n\t\t\n\t\trvelasco@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t![\"Carles-Majos-Torro\"](\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/05\/Carles-Majos-Torro-150x150.jpg\" "\\"Carles-Majos-Torro\\"")
\n\n\t\tMajos Torro, Carlos\n\t<\/h4>\n\n\t\t\n\t\tcmajos@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\n\t\tRELATED LINKS\n\t<\/h4>\n\n\t\t\n\t\t@VelascoRoser\n\t\t<\/a>\n\t<\/h4>\n\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\tGroup leaders \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tPrincipal investigators\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tClinical researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tManagement support\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders \n\t\t\t\t\t\t\t\t\t\t\t\n- Bruna Escuer, Jordi<\/li>\n<\/ul>\n\t\t\t\t\t\tPrincipal investigators\n\t\t\t\t\t\t\t\t\t\t\t
\n- Velasco Fargas, Roser<\/li>\n
- Mesia Barroso, Carlos<\/li>\n
- Simo Parra, Marta<\/li>\n
- Majos Torro, Carlos<\/li>\n
- Lucas Calduch, Anna Maria<\/li>\n<\/ul>\n\t\t\t\t\t\tClinical researchers\n\t\t\t\t\t\t\t\t\t\t\t
\n- Fern\u00e1ndez Coello, Alejandro<\/li>\n
- Vidal Sarro, Noemi<\/li>\n
- Plans Ahicart, Gerard<\/li>\n
- Pons Escoda, Albert<\/li>\n<\/ul>\n\t\t\t\t\t\tPredoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t
\n- Alemany\u00a0 Mart\u00ed, Montserrat<\/li>\n
- Septien Rivera, Sara<\/li>\n<\/ul>\n\t\t\t\t\t\tManagement support\n\t\t\t\t\t\t\t\t\t\t\t
\n- Sala Corominas, Ros\u00f3<\/li>\n<\/ul>\n
\n\t\tRelated news\n\t<\/h2>\n\t\t\n\t\t\t\t<\/a>\n\t\t\tA new tool based on Artificial Intelligence will improve brain tumour diagnosis<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t12\/03\/2024\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tFirst clinical trial of a treatment that attacks lung cancer and brain metastasis at the same time<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t22\/08\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tThe diagnosis and treatment of glioblastoma during the 2008 financial crisis and the COVID-19 pandemic<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t17\/02\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tThe activation of a key protein completes the process of death by apoptosis in glioblastoma cells<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t24\/11\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tExercise prevents neuronal damage caused by lung cancer treatment<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t03\/06\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tResearchers define the clinical characteristics of the cerebral complications caused by oncological immunotherapies that determine the evolution<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t30\/03\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tIdentified the cellular process by which Cisplatin chemotherapy causes neuronal damage<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t29\/09\/2020\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tOligodendroglial brain tumor survivors run the risk of developing long-term cognitive impairment<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t09\/10\/2019\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tThe 4th edition of the charity sports day Sosciathlon collects \u20ac 18,000 for IDIBELL research<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t07\/11\/2018\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tResearchers prove the effectiveness of a new drug to prevent the onset and the pain of chemotherapy-induced neuropathy<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t23\/10\/2017\t\t\t\t\t\t\t\n\t\t\n\n","protected":false},"excerpt":{"rendered":"Neuro-Oncology Unit Summary The Neuro-Oncology group is focused in the study of brain tumor treatments and the neurological complications related with cancer and cancer treatments. The group’s aim is to create and reinforce a research network between clinical and preclinical researchers, both within and outside the institution, to provide novel therapeutic options for the patients, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":448,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"publishpress_future_action":{"enabled":false,"date":"2024-05-09 20:15:37","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1916"}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=1916"}],"version-history":[{"count":6,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1916\/revisions"}],"predecessor-version":[{"id":23903,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1916\/revisions\/23903"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/448"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=1916"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Pons Escoda A, Garcia Ruiz A, Naval Baudin P, Grussu F, Fernandez JJS, Simo AC, Sarro NV, Fernandez Coello A, Bruna J, Cos M, Perez Lopez R, Majos C. Voxel-level analysis of normalized DSC-PWI time-intensity curves: a potential generalizable approach and its proof of concept in discriminating glioblastoma and metastasis<\/strong>. Eur Radiol. 2022;32(6):3705-3715. doi:10.1007\/s00330-021-08498-1.<\/p>\n Preusser M, Silvani A, Le Rhun E, Soffietti R, Lombardi G, Sepulveda JM, Brandal P, Brazil L, Bonneville Levard A, Lorgis V, Vauleon E, Bromberg J, Erridge S, Cameron A, Lefranc F, Clement PM, Dumont S, Sanson M, Bronnimann C, Balan\u00e1 C, Thon N, Lewis J, Mair MJ, Sievers P, Furtner J, Pichler J, Bruna J, Ducray F, Reijneveld JC, Mawrin C, Bendszus M, Marosi C, Golfinopoulos V, Coens C, Gorlia T, Weller M, Sahm F, Wick W. Trabectedin for recurrent WHO grade 2 or 3 meningioma: a randomized phase 2 study of the EORTC Brain Tumor Group (EORTC-1320-BTG)<\/strong>. Neuro-Oncology. 2022;24(5):755-767. doi:10.1093\/neuonc\/noab243.<\/p>\n Karteri S, Bruna J, Argyriou AA, Mariotto S, Velasco R, Alemany M, Kalofonou F, Alberti P, Dinoto A, Velissaris D, Stradella A, Cavaletti G, Ferrari S, Kalofonos HP. Prospectively Assessing Serum Neurofilament Light Chain Levels As A Biomarker Of Paclitaxel-Induced Peripheral Neurotoxicity In Breast Cancer Patients<\/strong>. J. Peripher. Nerv. Syst. 2022;27(2):166-174. doi:10.1111\/jns.12493.<\/p>\n Mao X, Wu S, Calero P\u00e9rez P, Candiota AP, Alfonso P, Bruna J, Yuste VJ, Lorenzo J, Novio F, Ruiz Molina D. Synthesis and Validation of a Bioinspired Catechol-Functionalized Pt(IV) Prodrug for Preclinical Intranasal Glioblastoma Treatment<\/strong>. Cancers. 2022;14(2):doi:10.3390\/cancers14020410.<\/p>\n\t\t\t\t\tSelected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\t FIS21056. Comprensi\u00f3n y modulaci\u00f3n de los mecanismos de respuesta senescente en la neuropat\u00eda inducida por platinos<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 172957,4. 2022-2024. PI: Bruna Escuer, Jordi.<\/p>\n 21FIS037. Valoraci\u00f3n pron\u00f3stica de los gliomas cerebrales mediante espectroscopia por RMI (MRS-PROG)<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 58080. 2021-2023. PI: Majos Torro, Carles.<\/p>\n 21FIS039. Neurotoxicidad inducida por quimioterapia y estado nutricional: biomarcadores cl\u00ednicos, s\u00e9ricos, radiol\u00f3gicos y neurofisiol\u00f3gicos asociados al desarrollo y la regeneraci\u00f3n nerviosa<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 93170. 2021-2023. PI: Velasco Fargas, Roser.<\/p>\n 19FIS035. C\u00e1ncer de pulm\u00f3n y toxicidad cognitiva: marcadores serol\u00f3gicos y de neuroimagen de disrupci\u00f3n de la barrera hemato-encef\u00e1lica<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 93170. 2019-2023. PI: Sim\u00f3 Parra, Marta.<\/p>\n 18ACL042. FASE III MULTIC\u00c9NTRICA, RANDOMIZADA DEL ESTUDIO PARA RADIOTERAPIA INTRAOPERATIVA EN CASO DE GLIOBLASTOMA MULTIFORME DE DIAGN\u00d3STICO NUEVO<\/strong>. Budget: 2000. 2018-2022. PI: Lucas Calduch, Anna.<\/p>\n\t\t\t\t\tMore Information<\/a>\n\t\t\t\t\t\t\t\t\t\t\tExpand<\/i><\/a>\n\t\t\t\t\tIdentification of markers of clinical and neurophysiological predictive risk for developing oxaliplatin-induced neuropathy. Neuro-Oncology Unit Summary The Neuro-Oncology group is focused in the study of brain tumor treatments and the neurological complications related with cancer and cancer treatments. The group’s aim is to create and reinforce a research network between clinical and preclinical researchers, both within and outside the institution, to provide novel therapeutic options for the patients, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":448,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"publishpress_future_action":{"enabled":false,"date":"2024-05-09 20:15:37","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1916"}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=1916"}],"version-history":[{"count":6,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1916\/revisions"}],"predecessor-version":[{"id":23903,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1916\/revisions\/23903"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/448"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=1916"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nNew demonstrations on the efficacy of the new sigma-1 receptor antagonist in preventing acute oxaliplatin-induced neuropathy in a randomised, phase 2 study.
\nDocumentation of longitudinal brain changes associated with prophylactic cranial irradiation and chemotherapy in patients with small-cell lung cancer.
\nIdentification of a common feature in glioblastomas: intrinsic deficiency of the DFF40\/CAD endonuclease which affects DNA hydrolysis during caspase-dependent cell death.\n\t\t\t\t\n\n\t\tBruna Escuer, Jordi\n\t<\/h4>\n
\n\t\t\n\t\tjbruna@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t
\n\n\t\tBruna Escuer, Jordi\n\t<\/h4>\n
\n\t\t\n\t\tjbruna@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t
\n\n\t\tSimo Parra, Marta\n\t<\/h4>\n
\n\t\t\n\t\tmsimo@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t
\n\n\t\tMesia Barroso, Carlos\n\t<\/h4>\n
\n\t\t\n\t\tcmesia@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t
\n\n\t\tLucas Calduch, Anna Maria\n\t<\/h4>\n
\n\t\t\n\t\talucas@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t
\n\n\t\tVelasco Fargas, Roser\n\t<\/h4>\n
\n\t\t\n\t\trvelasco@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t
\n\n\t\tMajos Torro, Carlos\n\t<\/h4>\n
\n\t\t\n\t\tcmajos@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tRELATED LINKS\n\t<\/h4>\n
\n\t\t\n\t\t@VelascoRoser\n\t\t<\/a>\n\t<\/h4>\n
\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\tGroup leaders \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tPrincipal investigators\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tClinical researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\tManagement support\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders \n\t\t\t\t\t\t\t\t\t\t\t
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\n\t\tRelated news\n\t<\/h2>\n\t\t\n\t\t\t\t<\/a>\n\t\t\tA new tool based on Artificial Intelligence will improve brain tumour diagnosis<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t12\/03\/2024\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tFirst clinical trial of a treatment that attacks lung cancer and brain metastasis at the same time<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t22\/08\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tThe diagnosis and treatment of glioblastoma during the 2008 financial crisis and the COVID-19 pandemic<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t17\/02\/2023\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tThe activation of a key protein completes the process of death by apoptosis in glioblastoma cells<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t24\/11\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tExercise prevents neuronal damage caused by lung cancer treatment<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t03\/06\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tResearchers define the clinical characteristics of the cerebral complications caused by oncological immunotherapies that determine the evolution<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t30\/03\/2021\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tIdentified the cellular process by which Cisplatin chemotherapy causes neuronal damage<\/a>\n\t\t\tBy comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t29\/09\/2020\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tOligodendroglial brain tumor survivors run the risk of developing long-term cognitive impairment<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t09\/10\/2019\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tThe 4th edition of the charity sports day Sosciathlon collects \u20ac 18,000 for IDIBELL research<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t07\/11\/2018\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t<\/a>\n\t\t\tResearchers prove the effectiveness of a new drug to prevent the onset and the pain of chemotherapy-induced neuropathy<\/a>\n\t\t\tBy Idibell<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t | \n\t\t\t\t\t\t\t\t\t23\/10\/2017\t\t\t\t\t\t\t\n\t\t\n\n","protected":false},"excerpt":{"rendered":"