{"id":1732,"date":"2019-09-17T20:05:57","date_gmt":"2019-09-17T18:05:57","guid":{"rendered":"https:\/\/idibell.cat\/?page_id=1732"},"modified":"2024-09-19T14:07:06","modified_gmt":"2024-09-19T12:07:06","slug":"prett-2","status":"publish","type":"page","link":"https:\/\/idibell.cat\/en\/research\/cancer-area\/molecular-mechanisms-and-experimental-therapy-in-oncology-program-oncobell\/prett-2\/","title":{"rendered":"Preclinical and experimental research in thoracic tumors (PReTT)"},"content":{"rendered":"\n<h1>\n\t\tPreclinical and experimental research in thoracic tumors (PReTT)\n\t<\/h1>\n<h3>\n\t\tSummary\n\t<\/h3>\n\t<p>The PReTT group focuses on the study of novel therapeutic strategies in thoracic tumours combining basic molecular and patient-oriented translational research, bioinformatics, and also design and development of investigator-initiated clinical trials. In terms of basic research, we study the mechanisms through which tumour cells die in response to different treatments and stimuli. Analysing the responses both at cell and tumour microenvironment level, including the immune system and metabolic status. On the translational side, our focus is the validation of diagnostic and treatment response biomarkers in order to improve the clinical management of thoracic tumours. At the bioinformatics level, the aim is to improve the stratification of thoracic tumours and the identification of potentially novel treatments tailored to the molecular characteristics of the patient.<\/p>\n<h2>77<\/h2>\n<h2>Publications<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2020\/04\/108-mortcelular-cmunozpinedo-def.jpg\" alt=\"108-mortcelular-cmunozpinedo-def\" itemprop=\"image\" height=\"300\" width=\"600\" title=\"108-mortcelular-cmunozpinedo-def\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">Strategic lines<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\t\u2022 Characterisation of immune-tumour-stroma connections in thoracic tumours to improve therapeutic approaches (Ernest Nadal, Cristina Mu\u00f1oz-Pinedo and Xavier Sol\u00e9)<br \/>\n\u2022 Metabolic vulnerabilities of lung cancer and malignant pleural mesothelioma (Cristina Mu\u00f1oz-Pinedo and Ernest Nadal)<br \/>\n\u2022 Molecular mechanisms of apoptosis and other forms of cell death induced by metabolic challenges and ischaemia (Cristina Mu\u00f1oz-Pinedo)<br \/>\n\u2022 Study of germline and somatic genomic alterations in thoracic tumours in tumour tissue and liquid biopsy (Ernest Nadal and Xavier Sol\u00e9)<br \/>\n\u2022 Design and development of clinical trials with a solid scientific rationale (Ernest Nadal)<br \/>\n\u2022 Stratification of thoracic tumours based on the computational integration of omic data (Xavier Sol\u00e9 and Ernest Nadal)<br \/>\n\u2022 Identification of personalized treatments by integrating large-scale pharmacogenomics data and validated drug-response signatures (Xavier Sol\u00e9)\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\">Selected Publications<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-1\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>Nadal,E;Rodr\u00edguez Abreu,D;Sim\u00f3,M;Massut\u00ed,B;Juan,O;Huidobro,G;L\u00f3pez,R et al, <strong>Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer With Untreated Brain Metastases<\/strong> (Atezo-Brain, GECP17\/05), J. Clin. Oncol., 2023;41(28):4478-4485, doi:10.1200\/JCO.22.02561<\/li>\n<li>Hijazo Pechero,S;Alay,A;Cordero,D;Marin,R;Vilari\u00f1o,N;Palmero,R;Brenes,J et al, <strong>Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications<\/strong>, Mol. Oncol., 2023;18(2):453-470, doi:10.1002\/1878-0261.13550<\/li>\n<li>Favaro,F;Both,D;Derks,I;Spaargaren,M;Munoz Pinedo,C;Eldering,E, <strong>Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies<\/strong>, Oncogenesis, 2023;12(1):6-6, doi:10.1038\/s41389-023-00450-w<\/li>\n<li>Provencio,M;Nadal,E;Gonz\u00e1lez Larriba,JL;Mart\u00ednez Mart\u00ed,A;Bernab\u00e9,R;Bosch Barrera,J;Casal Rubio,J et al, <strong>Perioperative Nivolumab and Chemotherapy in Stage III Non-Small-Cell Lung Cancer<\/strong>, N. Engl. J. Med., 2023;389(6):doi:10.1056\/NEJMoa2215530<\/li>\n<li>Cho,BC;Lee,JS;Wu,YL;Cicin,I;Dols,MC;Ahn,MJ;Cuppens,K et al, <strong>Bintrafusp Alfa Versus Pembrolizumab in Patients With Treatment-Naive, Programmed Death-Ligand 1-High Advanced NSCLC: A Randomized, Open-Label, Phase 3 Trial<\/strong>, J. Thorac. Oncol., 2023;18(12):1731-1742, doi:10.1016\/j.jtho.2023.08.018<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\">Selected Projects<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-2\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>MCI22017. <strong>Estr\u00e9s metab\u00f3lico en c\u00e1ncer: la respuesta integrada al estr\u00e9s como diana terap\u00e9utica en c\u00e1ncer de pulm\u00f3n de c\u00e9lula no peque\u00f1a (APOMETALUNG2)<\/strong>. Ministerio de Ciencia e Innovaci\u00f3n. Budget: 312.500\u20ac. 2023-2026. PI: MU\u00d1OZ PINEDO, CRISTINA.<\/li>\n<li>FIS21087. <strong>Nuevas estrategias terap\u00e9uticas en mesotelioma pleural maligno basadas en inmunoterapia y terapias dirigidas a ciclo celular y senescencia celular<\/strong>. Instituto de Salud Carlos III (ISCIII). Budget: 195.415\u20ac. 2022-2024. PI: Nadal Alforja, Ernesto Samuel.<\/li>\n<li>20MAR002. <strong>Modulating glycemia to improve benefit of chemoradiotherapy and immunotherapy in Non-Small Cell Lung Carcinoma<\/strong>. Fundaci\u00f3 La Marat\u00f3 de TV3. Budget: 200.000\u20ac. 2020-2024. PI: MU\u00d1OZ PINEDO, CRISTINA.<\/li>\n<li>2022-158-1. <strong>A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Bemarituzumab Monotherapy and Combination with Docetaxel in Subjects with Squamous-Cell Non-Small-Cell Lung Cancer (FORTITUDE-201)<\/strong>. Amgen, S.A. Budget: 463.068\u20ac. 2022- . PI: Nadal Alforja, Ernesto Samuel.<\/li>\n<li>20ACL245. <strong>ESTUDIO DE FASE III, MULTIC\u00c9NTRICO, ALEATORIZADO, ABIERTO Y CONTROLADO PARA EVALUAR LA EFICACIA, LA SEGURIDAD Y LA FARMACOCIN\u00c9TICA DE ATEZOLIZUMAB EN COMBINACI\u00d3N CON CABOZANTINIB EN COMPARACI\u00d3N CON DOCETAXEL EN MONOTERAPIA EN PACIENTES CON C\u00c1NCER DE PULM\u00d3N NO MICROC\u00cdTICO TRATADO PREVIAMENTE CON UN ANTICUERPO ANTI-PD-L1\/PD-1 Y QUIMIOTERAPIA CON PLATINO<\/strong>. Roche Farma, S.A.. Budget: 59.904\u20ac. 2020- . PI: Nadal Alforja, Ernesto Samuel.<\/li>\n<\/ul>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\">More Information<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-3\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-3\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>The group has discovered how and why the cells die in conditions with a lack of nutrients<\/p>\n<p><em>Proyectos financiados por el Instituto de Salud Carlos III (ISCIII) y cofinanciados por el Fondo Europeo de Desarrollo Regional (FEDER):<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Se\u00f1alizaci\u00f3n c\u00e9lula-c\u00e9lula y muerte celular en respuesta a la falta de nutrientes y a la inhibici\u00f3n del metabolismo tumoral<\/strong><\/p>\n<p>PI13\/00139. 01\/2014-09\/2017. 127.500 \u20ac. IP: Cristina Mu\u00f1oz Pinedo.<\/p>\nLas c\u00e9lulas tumorales son dependientes de la glucosa como fuente de energ\u00eda y tambi\u00e9n como fuente del carbono necesario para la producci\u00f3n de macromol\u00e9culas. Por este motivo, y tambi\u00e9n debido a varias mutaciones oncog\u00e9nicas, son m\u00e1s sensibles a la falta de glucosa que las c\u00e9lulas no transformadas. En este proyecto buscamos caracterizar respuestas intr\u00ednsecas a la falta de glucosa y al tratamiento con 2-deoxiglucosa; y mol\u00e9culas secretadas que medien la comunicaci\u00f3n c\u00e9lula-c\u00e9lula en respuesta a estos est\u00edmulos.<br \/>\n<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2019\/12\/calldeath.png\" alt=\"\" width=\"249\" height=\"150\" \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/11\/Cristina-Munoz-Pinedo22-150x150.jpg\" alt=\"Cristina-Mu\u00f1oz-Pinedo22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Cristina-Mu\u00f1oz-Pinedo22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMu\u00f1oz Pinedo, Cristina\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:cmunoz@idibell.cat\" title=\"cmunoz@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tcmunoz@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2019\/09\/nadal-alforja-ernesto-samuel-150x150.jpg\" alt=\"Nadal Alforja, Ernesto Samuel\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"nadal-alforja-ernesto-samuel\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tNadal Alforja, Ernest\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:enadal@idibell.cat\" title=\"enadal@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tenadal@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tPrincipal investigators\n\t<\/h2>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/11\/Cristina-Munoz-Pinedo22-150x150.jpg\" alt=\"Cristina-Mu\u00f1oz-Pinedo22\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Cristina-Mu\u00f1oz-Pinedo22\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tMu\u00f1oz Pinedo, Cristina\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:cmunoz@idibell.cat\" title=\"cmunoz@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tcmunoz@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2019\/09\/nadal-alforja-ernesto-samuel-150x150.jpg\" alt=\"Nadal Alforja, Ernesto Samuel\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"nadal-alforja-ernesto-samuel\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tNadal Alforja, Ernest\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:enadal@idibell.cat\" title=\"enadal@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\tenadal@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2023\/02\/Ivan-Macia-Vidueira-150x150.jpg\" alt=\"Ivan-Mac\u00eda-Vidueira\" itemprop=\"image\" height=\"150\" width=\"150\" title=\"Ivan-Mac\u00eda-Vidueira\" onerror=\"this.style.display='none'\"  \/>\n<h4>\n\t\tIvan Mac\u00eda Vidueira\n\t<\/h4>\n<h4>\n\t\t<a href=\"mailto:imacia@idibell.cat\" title=\"imacia@idibell.cat\" target=\"_blank\" rel=\"noopener\">\n\t\timacia@idibell.cat\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\tRELATED LINKS\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/www.facebook.com\/apoptosislab\/\" target=\"_blank\" rel=\"noopener\">\n\t\tFacebook: &#8220;Cell Death&#8221;\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.apoptosis.es\/\" title=\"ApoList archive\" target=\"_blank\" rel=\"noopener\">\n\t\tApoList archive\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.cancer-metabolism.org\/\" title=\"Lab MetaboList archive: Recopilaci\u00f3n\" target=\"_blank\" rel=\"noopener\">\n\t\tLab MetaboList archive: Recopilaci\u00f3n\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.metacan.eu\/\" title=\"Marie Curie network META-CAN\" target=\"_blank\" rel=\"noopener\">\n\t\tMarie Curie network META-CAN\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/meta_canproject\" title=\"@meta_canproject\" target=\"_blank\" rel=\"noopener\">\n\t\t@meta_canproject\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.deathbase.org\/\" title=\"DeathBase\" target=\"_blank\" rel=\"noopener\">\n\t\tDeathBase\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"http:\/\/www.apored.es\/\" title=\"Apored\" target=\"_blank\" rel=\"noopener\">\n\t\tApored\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/apoptosislab\" title=\"@apoptosislab\" target=\"_blank\" rel=\"noopener\">\n\t\t@apoptosislab\n\t\t<\/a>\n\t<\/h4>\n<h4>\n\t\t<a href=\"https:\/\/twitter.com\/NadalErnest\" title=\"@NadalErnest\" target=\"_blank\" rel=\"noopener\">\n\t\t@NadalErnest\n\t\t<\/a>\n\t<\/h4>\n<h2>\n\t\tTeam\n\t<\/h2>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-0\" data-index=\"0\" aria-selected=\"true\" aria-controls=\"fl-tabs--panel-0\" aria-expanded=\"true\" role=\"tab\" tabindex=\"0\">\t\t\t\tGroup leaders\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-1\" data-index=\"1\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-1\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPrincipal investigators\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-2\" data-index=\"2\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-2\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tClinical researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-3\" data-index=\"3\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-3\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPostdoctoral researchers \t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-4\" data-index=\"4\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-4\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tPredoctoral researchers\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-5\" data-index=\"5\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-5\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tScientific support\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-tabs--label-6\" data-index=\"6\" aria-selected=\"false\" aria-controls=\"fl-tabs--panel-6\" aria-expanded=\"false\" role=\"tab\" tabindex=\"0\">\t\t\t\tManagement support\t\t\t\t<\/a>\n\t\t\t\t\t\tGroup leaders\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Mu\u00f1oz Pinedo, Cristina<\/li>\n<li>Nadal Alforja, Ernest<\/li>\n<\/ul>\n\t\t\t\t\t\tPrincipal investigators\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Ivan Mac\u00eda Vidueira<\/li>\n<\/ul>\n\t\t\t\t\t\tClinical researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Palmero Sanchez, Ramon<\/li>\n<li>Jov\u00e9 Casulleras, Maria<\/li>\n<li>Vilari\u00f1o Quintela, Noelia<\/li>\n<\/ul>\n\t\t\t\t\t\tPostdoctoral researchers \n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Gausachs Romero, Mireia<\/li>\n<li>Cordero Romera, David<\/li>\n<li>Hijazo Pechero, Sara<\/li>\n<\/ul>\n\t\t\t\t\t\tPredoctoral researchers\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Alay Badosa, Ania<\/li>\n<li>Collado Rodr\u00edguez, Lidia<\/li>\n<li>Cruz Rodr\u00edguez, Mabel<\/li>\n<li>Jimenez Hernandez Felipe<\/li>\n<li>Mar\u00edn Montes, Ra\u00fal<\/li>\n<li>Plans i Marin, S\u00edlvia<\/li>\n<\/ul>\n\t\t\t\t\t\tScientific support\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Barroso Barquilla, David<\/li>\n<li>Ajenjo Bauza, Maria<\/li>\n<li>Delgado De La Iglesia, Eduardo<\/li>\n<\/ul>\n\t\t\t\t\t\tManagement support\n\t\t\t\t\t\t\t\t\t\t\t<ul>\n<li>Moreno Caceres, Joaquim<\/li>\n<li>Ruiz Mitjana, Anna<\/li>\n<\/ul>\n<h2>\n\t\tRelated news\n\t<\/h2>\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/23646\" content=\"The first Innovation Conference on the Diagnosis and Treatment of Lung Cancer Patients at Bellvitge Campus takes place\" \/><meta itemprop=\"datePublished\" content=\"2024-02-16\" \/><meta itemprop=\"dateModified\" content=\"2024-02-16\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta 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itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2024\/01\/231219-Conxi-Ernest-002.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/01\/scientists-find-how-to-define-targeted-therapies-in-lung-cancer-usingthanks-to-a-genetic-sequencing-platform\/\" title=\"Scientists find how to define targeted therapies in lung cancer thanks to a genetic sequencing platform\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2024\/01\/scientists-find-how-to-define-targeted-therapies-in-lung-cancer-usingthanks-to-a-genetic-sequencing-platform\/\" title=\"Scientists find how to define targeted therapies in lung cancer thanks to a genetic sequencing platform\">Scientists find how to define targeted therapies in lung cancer thanks to a genetic sequencing platform<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t04\/01\/2024\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/22924\" content=\"First clinical trial of a treatment that attacks lung cancer and brain metastasis at the same time\" \/><meta itemprop=\"datePublished\" content=\"2023-08-22\" \/><meta itemprop=\"dateModified\" content=\"2023-10-06\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2023\/08\/DSC0853-scaled.jpg\" \/><meta itemprop=\"width\" content=\"2560\" \/><meta itemprop=\"height\" content=\"1704\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/08\/first-clinical-trial-of-a-treatment-that-attacks-lung-cancer-and-brain-metastasis-at-the-same-time\/\" title=\"First clinical trial of a treatment that attacks lung cancer and brain metastasis at the same time\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/08\/first-clinical-trial-of-a-treatment-that-attacks-lung-cancer-and-brain-metastasis-at-the-same-time\/\" title=\"First clinical trial of a treatment that attacks lung cancer and brain metastasis at the same time\">First clinical trial of a treatment that attacks lung cancer and brain metastasis at the same time<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t22\/08\/2023\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/22790\" content=\"A new treatment for lung cancer increases survival and could benefit more than 6,000 patients a year\" \/><meta itemprop=\"datePublished\" content=\"2023-06-29\" \/><meta itemprop=\"dateModified\" content=\"2023-06-29\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2023\/06\/NP13-E-Nadal_NADIMII-Imatge-noti.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/06\/a-new-treatment-for-lung-cancer-increases-survival-and-could-benefit-more-than-6000-patients-a-year\/\" title=\"A new treatment for lung cancer increases survival and could benefit more than 6,000 patients a year\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2023\/06\/a-new-treatment-for-lung-cancer-increases-survival-and-could-benefit-more-than-6000-patients-a-year\/\" title=\"A new treatment for lung cancer increases survival and could benefit more than 6,000 patients a year\">A new treatment for lung cancer increases survival and could benefit more than 6,000 patients a year<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t29\/06\/2023\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/21714\" content=\"A receptor until now considered a death promoter in tumor cells could induce the growth of lung cancer\" \/><meta itemprop=\"datePublished\" content=\"2022-12-28\" \/><meta itemprop=\"dateModified\" content=\"2022-12-23\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/12\/NP31-C-Munoz_CDDIS-Imatge-noti.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/12\/a-receptor-until-now-considered-a-death-promoter-in-tumor-cells-could-induce-the-growth-of-lung-cancer\/\" title=\"A receptor until now considered a death promoter in tumor cells could induce the growth of lung cancer\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/12\/a-receptor-until-now-considered-a-death-promoter-in-tumor-cells-could-induce-the-growth-of-lung-cancer\/\" title=\"A receptor until now considered a death promoter in tumor cells could induce the growth of lung cancer\">A receptor until now considered a death promoter in tumor cells could induce the growth of lung cancer<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t28\/12\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/20768\" content=\"Ernest Nadal presents at ASCO the benefits of treating patients with lung cancer and brain metastases with chemo-immunotherapy\" \/><meta itemprop=\"datePublished\" content=\"2022-06-14\" \/><meta itemprop=\"dateModified\" content=\"2022-06-14\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/06\/NO63-E-Nadal_ASCO-Imatge-scaled.jpg\" \/><meta itemprop=\"width\" content=\"2560\" \/><meta itemprop=\"height\" content=\"1441\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/06\/ernest-nadal-presents-at-asco-the-benefits-of-treating-patients-with-lung-cancer-and-brain-metastases-with-chemo-immunotherapy\/\" title=\"Ernest Nadal presents at ASCO the benefits of treating patients with lung cancer and brain metastases with chemo-immunotherapy\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/06\/ernest-nadal-presents-at-asco-the-benefits-of-treating-patients-with-lung-cancer-and-brain-metastases-with-chemo-immunotherapy\/\" title=\"Ernest Nadal presents at ASCO the benefits of treating patients with lung cancer and brain metastases with chemo-immunotherapy\">Ernest Nadal presents at ASCO the benefits of treating patients with lung cancer and brain metastases with chemo-immunotherapy<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t14\/06\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/19669\" content=\"A worm model allows the study of adverse effects of the most common chemotherapy against solid tumors and improves its effectiveness\" \/><meta itemprop=\"datePublished\" content=\"2022-02-16\" \/><meta itemprop=\"dateModified\" content=\"2022-02-16\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/02\/NO07-J-Ceron_DMM-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/02\/a-worm-model-allows-the-study-of-adverse-effects-of-the-most-common-chemotherapy-against-solid-tumors-and-improves-its-effectiveness\/\" title=\"A worm model allows the study of adverse effects of the most common chemotherapy against solid tumors and improves its effectiveness\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2022\/02\/a-worm-model-allows-the-study-of-adverse-effects-of-the-most-common-chemotherapy-against-solid-tumors-and-improves-its-effectiveness\/\" title=\"A worm model allows the study of adverse effects of the most common chemotherapy against solid tumors and improves its effectiveness\">A worm model allows the study of adverse effects of the most common chemotherapy against solid tumors and improves its effectiveness<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t16\/02\/2022\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/19217\" content=\"Sara Hijazo was awarded for the best &#8216;oral communication&#8217; at the XIV Congress of Lung Cancer\" \/><meta itemprop=\"datePublished\" content=\"2021-12-01\" \/><meta itemprop=\"dateModified\" content=\"2021-12-01\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/12\/sara-hijazo-2021.jpg_2065046318.jpg\" \/><meta itemprop=\"width\" content=\"450\" \/><meta itemprop=\"height\" content=\"242\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/12\/sara-hijazo-was-awarded-for-the-best-oral-communication-at-the-xiv-congress-of-lung-cancer\/\" title=\"Sara Hijazo was awarded for the best &#8216;oral communication&#8217; at the XIV Congress of Lung Cancer\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/12\/sara-hijazo-was-awarded-for-the-best-oral-communication-at-the-xiv-congress-of-lung-cancer\/\" title=\"Sara Hijazo was awarded for the best &#8216;oral communication&#8217; at the XIV Congress of Lung Cancer\">Sara Hijazo was awarded for the best &#8216;oral communication&#8217; at the XIV Congress of Lung Cancer<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t01\/12\/2021\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/19188\" content=\"IDIBELL offers 10 projects for incoming INPhINIT fellowships\" \/><meta itemprop=\"datePublished\" content=\"2021-11-18\" \/><meta itemprop=\"dateModified\" content=\"2021-11-25\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/11\/FFBWFunXoAQfIw4-1.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/11\/idibell-offers-10-projects-for-incoming-inphinit-fellowships\/\" title=\"IDIBELL offers 10 projects for incoming INPhINIT fellowships\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/11\/idibell-offers-10-projects-for-incoming-inphinit-fellowships\/\" title=\"IDIBELL offers 10 projects for incoming INPhINIT fellowships\">IDIBELL offers 10 projects for incoming INPhINIT fellowships<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t18\/11\/2021\t\t\t\t\t\t\t\n\t<meta itemscope itemprop=\"mainEntityOfPage\" itemtype=\"https:\/\/schema.org\/WebPage\" itemid=\"http:\/\/18662\" content=\"Identified two drugs with antitumor activity in preclinical models of malignant pleural cancer\" \/><meta itemprop=\"datePublished\" content=\"2021-10-20\" \/><meta itemprop=\"dateModified\" content=\"2021-10-19\" \/><meta itemprop=\"name\" content=\"IDIBELL\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2022\/05\/Marca-B-e1651478109730.png\"\/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\" \/><meta itemprop=\"name\" content=\"comunicacio\" \/><meta itemprop=\"url\" content=\"https:\/\/idibell.cat\/en\/wp-content\/uploads\/sites\/2\/2021\/10\/NP38-E-Nadal_BJM-Imatge.jpg\" \/><meta itemprop=\"width\" content=\"1366\" \/><meta itemprop=\"height\" content=\"768\" \/><meta itemprop=\"interactionType\" content=\"https:\/\/schema.org\/CommentAction\" \/><meta itemprop=\"userInteractionCount\" content=\"0\" \/>\t\n\t\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/10\/identified-two-drugs-with-antitumor-activity-in-preclinical-models-of-malignant-pleural-cancer\/\" title=\"Identified two drugs with antitumor activity in preclinical models of malignant pleural cancer\"><\/a>\n\t\t\t<a href=\"https:\/\/idibell.cat\/en\/2021\/10\/identified-two-drugs-with-antitumor-activity-in-preclinical-models-of-malignant-pleural-cancer\/\" title=\"Identified two drugs with antitumor activity in preclinical models of malignant pleural cancer\">Identified two drugs with antitumor activity in preclinical models of malignant pleural cancer<\/a>\n\t\t\tBy <a href=\"https:\/\/idibell.cat\/en\/author\/comunicacio\/\">comunicacio<\/a>\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t  |  \n\t\t\t\t\t\t\t\t\t20\/10\/2021\t\t\t\t\t\t\t\n\t\t<!-- .pp-content-posts -->\n\n","protected":false},"excerpt":{"rendered":"<p>Preclinical and experimental research in thoracic tumors (PReTT) Summary The PReTT group focuses on the study of novel therapeutic strategies in thoracic tumours combining basic molecular and patient-oriented translational research, bioinformatics, and also design and development of investigator-initiated clinical trials. In terms of basic research, we study the mechanisms through which tumour cells die in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":448,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1732","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2024-11-12 03:44:58","action":"change-status","newStatus":"draft","terms":[],"taxonomy":""},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1732"}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/comments?post=1732"}],"version-history":[{"count":8,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1732\/revisions"}],"predecessor-version":[{"id":24575,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/1732\/revisions\/24575"}],"up":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/pages\/448"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=1732"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}