{"id":25434,"date":"2025-02-27T09:55:04","date_gmt":"2025-02-27T08:55:04","guid":{"rendered":"https:\/\/idibell.cat\/en\/?post_type=agenda&#038;p=25434"},"modified":"2025-02-27T15:24:15","modified_gmt":"2025-02-27T14:24:15","slug":"idibellseminars-developing-the-next-generation-of-ge-mouse-models-for-investigation-of-thoracic-cancers","status":"publish","type":"agenda","link":"https:\/\/idibell.cat\/en\/agenda\/idibellseminars-developing-the-next-generation-of-ge-mouse-models-for-investigation-of-thoracic-cancers\/","title":{"rendered":"#IDIBELLseminars: Developing the next generation of GE mouse models for investigation of thoracic cancers"},"content":{"rendered":"<p>Genetically engineered mouse models are increasingly used as avatars for the diseases they model, yielding mechanistic insight that is often inaccesible from analysis of patient-derived samples, as well as providing platforms for pre-clinical evaluation of new therapeutic strategies.\u00a0 GEMMs are however a work in progress and continuous refinement is needed to better recapitulate aspects of human cancers.\u00a0 I will discuss our attempts to improve mouse models of lung c\u00e1ncer and mesothelioma, along with new genetic tolos currently in development to address additional gaps in the ability to fathfully recapitulate processes at work in cancer progression<\/p>\n<p>&nbsp;<\/p>\n<p><i>Hosted by Cristina Mu\u00f1oz-Pinedo &#8211; Preclinical and experimental research in thoracic tumors (PReTT) group<\/i><\/p>\n","protected":false},"featured_media":25435,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"tags":[78],"class_list":["post-25434","agenda","type-agenda","status-publish","has-post-thumbnail","hentry","tag-cancer"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/agenda\/25434","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/agenda"}],"about":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/types\/agenda"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media\/25435"}],"wp:attachment":[{"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/media?parent=25434"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idibell.cat\/en\/wp-json\/wp\/v2\/tags?post=25434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}