The rise of large life on Earth in the form of animals was a fairly late and unique event in a 4.6 billion-year-long history, that we still do not fully understand. We have so far linked this event to a presumed rise in atmospheric oxygen (O2). However, a link between any rise in atmospheric O2 and the diversification of animals is not supported with clues from the geological record. Indeed, observations from within tissues (and tumors) even suggest that cell stemness is challenged by \u2018oxic\u2019 conditions. This makes it valuable to explore if instead the managment of hypoxia and hypoxia-responses are vital for tissues to form and tissue renewal to occur. I will present some such explorations to you, and look forward to hear your thoughts on these.<\/p>\n
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