{"id":16457,"date":"2021-04-25T22:03:14","date_gmt":"2021-04-25T20:03:14","guid":{"rendered":"https:\/\/idibell.cat\/en\/?post_type=agenda&p=16457"},"modified":"2021-04-25T22:04:35","modified_gmt":"2021-04-25T20:04:35","slug":"idibellseminars-surgical-treatment-of-peritoneal-metastases-of-gastrointestinal-cancer-origin-successes-challenges-and-oppportunities","status":"publish","type":"agenda","link":"https:\/\/idibell.cat\/en\/agenda\/idibellseminars-surgical-treatment-of-peritoneal-metastases-of-gastrointestinal-cancer-origin-successes-challenges-and-oppportunities\/","title":{"rendered":"#IDIBELLseminars: Surgical treatment of peritoneal metastases of gastrointestinal cancer origin: Successes, challenges and oppportunities"},"content":{"rendered":"

Lana Bijelic<\/strong>
\nPeritoneal Surface Malignaces and Complex Oncologic Surgery Unit, Hospital Sant Joan Desp\u00ed Mois\u00e8s Broggi<\/p>\n

Peritoneal metastases are a common but difficult to treat manifestation of gastrointestinal and gynecologic cancers. Surgical resection, in the form of cytoreductive surgery coupled with heated intraperitoneal chemotherapy, has developed over the last 20 years as a treatment option for selected patients with peritoneal metastases based on a significant positive impact on survival. The development of this new therapeutic approach has enabled new insights into the physiology of the peritoneal space, the pathophysiology of peritoneal metastases and the clinical and pathological variables correlated with improved outcomes. Many further avenues of research remain open and are emerging on the horizon including the role of the immune system in peritoneal metastases, molecular profiling and improved understanding of peritoneal metastases subtypes, identification of new markers of response to local-regional chemotherapy and optimization of new techniques for delivery of intraperitoneal chemotherapy such as pressurized aerosolization (PIPAC). This presentation will review the current status of surgical treatment of peritoneal metastases and discuss clinically relevant challenges that remain unaddressed.<\/p>\n

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