Infections of the Respiratory Tract and in Immunocompromised Patients

Summary

This group focusses its research activity on two main areas: on the one hand, respiratory infections, mainly community-acquired pneumonia and tuberculosis. On the other hand, it deals with immunocompromised-host infections, including cancer patients, haematopoietic stem-cell (bone marrow) and solid-organ transplant patients, and patients with HIV-AIDS infection. Its lines of research focus on various epidemiological, clinical, diagnostic, therapeutic and preventive aspects of these infections.

1293

Publications

Strategic lines

Selected Publications

- Abelenda Alonso G, Rombauts A, Gudiol C, Oriol I, Simonetti A, Coloma A, Rodríguez Molinero A, Izquierdo E, Díaz Brito V, Sanmartí M, Padullés A, Grau I, Ras M, Bergas A, Guillem L, Blanco Arévalo A, Alvarez Pouso C, Pallarés N, Videla S, Tebé C, Carratalà J. Immunomodulatory therapy, risk factors and outcomes of hospital-acquired bloodstream infection in patients with severe COVID-19 pneumonia: a Spanish case-control matched multicentre study (BACTCOVID). Clin. Microbiol. Infect. 2021;27(11):1685-1692. doi:10.1016/j.cmi.2021.06.041. IF:8,07.

- Rosas IO, Diaz G, Gottlieb RL, Lobo SM, Robinson P, Hunter BD, Cavalcante AW, Overcash JS, Hanania NA, Skarbnik A, Garcia Diaz J, Gordeev I, Carratala J, Gordon O, Graham E, Lewin Koh N, Tsai L, Tuckwell K, Cao HY, Brainard D, Olsson JK. Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial. Intensive Care Med. 2021;47(11):1258-1270. doi:10.1007/s00134-021-06507-x. IF:17,44.

- Aydillo T, Rombauts A, Stadlbauer D, Aslam S, Abelenda Alonso G, Escalera A, Amanat F, Jiang K, Krammer F, Carratala J, Garcia Sastre A. Immunological imprinting of the antibody response in COVID-19 patients. Nat. Commun. 2021;12(1):3781-3781. doi:10.1038/s41467-021-23977-1. IF:14,92.

- Gutierrez B, del Toro MD, Borobia AM, Carcas A, Jarrin I, Yllescas M, Ryan P, Pachon J, Carratala J, Berenguer J, Arribas JR, Rodriguez Bano J, REIPI 19 GRP, COVID HULP GRP. Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study. Lancet Infect Dis. 2021;21(6):783-792. doi:10.1016/S1473-3099(21)00019-0. IF:25,07.

Selected Projects

- 20FIS052. Identificación del perfil transcripómico dinámico en pacientes con COVID-19 y síndrome de distrés respiratorio agudo (TRANSCOVID). (COV20/00121). 2020-2021. IP:CARRATALA FERNANDEZ,JORDI.

- 19MAR001. Impact of comprehensive molecular testing to reduce antibiotic use in community-acquired pneumonia: a randomized controlled trial. (201808-10). FUNDACIÓ LA MARATÓ DE TV3. 2019-2022. IP:CARRATALA FERNANDEZ,JORDI.

- 19FIS034. Estudio de las reversiones de una prueba de liberación de interferón-? (QuantiFERON-TB Gold Plus) para la optimización del estudio de contactos de tuberculosis. (PI18/00423). ISCIII. 2019-2021. IP:SANTIN CEREZALES,MIGUEL.

- 18FIS020. Eficacia de la infusión extendida de los antibióticos ß-lactámicos en el tratamiento de la neutropenia febril en los pacientes hematológicos. (PI17/01372). ISCIII. 2018-2022. IP:GUDIOL GONZALEZ,CARLOTA.

- 17CEE003. ANTI-SUPERBUG Precommercial procurement. (688878). AQUAS (AG. DE QUALITAT I AVALUACIO S. C); BEDIN SARA; COMISSIÓ EUROPEA; FUND.DOCENCIA I RECERCA MUTUA TERRA; FUNDACIO IDIBELL; HELIOS KLINIKUM WUPPERTAL GMBH; INSTITUT CATALA D'ONCOLOGIA; PROVINCIA AUTONOMA DI TRENTO; RISE ACREO AB; RISE RESEARCH INSTITUTES OF SWEDEN AB; SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST; UNIVERSITAETSKLINIKUM AACHEN. 2017-2022. IP:LIMON CACERES,ENRIQUE.