Neurodevelopmental disorders

- Functional neurogenomics
- Biomimetic strategies for driving neural development and regeneration
- Human modeling of neurological disorders

Gleixner, A. M., Verdone, B. M., Otte, C. G., Anderson, E. N., Ramesh, N., Shapiro, O. R., Gale, J. R., Mauna, J. C., Mann, J. R., Copley, K. E., Daley, E. L., Ortega, J. A., Cicardi, M. E., Kiskinis, E., Kofler, J., Pandey, U. B., Trotti, D., & Donnelly, C. J. NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility. Nature Communications . doi: 10.1038/s41467-022-31098-6

Alvarez A., Edelbrock A.N., Sasselli I.R., Ortega J.A., Syrgiannis Z., Mireau P.A., Cheng F., Qiu R., Chin S.M., Kiskinis E., Stupp S.I. Supramolecular Motions Enhance Biological Signaling by Fibril Scaffolds: Spinal Cord Injury Recovery. 2021. Science, 374, 848-856.

Borsari B, Villegas Miron P, Perez Lluch S, Turpin I, Laayouni H, Segarra Casas A, Bertranpetit J, Guigo R, Acosta S. Enhancers with tissue-specific activity are enriched in intronic regions. Genome Res. 2021;31(8):1325-1336. doi:10.1101/gr.270371.120.

Castells AA, Balada R, Tristan Noguero A, O'Callaghan M, Cortes Saladelafont E, Pascual Alonso A, Garcia Cazorla A, Armstrong J, Alcántara S. Unraveling Molecular Pathways Altered in MeCP2-Related Syndromes, in the Search for New Potential Avenues for Therapy. Biomedicines. 2021;9(2):doi:10.3390/biomedicines9020148.

Farré X., Molina R., Barteri F., Timmers P.R.H.J, Joshi P.K., Oliva B., Acosta, S., Esteve-Altava B., Navarro A.*, Muntané G*. Comparative analysis of mammal genomes unveils key genomic variability for human lifespan. 2021 Oct 27;38(11):4948-4961.doi: 10.1093/molbev/msab219.

PUB22026. INVESTIGO 2022 . SERVICIO PUBLICO DE EMPLEO ESTATAL SEPE. Budget: 66217,68. - . PI: Ortega Cano, Juan Alberto.
21VAR006. NEUROIMPULSE . Budget: 5400. 2022. PI: Ortega Cano, Juan Alberto.