Radiobiology & Cancer

Study on:
1. How high doses of radiotherapy (SBRT, IORT and HDR) could trigger immune stimulation through modulation of cytokines and immune cells in plasma.
2. Predictive radiation sensitivity tests.
3. New therapeutic strategies in brachytherapy.
4. New therapeutic strategies in external radiotherapy.
5. Evaluation of quality of life in the treatment of prostate cancer.
6. Application of intracranial stereotactic radiotherapy (SRT) and
7. Stereotactic body radiotherapy (SBRT) techniques.

Systematic review of educational interventions to improve contouring in radiotherapy

Cacicedo, Jon; Navarro-Martin, Arturo; Gonzalez-Larragan, Susana; De Bari, Berardino; Salem, Ahmed; Dahele, Max

RADIOTHERAPY AND ONCOLOGY. 2020, doi: 10.1016/j.radonc.2019.11.004

Minimizing acquisition-related radiomics variability by image resampling and batch effect correction to allow for large-scale data analysis

Ligero, Marta; Jordi-Ollero, Olivia; Bernatowicz, Kinga; Garcia-Ruiz, Alonso; Delgado-Munoz, Eric; Leiva, David; Mast, Richard; Suarez, Cristina; Sala-Llonch, Roser; Calvo, Nahum; Escobar, Manuel; Navarro-Martin, Arturo; Villacampa, Guillermo; Dienstmann, Rodrigo; Perez-Lopez, Raquel

EUROPEAN RADIOLOGY. 2020, doi: 10.1007/s00330-020-07174-0

Short-Course Radiotherapy in Locally Advanced Rectal Cancer

Cambray, Maria; Gonzalez-Viguera, Javier; Angel Berenguer, Miguel; Macia, Miquel; Losa, Ferran; Soler, Gemma; Frago, Ricard; Castellvi, J.; Guino, E.

Clinical And Translational Gastroenterology. 2020, doi: 10.14309/ctg.0000000000000162

Can we avoid axillary lymph node dissection in N2 breast cancer patients with chemo-sensitive tumours such as HER2 and TNBC?

Garcia-Tejedor, Amparo; Fernandez-Gonzalez, Sergi; Ortega, Raul; Gil-Gil, Miguel; Perez-Montero, Hector; Fernandez-Montoli, Eulalia; Stradella, Agostina; Recalde, Sabela; Soler, Teresa; Petit, Anna; Bajen, Maria Teresa; Benitez, Ana; Guma, Anna; Campos, Miriam; Pla, Maria J.; Martinez, Evelyn; Laplana, Maria; Pernas, Sonia; Perez-Sildekova, Diana; Catala, Isabel; Ponce, Jordi; Falo, Catalina

BREAST CANCER RESEARCH AND TREATMENT. 2020, doi: 10.1007/s10549-020-05970-2

Chromosomal aberration dynamics through the cell cycle

Pujol-Canadell, Monica; Puig, Roser; Armengol, Gemma; Barrios, Leonardo; Barquinero, Joan-Francesc

DNA REPAIR. 2020, doi: 10.1016/j.dnarep.2020.102838

Estudio de fase 3 aleatorizado, doble ciego y controlado con placebo de JNJ-56021927 en sujetos con cáncer de próstata localizado o localmente avanzado y de alto riesgo que están recibiendo tratamiento con radioterapia primaria

Boladeras Inglada, ana Maria (Principal investigator (IP))

Funder:

• Janssen Cilag International N.V.

2016-2026

Prevalencia y caracterización del dolor irruptivo en pacientes oncológicos en tratamiento con RT 3D pélvica con proctalgia

Marin Borras, Susanna (Principal investigator (PI))

Funder:

• KIOWA KIRIN FARMACÉUTICA

2017-2026

Optimizing irradiation through molecular assessment of lymphnode (OPTIMAL)

Eraso Urién, Maria Aranzazu (Principal investigator (PI))

Funder:

• GICOR (Grupo de Investigación Clinica en Oncologia Radioterápica)

2015-2022

We currently have three industry-funded projects under way:

Immune modulation through brachytherapy in blood and tumour microenvironment.
Detection of systemic immune response to peripheral blood provided by high doses of radiation given to the lung in stereotactic conditions.
INTRABEAM: precision hypofractionated radiotherapy with immune-system response.
Over the past five years, we have obtained two competitive projects, Healthcare Research and Development Strategy grants:
Long-term effectiveness: 10-year follow-up of the “Spanish Multicentre Study of Localised Prostate Cancer” cohort (PI13 / 00412).
Efficacy of new treatments for low-risk localised prostate cancer: a randomised clinical trial (PI13 / 00412).