Metabolism and Cancer

Summary

The Metabolism and Cancer group includes Doctors George Thomas, Sara Kozma, Albert Tauler and Antonio Gentilella. The program focuses on the kinase signalling of the mammalian target of rapamycin complex 1 (mTORC1) and its main metabolic cascade responses, including ribosome biogenesis, control of translation, metabolic reprogramming, autophagy, lysosomal transport and cell proliferation. The group’s aim is to unveil metabolic vulnerabilities in cancer to promote new clinical treatments, using colorectal cancer (CRC) and other c-MYC driven tumor models and by interacting with oncologists and pharmaceutical companies.

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Publications

metabolism-and-cancer3
Thomas, George

Thomas, George

Principal investigators

Thomas, George

Thomas, George

Antonio-Gentilella-q

Gentilella, Antonio

tauler-girona-albert

Tauler Girona, Albert

Team

Group leaders
  • Thomas, George
Principal investigators
Postdoctoral researchers (R2)
Predoctoral researchers (R1)
Scientific support
Collaborators
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