Apoptosis and cancer

Summary

The Apoptosis and Cancer group studies the mechanism of action of fluorizoline, a fluorate thiazoline compound, which is part of a new class of proapoptotic compounds and candidates to become anticancer agents, which have been discovered and reported by the group. The group also works towards evaluating the role of tumour stem cells in the therapeutic resistance of human glioblastoma and ovarian cancer at the cell and molecular mechanism level.

232 Publications

Strategic lines

Selected Publications

Navarro Sabate,A;Font,R;Martínez Soler,F;Solà,J;Tortosa,A;Ribes,J;Benito Aracil,L et al, The Impact of the COVID-19 Pandemic on Adherence to Endocrine Therapy for Breast Cancer in Catalonia (Spain), Cancers, 2024;16(2):doi:10.3390/cancers16020426
Presague Peciña,M;Giménez Bonafé,P, Comparative study of trans* healthcare models in Catalonia, Heliyon, 2024;10(18):doi:10.1016/j.heliyon.2024.e36174
Cabrero,EL;Robledo,RT;Cuñado,AC;Sardelli,DG;Huerta,CM;Perez,LL;Estevez,PE et al, The Midline Catheter Within the Context of Home Intravenous Antibiotic Treatment, J. Infus.Nurs., 2024;47(6):369-376, doi:10.1097/NAN.0000000000000559
Espinosa Sotelo,R;Fuste,NP;Penuelas Haro,I;Alay,A;Pons,G;Almodovar,X;Albaladejo,J et al, Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma, Redox Biol., 2023;65102818-102818, doi:10.1016/j.redox.2023.102818
Pedrosa,L;Bedia,C;Diao,DL;Mosteiro,A;Ferres,A;Stanzani,E;Martinez Soler,F et al, Preclinical Studies with Glioblastoma Brain Organoid Co-Cultures Show Efficient 5-ALA Photodynamic Therapy, Cells, 2023;12(8):doi:10.3390/cells12081125

Selected Projects

- FIS22046. Desarrollo de estrategias terapéuticas para disminuir la resistencia a tratamientos convencionales en cáncer de pulmón. Instituto de Salud Carlos III (ISCIII). Budget: 141.570€. 2023-2025. PI: Soto Cerrato, Vanessa.

- PID2020-120537RB-I00. Mecanismos de control de la apoptosis por prohibitina en células tumorales. Ministerio de Ciencia e Innovación. IP: Joan Gil Santano. (Universitat de Barcelona). 01/10/2021-31/9/2024. 181.500 €.

- PIFIISC19/24. Desarrollo y evaluación de una intervención sobre Atención Centrada en la Persona y Alfabetización Digital en Salud en Cáncer de Mama. Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC). IP: Yolanda Alvarez Perez. (Servicio de Evaluación del Servicio Canario de la Salud). Participació: Pepita Giménez Bonafé. 01/01/2020-31/12/2022. Import concedit: 17.419.61€.

- Grup consolidat de l’AGAUR “Apoptosi i cáncer”. IP: Joan Gil Santano

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