Infections and Cancer

Summary

The Infections and Cancer group focusses on the fight between viruses and hosts, from an evolutionary perspective: the antiviral mechanisms which animals have developed and the antiviral strategies which have contributed to virus selection. It researches the connection between infection and cancer, as exemplified by the human papilloma virus (HPV).

925 Publications

Strategic lines

Human papilloma virus (HPV) and genital cancer.
HPV and cancer of the oesophagus, oral cavity, skin, vagina, vulva, penis and anus.
Hepatotropic viruses (hepatitis B and C virus – HBV, HCV) and cancer of the liver.
Trials on HPV vaccination and intervention studies on cancer prevention.
Infectious aetiology of malignant lymphomas.
WHO/ICO HPV and Cervical Cancer Information Centre.
Development of logistics instruments for coordination and diffusion of information regarding viruses and cancer.
Screening and prevention of genital cancer.
Evaluation of virus detection technologies.
Financial modelling and evaluation of cancer prevention measures.

Selected Publications

- Robles C, Bruni L, Acera A, Riera JC, Prats L, Poljak M, Mlakar J, Valencak AO, Eriksson T, Lehtinen M, Louvanto K, Hortlund M, Dillner J, Faber MT, Munk C, Kjaer SK, Petry KU, Denecke A, Xu L, Arbyn M, Cadman L, Cuzick J, Dalstein V, Clavel C, de Sanjose S, Bosch FX. Determinants of Human Papillomavirus Vaccine Uptake by Adult Women Attending Cervical Cancer Screening in 9 European Countries. Am. J. Prev. Med. 2021;60(4):478-487. doi:10.1016/j.amepre.2020.08.032. IF:5,04.

- Cocco P, Satta G, Meloni F, Pilia I, Ahmed F, Becker N, Casabonne D, de Sanjose S, Foretova L, Maynadie M, Nieters A, Staines A, 't Mannetje A, Zucca M, Ennas MG, Campagna M, De Matteis S, Benavente Y. Occupational exposure to organic dust and risk of lymphoma subtypes in the EPILYMPH case-control study. SCAND J WORK ENV HEA. 2021;47(1):42-51. doi:10.5271/sjweh.3925. IF:5,02.

- Morina D, Fernandez Fontelo A, Cabana A, Puig P, Monfil L, Brotons M, Diaz M. Quantifying the under-reporting of uncorrelated longitudal data: the genital warts example. BMC Med Res Methodol. 2021;21(1):6-6. doi:10.1186/s12874-020-01188-4. IF:4,62.

- Frias Gomez J, Tovar E, Vidal A, Murgui L, Ibáñez R, Peremiquel Trillas P, Paytubi S, Baixeras N, Zanca A, Ponce J, Pineda M, Brunet J, de Sanjosé S, Bosch FX, Matias Guiu X, Alemany L, Costas L, Screenwide T. Sensitivity of cervical cytology in endometrial cancer detection in a tertiary hospital in Spain. Cancer Med. 2021;10(19):6762-6766. doi:10.1002/cam4.4217. IF:4,45.

- Ferreiro Iglesias A, McKay JD, Brenner N, Virani S, Lesseur C, Gaborieau V, Ness AR, Hung RJ, Liu G, Diergaarde B, Olshan AF, Hayes N, Weissler MC, Schroeder L, Bender N, Pawlita M, Thomas S, Pring M, Dudding T, Kanterewicz B, Ferris R, Thomas S, Brhane Y, Díez Obrero V, Milojevic M, Smith Byrne K, Mariosa D, Johansson MJ, Herrero R, Boccia S, Cadoni G, Lacko M, Holcátová I, Ahrens W, Lagiou P, Lagiou A, Polesel J, Simonato L, Merletti F, Healy CM, Hansen BT, NYGÅRDM, Conway DI, Wright S, Macfarlane TV, Robinson M, Alemany L, Agudo A, Znaor A, Amos CI, Waterboer T, Brennan P. Germline determinants of humoral immune response to HPV-16 protect against oropharyngeal cancer. Nat Commun. 2021;12(1):5945-5945. doi:10.1038/s41467-021-26151-9. IF:14,92.

Selected Projects

CEE21039. PERCH: PartnERship to Contrast HPV. COMISSIÓ EUROPEA. Budget: 409468,03. 2022-2025. PI: Brotons Agulló, Maria.

MCI22005. WOMEC ADVANCED : NUEVAS APROXIMACIONES PARA EL DIAGNÓSTICO DE CÁNCER DE ENDOMETRIO. Ministerio de Ciencia e Innovación. Budget: 194288. 2022-2025. PI: Costas Caudet, Laura.

19CEE002. HEADSpAcE: Translational studies of HEAD and neck cancer in South America and Europe. COMISSIÓ EUROPEA. Budget: 249985. 2019-2023. PI: Alemany Vilches, Laia.

PNJ22019. Reduction of VIral InFectivity and Transmission in HPV positive women before and after vaccination with GARDASIL-9. The effect in oral and anal body fluids and after 1- or 2- vaccine doses (RIFT-HPV II). MERCK SHARP & DOHME ESPAÑA S.A.. Budget: 140478,25. 2021- . PI: Bosch José, Francesc Xavier.

FIS21057. Human papillomavirus protection index (HPV-PI). Instituto de Salud Carlos III (ISCIII). Budget: 47190. 2022-2024. PI: Bruni Coccoz, Laia.