Tumor and stromal chemoresistance

Summary

Our group addresses different aspects of chemoresistance using advanced animal models (orthoxenografts) and non-tumour cell models, such as cancer-associated fibroblasts, to study mechanisms of therapeutic resistance in solid and hematological tumors.

Orthoxenografts® are experimental mouse models in which a small piece of human tumour is implanted (implantation from one spices to another, xenograft) in the same organ of origin (orthotopically). Orthoxenografts® are characterised by reproducing the histological, genetic and molecular characteristics of the original primary tumour, representing an excellent scientific tool for predicting patient response to chemotherapy treatment, and providing treatment alternatives based on scientific evidence.

 

367

Publications

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Villanueva Garatachea, Alberto

Villanueva Garatachea, Alberto

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Garcia Mollevi, David

Principal investigators

Villanueva Garatachea, Alberto

Villanueva Garatachea, Alberto

garcia-mollevi-david

Garcia Mollevi, David

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Farre Vallve, María Lourdes

Team

Group leaders
  • Villanueva Garatachea, Alberto
  • Garcia Mollevi, David
Principal investigators
Clinical researchers
Predoctoral researchers
Scientific support
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