A team from the Cancer Research Centre (University of Salamanca-CSIC), led by Javier Vaquero, and other from IDIBELL, led by Isabel Fabregat, have developed a key study published in the journal Signal transduction and targeted therapy that proposes an innovative strategy to slow the growth of cholangiocarcinoma, a type of liver cancer with a poor prognosis. The work on intrahepatic cholangiocarcinoma identifies a new therapeutic target that allows tumour progression to be blocked in a specific way and with fewer side effects. The research results are a milestone in understanding the mechanisms that regulate tumor growth in cholangiocarcinoma and provide a solid foundation for the development of future more effective and safer therapies.