October 2020

Funding to study new drugs against autoimmune diseases

IDIBELL researcher Josep Maria Aran and his research group will receive 100,000 euros from the aid Product from the AGAUR agency of the Generalitat de Catalunya. They will study two molecules that act on the immune system as possible treatments for autoimmune diseases.

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The lack of interaction between two neuronal receptors is a determining factor in schizophrenia

The interaction of these two receptors leads to the inhibition of the dopaminergic pathway, which in this disorder is abnormally active. This discovery opens the door to the design of new drugs for the treatment of schizophrenia that acts on this interaction.

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Blood concentrations of polyphenols are not clearly related to the risk of thyroid cancer

Although polyphenols have shown anticarcinogenic activity in previous in vitro studies, the epidemiological study led by IDIBELL and the ICO has found no association between their concentration in blood and thyroid cancer.

Blood concentrations of polyphenols are not clearly related to the risk of thyroid cancer Read More »

Researchers identify connection patterns in the brain that indicate the risk of developing obsessive disorders in children

A group of researchers from IDIBELL, CIBERSAM and the Hospital de Bellvitge have identified changes in the connection between the frontal cortex and subcortical regions in girls and boys with mild symptoms of obsessive-compulsive disorder (OCD).

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Study supports use of the nutrition label Nutri-Score to encourage healthier food choices

Results could inform discussions on food packaging labels across Europe, say researchers. The study has the participation of Antonio Agudo and has been published in the journal The BMJ.

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Presented a program capable of automatically detecting neurodegeneration biomarkers through magnetic resonance imaging

This tool is able to identify single-person neurodegeneration before the symptom’s appearance, which could significate a more effective and personalized medicine.

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The Administration of chemo-immunotherapy before lung cancer surgery could improve its prognosis and significantly reduce tumor volume

A study has evaluated the efficacy and safety of the combination of 3 cycles of chemotherapy with immunotherapy before surgery, in 51 patients with locally advanced lung cancer, followed by one year of treatment with immunotherapy.

The Administration of chemo-immunotherapy before lung cancer surgery could improve its prognosis and significantly reduce tumor volume Read More »

A study of DNA sequencing biomarkers shows that the number and clonality of TCRs are associated with the prognosis of colorectal cancer

This study has used a new technique called ‘T-cell receptor (TCR) immuno-sequencing’, which allows us to obtain both the number of T lymphocytes that infiltrate the tumor and their clonality index.

A study of DNA sequencing biomarkers shows that the number and clonality of TCRs are associated with the prognosis of colorectal cancer Read More »

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